Overview of SARS-CoV-2 Mutation, Integration-Cistrome Factor Overlap and Target gene

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic.
Size: 30kb
Encoding: N, 3CLpro, E, M, Mpro, NSP12, NSP13, NSP14, NSP15, NSP2, NSP3, NSP4, NSP5, NSP6, NSP7, NSP8, ORF1a, ORF1ab, ORF1b, ORF3a, ORF6, ORF7a, ORF8, PLpro, RBD, RdRp, S, etc.
Human Disease: COVID-19, etc.
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SARS-CoV-2 Mutation Info
Only show 100 info Click here to see all SARS-CoV-2 Mutation Sites
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37153142 D405N
S
S
COVID-19
G
R
S
I
View
2 37153142 T95I
S
S
COVID-19
G
R
S
I
View
3 37243229 R346T
RBD
S
COVID-19
G
S
View
4 37529147 Q954H
S
S
COVID-19
G
R
S
L
View
5 34403732 Y453F
S
S
Cell line
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6 34433426 D614G
S
S
Cell line
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7 34445669 D614G
S
S
Cell line
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8 34467913 A222V
S
S
Cell line
R
S
L
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9 34467913 P521S
S
S
Cell line
R
S
L
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10 36149962 N61Q
S
S
Cell line
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11 36149962 N801Q
S
S
Cell line
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12 36149962 D614G
S
S
Cell line
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13 36149962 N603Q
S
S
Cell line
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14 36149962 N616Q
S
S
Cell line
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15 37529147 T19I
S
S
COVID-19
G
R
S
L
View
16 36149962 N657Q
S
S
Cell line
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17 36153659 A892P
S
S
Cell line
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18 36153659 A899P
S
S
Cell line
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19 36153659 A942P
S
S
Cell line
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20 36153659 E484K
S
S
Cell line
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21 36153659 E484Q
S
S
Cell line
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22 36153659 F817P
S
S
Cell line
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23 36153659 K417N
S
S
Cell line
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24 36153659 K417T
S
S
Cell line
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25 36153659 K986P
S
S
Cell line
View
26 39286971 P681R
S
S
COVID-19
D
G
L
View
27 36153659 L452R
S
S
Cell line
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28 36153659 R683A
S
S
Cell line
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29 36153659 R685A
S
S
Cell line
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30 36153659 T478K
S
S
Cell line
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31 36153659 V987P
S
S
Cell line
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32 36204651 D614G
S
S
Cell line
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33 36563151 D614G
S
S
Cell line
R
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34 36590900 N317P
S
S
Cell line
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35 37809871 L452Q
S
S
Cell line
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36 37809871 L452R
S
S
Cell line
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37 39772187 A27S
S
S
COVID-19
G
L
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38 37809871 F490S
S
S
Cell line
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39 37809871 N501N
S
S
Cell line
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40 37809871 N501Y
S
S
Cell line
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41 37809871 S477N
S
S
Cell line
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42 37809871 Y453F
S
S
Cell line
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43 37929963 D614G
S
S
Cell line
R
T
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44 37963924 D614G
S
S
Cell line
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45 33968806 D614G
S
S
Cell line
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46 40253323 M1237I
S
S
Cell line
R
View
47 39657661 D215G
S
S
Cell line
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48 39772187 L212I
S
S
COVID-19
G
L
View
49 39657661 D614G
S
S
Cell line
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50 39657661 D80A
S
S
Cell line
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51 39657661 F486P
S
S
Cell line
I
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52 39657661 G252V
S
S
Cell line
I
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53 39657661 G339D
