Overview of EBOV Mutation, Integration-Cistrome Factor Overlap and Target gene

Ebola Virus (EBOV) also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after infection. The first symptoms are usually fever, sore throat, muscle pain, and headaches. These are usually followed by vomiting, diarrhoea, rash and decreased liver and kidney function, at which point some people begin to bleed both internally and externally.
Size: 19kb
Encoding: GP, L, NP, VP24, VP35, VP40, etc.
Human Disease: Hemorrhagic fever, ebola, etc.
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EBOV Mutation Info
Only show 100 info Click here to see all EBOV Mutation Sites
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 25732811 D637L
GP
GP
Hemorrhagic fever, ebola
G
View
2 38278475 P429H
GP
GP
Hemorrhagic fever, ebola
G
R
View
3 38278475 P429S
GP
GP
Hemorrhagic fever, ebola
G
R
View
4 38278475 P429L
GP
GP
Hemorrhagic fever, ebola
G
R
View
5 38278475 P429A
GP
GP
Hemorrhagic fever, ebola
G
R
View
6 38278475 P429T
GP
GP
Hemorrhagic fever, ebola
G
R
View
7 38278475 E305S
GP
GP
Hemorrhagic fever, ebola
G
R
View
8 38278475 L306C
GP
GP
Hemorrhagic fever, ebola
G
R
View
9 38278475 P430L
GP
GP
Hemorrhagic fever, ebola
G
R
View
10 38278475 P430S
GP
GP
Hemorrhagic fever, ebola
G
R
View
11 38278475 F443S
GP
GP
Hemorrhagic fever, ebola
G
R
View
12 38278475 F443A
GP
GP
Hemorrhagic fever, ebola
G
R
View
13 38278475 F443L
GP
GP
Hemorrhagic fever, ebola
G
R
View
14 38278475 L444P
GP
GP
Hemorrhagic fever, ebola
G
R
View
15 38278475 S307L
GP
GP
Hemorrhagic fever, ebola
G
R
View
16 38278475 G122S
L
L
Hemorrhagic fever, ebola
G
R
View
17 38278475 G122D
L
L
Hemorrhagic fever, ebola
G
R
View
18 38278475 T233N
L
L
Hemorrhagic fever, ebola
G
R
View
19 38278475 T233S
L
L
Hemorrhagic fever, ebola
G
R
View
20 38278475 E539G
L
L
Hemorrhagic fever, ebola
G
R
View
21 38278475 E539K
L
L
Hemorrhagic fever, ebola
G
R
View
22 38278475 D767N
L
L
Hemorrhagic fever, ebola
G
R
View
23 38278475 R1405Q
L
L
Hemorrhagic fever, ebola
G
R
View
24 38278475 V1562I
L
L
Hemorrhagic fever, ebola
G
R
View
25 38278475 V1597A
L
L
Hemorrhagic fever, ebola
G
R
View
26 38278475 F1610C
L
L
Hemorrhagic fever, ebola
G
R
View
27 38278475 F1610L
L
L
Hemorrhagic fever, ebola
G
R
View
28 38278475 Q1716P
L
L
Hemorrhagic fever, ebola
G
R
View
29 38278475 Q1716R
L
L
Hemorrhagic fever, ebola
G
R
View
30 38278475 N1739S
L
L
Hemorrhagic fever, ebola
G
R
View
31 38278475 T1772I
L
L
Hemorrhagic fever, ebola
G
R
View
32 38278475 T1772A
L
L
Hemorrhagic fever, ebola
G
R
View
33 38278475 Q1793R
L
L
Hemorrhagic fever, ebola
G
R
View
34 38278475 I1951V
L
L
Hemorrhagic fever, ebola
G
R
View
35 38278475 I2137F
L
L
Hemorrhagic fever, ebola
G
R
View
36 38278475 K163Q
VP24
VP24
Hemorrhagic fever, ebola
G
R
View
37 38278475 K163E
VP24
VP24
Hemorrhagic fever, ebola
G
R
View
38 38278475 K163R
VP24
VP24
Hemorrhagic fever, ebola
G
R
View
39 38278475 E224L
VP24
VP24
Hemorrhagic fever, ebola
G
R
View
40 38278475 R635K
NP
NP
Hemorrhagic fever, ebola
G
R
View
41 27847361 A82V
GP
GP
