Overview of ZIKV Mutation, Integration-Cistrome Factor Overlap and Target gene

Zika Virus (ZIKV) is a member of the virus family Flaviviridae. It is spread by daytime-active Aedes mosquitoes, such as A. aegypti and A. albopictus. Zika virus shares a genus with the dengue, yellow fever, Japanese encephalitis, and West Nile viruses.
Size: 11kb
Encoding: C, E, M, NS1, NS2A, NS2B, NS3, NS4B, NS5, prM, FWR, etc.
Human Disease: Guillain-Barre Syndrome, Microcephaly, etc.
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ZIKV Mutation Info
Only show 100 info Click here to see all ZIKV Mutation Sites
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37891235 T106A
C
capsid
Zika virus infection
G
R
S
L
View
2 37891235 V473M
E
envelope
Zika virus infection
G
R
S
L
View
3 37891235 A188V
NS1
NS1
Zika virus infection
G
R
S
L
View
4 37891235 M872V
NS5
NS5
Zika virus infection
G
R
S
L
View
5 37891235 V1A
prM
prM
Zika virus infection
G
R
S
L
View
6 28876359 A188V
NS1
NS1
Zika virus infection
G
View
7 29746837 K399R
NS3
NS3
Zika virus infection
S
View
8 29746837 G18R
NS4B
NS4B
Zika virus infection
S
T
View
9 35336887 H355Y
NS3
NS3
Zika virus infection
G
R
L
View
10 35336887 A310E
E
envelope
Zika virus infection
G
R
L
View
11 35336887 E393K
E
envelope
Zika virus infection
G
R
L
View
12 28539654 V2261A
2K
Zika virus infection
R
S
C
L
View
13 28539654 V2261G
2K
Zika virus infection
R
S
C
L
View
14 28539654 U6889C
2K
Zika virus infection
R
S
C
L
View
15 28539654 U6889G
2K
Zika virus infection
R
S
C
L
View
16 28539654 L307F
E
envelope
Zika virus infection
R
S
C
L
View
17 28539654 G1898U
E
envelope
Zika virus infection
R
S
C
L
View
18 28539654 A1116G
E
envelope
Zika virus infection
R
S
C
L
View
19 28539654 G1522U
E
envelope
Zika virus infection
R
S
C
L
View
20 28539654 G1820A
E
envelope
Zika virus infection
R
S
C
L
View
21 28539654 G1820C
E
envelope
Zika virus infection
R
S
C
L
View
22 28539654 T337V
E
envelope
Zika virus infection
R
S
C
L
View
23 28539654 G472V
E
envelope
Zika virus infection
R
S
C
L
View
24 28539654 K571K
E
envelope
Zika virus infection
R
S
C
L
View
25 28539654 K571N
E
envelope
Zika virus infection
R
S
C
L
View
26 28539654 L597F
E
envelope
Zika virus infection
R
S
C
L
View
27 28539654 C834U
M
prM
Zika virus infection
R
S
C
L
View
28 28539654 C917A
M
prM
Zika virus infection
R
S
C
L
View
29 28539654 C970U
M
prM
Zika virus infection
R
S
C
L
View
30 28539654 U972C
M
prM
Zika virus infection
R
S
C
L
View
31 28539654 H243Y
M
prM
Zika virus infection
R
S
C
L
View
32 28539654 S270R
M
prM
Zika virus infection
R
S
C
L
View
33 28539654 A288V
M
prM
Zika virus infection
R
S
C
L
View
34 28539654 Y289H
M
prM
Zika virus infection
R
S
C
L
View