S
S
Cell line
I
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54 39657661 G339H
S
S
Cell line
I
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55 39657661 H655Y
S
S
Cell line
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56 39657661 R214insEPE
S
S
Cell line
I
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57 39657661 K417T
S
S
Cell line
I
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58 39657661 L368I
S
S
Cell line
I
View
59 39772187 Y145D
S
S
COVID-19
G
L
View
60 39657661 M1229I
S
S
Cell line
I
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61 39657661 N460K
S
S
Cell line
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62 39657661 P26S
S
S
Cell line
I
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63 39657661 Q677H
S
S
Cell line
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64 39657661 S477N
S
S
Cell line
I
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65 39657661 T572I
S
S
Cell line
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66 39657661 V1176F
S
S
Cell line
I
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67 39657661 V213E
S
S
Cell line
I
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68 39657661 V445P
S
S
Cell line
I
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69 39657661 Y453F
S
S
Cell line
I
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70 39881253 G446S
S
S
COVID-19
G
L
View
71 38548763 T323I
S
S
Cell line
I
L
View
72 38548763 K529N
S
S
Cell line
I
L
View
73 38548763 T547I
S
S
Cell line
I
L
View
74 38548763 T547K
S
S
Cell line
I
L
View
75 38548763 E554K
S
S
Cell line
I
L
View
76 38548763 N556K
S
S
Cell line
I
L
View
77 38548763 L560Q
S
S
Cell line
I
L
View
78 38548763 A570D
S
S
Cell line
I
L
View
79 38548763 A570V
S
S
Cell line
I
L
View
80 38548763 T572I
S
S
Cell line
I
L
View
81 36731147 Q493R
S
S
COVID-19
D
G
C
View
82 38548763 T573I
S
S
Cell line
I
L
View
83 38548763 E583D
S
S
Cell line
I
L
View
84 37382441 D614G
S
S
Cell line
R
View
85 34226895 D614G
S
S
Cell line
View
86 34226895 E484K
S
S
Cell line
View
87 34226895 K417N
S
S
Cell line
View
88 34226895 N501Y
S
S
Cell line
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89 34214467 E484D
S
S
Cell line
R
S
View
90 34228597 D614G
S
S
Cell line
View
91 34228597 E484K
S
S
Cell line
I
View
92 36731147 F486V
S
S
COVID-19
D
G
C
View
93 34228597 N501Y
S
S
Cell line
I
View
94 34228597 S477N
S
S
Cell line
I
View
95 34985974 D614G
S
S
Cell line
View
96 32756549 D614G
S
S
Cell line
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97 34464596 F486P
S
S
Cell line
I
View
98 34464596 F486V
S
S
Cell line
I
View
99 34464596 G476D
S
S
Cell line
I
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100 34464596 G476S
S
S
Cell line
I
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.


SARS-CoV-2 Target Gene Info
Only show 100 info Click here to see all SARS-CoV-2 Target Gene
ID Target gene Virus Impact Literature Count Description Detail
1 ACE2 SARS-CoV-2
M
28
E
View
2 ADAM9 SARS-CoV-2
M
1
E
S
C
View
3 CD8A SARS-CoV-2
M
1
E
S
View
4 COL6A1 SARS-CoV-2
M
1
E
S
View
5 DPP4 SARS-CoV-2
M
1
E
S
C
View
6 FBXL12 SARS-CoV-2
M
1
E
View
7 FCGRT SARS-CoV-2
M
1
E
S
View
8 FKBP10 SARS-CoV-2
M
1
E
S
View
9 FURIN SARS-CoV-2
M
1
E
S
C
View
10 GDF15 SARS-CoV-2
M
1
E
S
C
View
11 GIGYF2 SARS-CoV-2
M
1
E
S
C
View
12 GOLGA7 SARS-CoV-2
M
1
E
S
C
View
13 HDAC2 SARS-CoV-2
M
1
E
S
C
View
14 HLA-A SARS-CoV-2
M
1
E
S
View
15 HLA-B SARS-CoV-2
M
1
E
S
View
16 HLA-C SARS-CoV-2
M
1
E
S
View
17 HS6ST2 SARS-CoV-2
M
1
E
S
C
View
18 IFNB1 SARS-CoV-2
M
1
E
C
View
19 IL17RA SARS-CoV-2
M
1
E
S
View
20 KPNA2 SARS-CoV-2
M
1
E
S
View
21 LOX SARS-CoV-2
M
1
E
S
View
22 MARVELD2 SARS-CoV-2
M
1
E
View
23 NEU1 SARS-CoV-2
M
1
E
S
View
24 PLAT SARS-CoV-2
M
1
E
S
View
25 PLD3 SARS-CoV-2
M
1
E
S
View
26 PLOD2 SARS-CoV-2
M
1
E
S
C
View
27 RIGI SARS-CoV-2
M
1
E
C
View
28 SERINC5 SARS-CoV-2
M
1
E
S
C
View
29 TBK1 SARS-CoV-2
M
1
E
S
C
View
30 TMPRSS2 SARS-CoV-2
M
1
E
S
C
View
31 ZDHHC5 SARS-CoV-2
M
1
E
S
View
Contents Description and
Data Download
Table Note
I
Target gene is affected by virus integration.
M
Target gene is associated with the virus gene/protein/region.
E
Target gene is detected in the expression profiling data.
S
Target gene is detected in the single-cell transcriptome data.
C
Target gene is detected in the genome binding/occupancy profiling data.
M
Target gene is detected in the methylation profiling data.
F
Target gene provides figures to visualize the analysis results.
F indicates that this gene has visualization results on at least one type of sequencing data.