Hemorrhagic fever, ebola
G
S
L
View
42 34484156 A82V
GP
GP
Hemorrhagic fever, ebola
G
View
43 27847361 D759G
L
L
Hemorrhagic fever, ebola
G
S
L
View
44 34484156 D759G
L
L
Hemorrhagic fever, ebola
G
View
45 27847361 R111C
NP
NP
Hemorrhagic fever, ebola
G
S
L
View
46 34484156 R111C
NP
NP
Hemorrhagic fever, ebola
G
View
47 36946725 A82V
GP
GP
Hemorrhagic fever, ebola
R
S
View
48 36946725 E258A
GP
GP
Hemorrhagic fever, ebola
R
S
View
49 36946725 K340R
GP
GP
Hemorrhagic fever, ebola
R
S
View
50 36946725 D759G
L
L
Hemorrhagic fever, ebola
R
S
View
51 36946725 I1614T
L
L
Hemorrhagic fever, ebola
R
S
View
52 36946725 N1779S
L
L
Hemorrhagic fever, ebola
R
S
View
53 36946725 P1151S
L
L
Hemorrhagic fever, ebola
R
S
View
54 36946725 Q986H
L
L
Hemorrhagic fever, ebola
R
S
View
55 36946725 R111C
NP
NP
Hemorrhagic fever, ebola
R
S
View
56 36946725 K239Q
VP24
VP24
Hemorrhagic fever, ebola
R
S
View
57 18199658 R312A
VP35
VP35
Cell line
Hemorrhagic fever, ebola
G
I
T
View
58 20071589 K319A
VP35
VP35
Cell line
Hemorrhagic fever, ebola
G
R
T
View
59 20071589 R322A
VP35
VP35
Cell line
Hemorrhagic fever, ebola
G
R
T
View
60 23794798 M51R
M
VP40
Cell line
Hemorrhagic fever, ebola
View
61 16977667 C306G
GP
GP
Cell line
G
T
View
62 16977667 C53G
GP
GP
Cell line
G
T
View
63 35384693 A82V
GP
GP
Cell line
S
T
View
64 35384693 D552N
GP
GP
Cell line
S
I
T
View
65 35384693 K510E
GP
GP
Cell line
S
I
T
View
66 35384693 T544I
GP
GP
Cell line
S
T
View
67 24721789 A526I
GP
GP
Cell line
T
View
68 24721789 A667I
GP
GP
Cell line
T
View
69 24721789 C670A
GP
GP
Cell line
T
View
70 24721789 C672A
GP
GP
Cell line
T
View
71 24721789 F535A
GP
GP
Cell line
T
View
72 24721789 G528A
GP
GP
Cell line
T
View
73 24721789 G536A
GP
GP
Cell line
T
View
74 24721789 G655A
GP
GP
Cell line
T
View
75 24721789 I532A
GP
GP
Cell line
T
View
76 24721789 I656A
GP
GP
Cell line
T
View
77 24721789 I666A
GP
GP
Cell line
T
View
78 24721789 L668A
GP
GP
Cell line
T
View
79 24721789 P533A
GP
GP
Cell line
T
View
80 24721789 P537A
GP
GP
Cell line
T
View
81 24721789 W531A
GP
GP
Cell line
T
View
82 32098814 R26A
VP30
VP30
Cell line
T
View
83 40186866 A82V
GP
GP
Cell line
T
View
84 37333330 E619K
NP
NP
Cell line
R
T
View
85 33593971 A82V
GP
GP
Cell line
D
G
R
T
View
86 28084671 A82V
GP
GP
Cell line
G
S
T
View
87 31289183 R64A
GP
GP
Cell line
D
G
R
T
View
88 28238624 A82V
GP
GP
Cell line
G
R
T
View
89 27814506 A82V
GP
GP
Cell line
G
R
T
View
90 33593971 T544I
GP
GP
Cell line
D
G
R
T
View
91 22378924 Y13A
VP40
VP40
Cell line
T
View
92 18353943 R312A
VP35
VP35
Cell line
G
I
T
View
93 37243162 N135A
VP24
VP24
Cell line
T
View
94 37243162 N135Q
VP24
VP24
Cell line
T
View
95 37243162 P83A
VP24
VP24
Cell line
T
View
96 37243162 P83S
VP24
VP24
Cell line
T
View
97 37243162 R140A
VP24
VP24
Cell line
T
View
98 37243162 R140H
VP24
VP24
Cell line
T
View
99 37243162 V141A
VP24
VP24
Cell line
T
View
100 37243162 V141G
VP24
VP24
Cell line
T
View
Contents
Description

The table shows all curated mutation sites of EBOV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.


