Overview of HTLV1 Mutation, Integration-Cistrome Factor Overlap and Target gene

Human T-lymphotropic Virus 1 (HTLV1) is a retrovirus of the human T-lymphotropic virus (HTLV) family. The most well characterized are adult T-cell lymphoma (ATL) and HTLV-I-associated myelopathy/Tropical spastic paraparesis (HAM/TSP), both of which are only diagnosed in individuals testing positive to HTLV-1 infection.
Size: 9kb
Encoding: env, tax, gag, gp46, HBZ, LTR, TRE, ORF-I, p12, p30, rex, pX, etc.
Human Disease: Paraparesis, Tropical Spastic, Leukemia-Lymphoma, Adult T-Cell, etc.
Click the View button on the page to view detailed information.


HTLV1 Mutation Info
Only show 100 info Click here to see all HTLV1 Mutation Sites
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 28420387 C5593A
env
env
Paraparesis, Tropical Spastic
G
R
S
C
View
2 28420387 F19L
env
env
Paraparesis, Tropical Spastic
G
R
S
C
View
3 28420387 H137Q
env
env
Paraparesis, Tropical Spastic
G
R
S
C
View
4 28420387 S304N
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
5 28420387 T5237C
env
env
Paraparesis, Tropical Spastic
G
R
S
C
View
6 28420387 A221V
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
7 28420387 S13P
HBZ
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
8 28420387 C6903T
p12
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
9 28420387 P23S
p12
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
10 28420387 A149T
p30
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
11 28420387 A7247G
p30
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
12 28420387 D140G
p30
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
13 28420387 G7273A
p30
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
14 28420387 L27R
p30
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
15 28420387 T6908G
p30
pX
Paraparesis, Tropical Spastic
G
R
S
C
View
16 28420387 A3963T
pol
pol
Paraparesis, Tropical Spastic
G
R
S
C
View
17 28420387 Q323H
pol
pol
Paraparesis, Tropical Spastic
G
R
S
C
View
18 28420387 C7962T
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
19 28420387 G8211A
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
20 34494950 A221V
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
21 34494950 C7401T
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
22 34494950 C7920T
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
23 34494950 C7974T
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
24 34494950 C7982T
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
25 34494950 G8231A
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
26 34494950 S304N
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
27 34494950 T7914C
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
28 34494950 T8313C
tax
tax
Paraparesis, Tropical Spastic
G
R
S
C
View
29 34494950 A125G
TRE
Paraparesis, Tropical Spastic
G
R
S
C
View
30 34494950 G174A
TRE
Paraparesis, Tropical Spastic
G
R
S
C
View
31 23800288 Y477H
env
env
Paraparesis, Tropical Spastic
R
S
C
L
View
32 23510700 C289R
gp46
env
Paraparesis, Tropical Spastic
S
L
View
33 23510700 D197N
gp46
env
Paraparesis, Tropical Spastic
S
L
View
34 23510700 F141S
gp46
env
Paraparesis, Tropical Spastic
S
L
View
35 23510700 F14S
gp46
env
Paraparesis, Tropical Spastic
S
L
View
36 23510700 F159S
gp46
env
Paraparesis, Tropical Spastic
S
L
View
37 23510700 G72S
gp46
env
Paraparesis, Tropical Spastic
S
L
View
38 23510700 H290D
gp46
env
Paraparesis, Tropical Spastic
S
L
View
39 23510700 N42H
gp46
env
Paraparesis, Tropical Spastic
S
L
View
40 23510700 S35L
gp46
env
Paraparesis, Tropical Spastic
S
L
View
41 23510700 V247I
gp46
env
Paraparesis, Tropical Spastic
S
L
View
42 23800288 C101T
HBZ
pX
Paraparesis, Tropical Spastic
R
S
C
L
View
43 23800288 C336T
HBZ
pX
Paraparesis, Tropical Spastic
R
S
C
L
View
44 23800288 R112C
HBZ
pX
Paraparesis, Tropical Spastic
R
S
C
L
View
45 23800288 S9P
HBZ
pX
Paraparesis, Tropical Spastic
R
S
C
L
View
46 23800288 T95I
HBZ
pX
Paraparesis, Tropical Spastic
R
S
C
L
View
47 27553711 C39R
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
48 27553711 D26N
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
49 27553711 F61L
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
50 27553711 G29S
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
51 27553711 L40F
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
52 27553711 L66P
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
53 27553711 P34L
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
54 27553711 P45L
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
55 27553711 P91S
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
56 27553711 R83C
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
57 27553711 R88K
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
58 27553711 S23P
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
59 27553711 S63P
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
60 27553711 S69G
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
61 27553711 S91P
ORF-I
ORF-I
Paraparesis, Tropical Spastic
S
L
View
62 23800288 P34L
pX
pX
Paraparesis, Tropical Spastic
R
S
C
L
View
63 26472535 151_161del Paraparesis, Tropical Spastic
S
L
View
64 26472535 A207G Paraparesis, Tropical Spastic
S
L
View
65 26472535 A298G Paraparesis, Tropical Spastic
S
L
View
66 26472535 C167T Paraparesis, Tropical Spastic
S
L
View
67 26472535 C215T Paraparesis, Tropical Spastic
S
L
View
68 26472535 C219G Paraparesis, Tropical Spastic
S
L
View
69 26472535 C219T Paraparesis, Tropical Spastic
S
L
View
70 26472535 C268T Paraparesis, Tropical Spastic
S
L
View
71 26472535 C479T Paraparesis, Tropical Spastic
S
L
View
72 26472535 G126C Paraparesis, Tropical Spastic
S
L
View
73 26472535 G126T Paraparesis, Tropical Spastic
S
L
View
74 26472535 G153A Paraparesis, Tropical Spastic
S
L
View
75 26472535 G199A Paraparesis, Tropical Spastic
S
L
View
76 26472535 G306A Paraparesis, Tropical Spastic
S
L
View
77 26472535 G306C Paraparesis, Tropical Spastic
S
L
View
78 26472535 T165C Paraparesis, Tropical Spastic
S
L
View
79 26472535 T301A Paraparesis, Tropical Spastic
S
L
View
80 26472535 T301C Paraparesis, Tropical Spastic
S
L
View
81 26472535 T345C Paraparesis, Tropical Spastic
S
L
View
82 8011162 G7337A
pX
pX
Leukemia-Lymphoma, Adult T-Cell
Paraparesis, Tropical Spastic
Cell line
R
L
View
83 22449200 A2661V
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
84 22449200 A7722G
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
85 22449200 A8001G
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
86 22449200 A8002G
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
87 22449200 A8109G
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
88 22449200 A8288G
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
89 22449200 A8367C
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
90 22449200 C7401T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
91 22449200 C7410A
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
92 22449200 C7593T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
93 22449200 C7920T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
94 22449200 C7953T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
95 22449200 C7974T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
96 22449200 C7982T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
97 22449200 C8066G
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
98 22449200 C8184T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
99 22449200 C8191T
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
100 22449200 G7431A
tax
tax
HTLV-1-HIV Coinfection
R
S
L
View
Contents
Description