35 28539654 M220V
NS1
NS1
Zika virus infection
R
S
C
L
View
36 28539654 U2758C
NS1
NS1
Zika virus infection
R
S
C
L
View
37 28539654 C2774A
NS1
NS1
Zika virus infection
R
S
C
L
View
38 28539654 U2781C
NS1
NS1
Zika virus infection
R
S
C
L
View
39 28539654 C2808A
NS1
NS1
Zika virus infection
R
S
C
L
View
40 28539654 C2808U
NS1
NS1
Zika virus infection
R
S
C
L
View
41 28539654 C2851U
NS1
NS1
Zika virus infection
R
S
C
L
View
42 28539654 A3061G
NS1
NS1
Zika virus infection
R
S
C
L
View
43 28539654 A3147G
NS1
NS1
Zika virus infection
R
S
C
L
View
44 28539654 V884A
NS1
NS1
Zika virus infection
R
S
C
L
View
45 28539654 N889K
NS1
NS1
Zika virus infection
R
S
C
L
View
46 28539654 W892R
NS1
NS1
Zika virus infection
R
S
C
L
View
47 28539654 P901T
NS1
NS1
Zika virus infection
R
S
C
L
View
48 28539654 P901S
NS1
NS1
Zika virus infection
R
S
C
L
View
49 28539654 S915L
NS1
NS1
Zika virus infection
R
S
C
L
View
50 28539654 K985R
NS1
NS1
Zika virus infection
R
S
C
L
View
51 28539654 M1014V
NS1
NS1
Zika virus infection
R
S
C
L
View
52 28539654 G3798C
NS2A
NS2A
Zika virus infection
R
S
C
L
View
53 28539654 V1231L
NS2A
NS2A
Zika virus infection
R
S
C
L
View
54 28539654 C4437U
NS2B
NS2B
Zika virus infection
R
S
C
L
View
55 28539654 P1444S
NS2B
NS2B
Zika virus infection
R
S
C
L
View
56 28539654 A5306U
NS3
NS3
Zika virus infection
R
S
C
L
View
57 28539654 G5312U
NS3
NS3
Zika virus infection
R
S
C
L
View
58 28539654 A6336G
NS3
NS3
Zika virus infection
R
S
C
L
View
59 28539654 E1733D
NS3
NS3
Zika virus infection
R
S
C
L
View
60 28539654 E1735D
NS3
NS3
Zika virus infection
R
S
C
L
View
61 28539654 S2077G
NS3
NS3
Zika virus infection
R
S
C
L
View
62 28539654 C7885A
NS5
NS5
Zika virus infection
R
S
C
L
View
63 28539654 A8185G
NS5
NS5
Zika virus infection
R
S
C
L
View
64 28539654 C8765A
NS5
NS5
Zika virus infection
R
S
C
L
View
65 28539654 C8765U
NS5
NS5
Zika virus infection
R
S
C
L
View
66 28539654 G8934A
NS5
NS5
Zika virus infection
R
S
C
L
View
67 28539654 G8934U
NS5
NS5
Zika virus infection
R
S
C
L
View
68 28539654 C8935U
NS5
NS5
Zika virus infection
R
S
C
L
View
69 28539654 U9219C
NS5
NS5
Zika virus infection
R
S
C
L
View
70 28539654 U9219G
NS5
NS5
Zika virus infection
R
S
C
L
View
71 28539654 P2593H
NS5
NS5
Zika virus infection
R
S
C
L
View
72 28539654 E2693G
NS5
NS5
Zika virus infection
R
S
C
L
View
73 28539654 D2886E
NS5
NS5
Zika virus infection
R
S
C
L
View
74 28539654 D2886D
NS5
NS5
Zika virus infection
R
S
C
L
View
75 28539654 A2943T
NS5
NS5
Zika virus infection
R
S
C
L
View
76 28539654 A2943S
NS5
NS5
Zika virus infection
R
S
C
L
View
77 28539654 A2943V
NS5
NS5
Zika virus infection
R
S
C
L
View
78 28539654 Y3038H
NS5
NS5
Zika virus infection
R
S
C
L
View
79 28539654 Y3038D