EBOV Target Gene Info
Only show 100 info Click here to see all EBOV Target Gene
ID Target gene Virus Impact Literature Count Description Detail
1 BST2 EBOV
M
1
E
View
2 CCL2 EBOV
M
1
E
View
3 CCL3 EBOV
M
1
E
View
4 CCL4 EBOV
M
1
E
View
5 CCL5 EBOV
M
1
E
View
6 CSF3 EBOV
M
1
E
View
7 CTSL EBOV
M
1
E
View
8 CXCL1 EBOV
M
1
E
View
9 CXCL10 EBOV
M
1
E
View
10 EIF2S1 EBOV
M
1
E
View
11 HAVCR1 EBOV
M
1
E
View
12 HLA-A EBOV
M
1
E
View
13 IFIH1 EBOV
M
1
E
View
14 IFIT1 EBOV
M
1
E
View
15 IFIT2 EBOV
M
1
E
View
16 IFIT3 EBOV
M
1
E
View
17 IFNA1 EBOV
M
3
E
View
18 IFNB1 EBOV
M
4
E
View
19 IFNG EBOV
M
1
E
View
20 IKBKE EBOV
M
1
E
View
21 IL15 EBOV
M
1
E
View
22 IL15RA EBOV
M
1
E
View
23 IL1B EBOV
M
1
E
View
24 IL22 EBOV
M
1
E
View
25 IL6 EBOV
M
1
E
View
26 IRF3 EBOV
M
1
E
View
27 IRF9 EBOV
M
1
E
View
28 ISG15 EBOV
M
1
E
View
29 KPNA1 EBOV
M
1
E
View
30 KPNA5 EBOV
M
3
E
View
31 KPNA6 EBOV
M
1
E
View
32 MAVS EBOV
M
1
E
View
33 MX1 EBOV
M
1
E
View
34 NEDD4 EBOV
M
1
E
View
35 NPC1 EBOV
M
7
E
View
36 PPA1 EBOV
M
2
E
View
37 RAN EBOV
M
1
E
View
38 RIGI EBOV
M
2
E
View
39 SIRT1 EBOV
M
1
E
View
40 SMOC1 EBOV
M
1
E
View
41 SRPK1 EBOV
M
1
E
View
42 STAT1 EBOV
M
2
E
View
43 TBK1 EBOV
M
1
E
View
44 TNF EBOV
M
1
E
View
Contents Description and
Data Download
Table Note
I
Target gene is affected by virus integration.
M
Target gene is associated with the virus gene/protein/region.
E
Target gene is detected in the expression profiling data.
S
Target gene is detected in the single-cell transcriptome data.
C
Target gene is detected in the genome binding/occupancy profiling data.
M
Target gene is detected in the methylation profiling data.
F
Target gene provides figures to visualize the analysis results.
F indicates that this gene has visualization results on at least one type of sequencing data.