NS5
NS5
Zika virus infection
R
S
C
L
View
80 35891552 E143K
prM
prM
Microcephaly
Cell line
G
R
View
81 35891552 N139S
prM
prM
Microcephaly
Cell line
G
R
View
82 28198446 T233A
NS1
NS1
Microcephaly
R
S
View
83 30002446 M2634V
NS5
NS5
Microcephaly
R
L
View
84 30002446 V2634M
NS5
NS5
Microcephaly
R
L
T
View
85 28971967 S139N
prM
prM
Microcephaly
View
86 39599819 K394A
E
envelope
Guillain-Barre Syndrome
G
C
L
View
87 39599819 N154A
E
envelope
Guillain-Barre Syndrome
G
C
L
View
88 39599819 Q77A
E
envelope
Guillain-Barre Syndrome
G
C
L
View
89 39599819 D67N
E
envelope
Guillain-Barre Syndrome
G
C
L
View
90 39599819 A69T
E
envelope
Guillain-Barre Syndrome
G
C
L
View
91 39561198 C4167T Guillain-Barre Syndrome
G
R
S
L
View
92 39561198 A248V
E
envelope
Guillain-Barre Syndrome
G
R
S
L
View
93 39561198 V330L
E
envelope
Guillain-Barre Syndrome
G
R
S
L
View
94 39561198 E142K
NS1
NS1
Guillain-Barre Syndrome
G
R
S
L
View
95 39561198 R276Q
NS1
NS1
Guillain-Barre Syndrome
G
R
S
L
View
96 39561198 R324W
NS1
NS1
Guillain-Barre Syndrome
G
R
S
L
View
97 39561198 I115T
NS3
NS3
Guillain-Barre Syndrome
G
R
S
L
View
98 39561198 I283V
NS3
NS3
Guillain-Barre Syndrome
G
R
S
L
View
99 39561198 S356F
NS3
NS3
Guillain-Barre Syndrome
G
R
S
L
View
100 39561198 T25A
NS4B
NS4B
Guillain-Barre Syndrome
G
R
S
L
View
Contents
Description

The table shows all curated mutation sites of ZIKV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.


ZIKV Target Gene Info
Only show 100 info Click here to see all ZIKV Target Gene
ID Target gene Virus Impact Literature Count Description Detail
1 ALDOA ZIKV
M
1
E
C
View
2 ATF4 ZIKV
M
1
E
C
View
3 AXL ZIKV
M
1
E
C
View
4 CD8A ZIKV
M
1
E
C
View
5 DICER1 ZIKV
M
2
E
C
View
6 FCGR2A ZIKV
M
1
E
C
View
7 IFNA1 ZIKV
M
1
E
C
View
8 IFNB1 ZIKV
M
1
E
C
View
9 IKBKE ZIKV
M
1
E
C
View
10 IRF3 ZIKV
M
1
E
C
View
11 KPNA2 ZIKV
M
1
E
C
View
12 NUPR1 ZIKV
M
1
E
C
View
13 PDCD1 ZIKV
M
1
E
C
View
14 PDCD1LG2 ZIKV
M
1
E
C
View
15 PDIA3 ZIKV
M
1
E
C
View
16 RPSA ZIKV
M
1
E
C
View
17 STAT2 ZIKV
M
3
E
C
View
18 TBK1 ZIKV
M
1
E
C
View
19 TLR3 ZIKV
M
1
E
C
View
20 TRAPPC1 ZIKV
M
1
E
View
Contents Description and
Data Download
Table Note
I
Target gene is affected by virus integration.
M
Target gene is associated with the virus gene/protein/region.
E
Target gene is detected in the expression profiling data.
S
Target gene is detected in the single-cell transcriptome data.
C
Target gene is detected in the genome binding/occupancy profiling data.
M
Target gene is detected in the methylation profiling data.
F
Target gene provides figures to visualize the analysis results.
F indicates that this gene has visualization results on at least one type of sequencing data.