The table shows all curated mutation sites of HTLV1 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.

HTLV1 Overlap Info between Viral Integration Fragments and Cistrome Factors
Only show 100 info Click here to see all HTLV1 Integration Sites
DVID Chromosome Histone Modification Transcription Factor Binding Site Chromatin Accessibility Sum of Overlapped Records Detail
6033624 chr1 3940 9486 2116 15542 View
6033566 chr1 3854 9474 2113 15441 View
6033622 chr1 2350 7942 2090 12382 View
6033918 chr1 4522 2460 1276 8258 View
6000031 chr1 3978 2549 1464 7991 View
6000047 chr1 4112 1394 1021 6527 View
6000054 chr1 3675 1747 732 6154 View
6000063 chr1 2791 1709 1282 5782 View
6000065 chr1 996 2628 2080 5704 View
6000066 chr1 4167 1076 439 5682 View
6000070 chr1 2539 1638 1377 5554 View
6000071 chr1 2602 1746 1205 5553 View
6000085 chr1 3060 1258 767 5085 View
6000086 chr1 2566 1546 945 5057 View
6000087 chr1 2445 1002 1583 5030 View
6000105 chr1 1309 1601 1675 4585 View
6000107 chr1 2439 1021 1090 4550 View
6033637 chr1 3251 717 348 4316 View
6000121 chr1 3278 664 294 4236 View
6000124 chr1 2165 1391 628 4184 View
6000154 chr1 2440 605 619 3664 View
6000159 chr1 3139 242 214 3595 View
6000162 chr1 2254 768 529 3551 View
6000167 chr1 2939 368 141 3448 View
6000171 chr1 3066 207 114 3387 View
6000177 chr1 2330 519 459 3308 View
6000179 chr1 885 1158 1255 3298 View
6000192 chr1 2047 939 174 3160 View
6000220 chr1 2711 122 70 2903 View
6000222 chr1 2374 193 317 2884 View
6000233 chr1 2247 293 191 2731 View
6000242 chr1 2551 81 29 2661 View
6000240 chr1 2469 115 75 2659 View
6000256 chr1 2010 316 246 2572 View
6000259 chr1 2423 93 9 2525 View
6000267 chr1 2107 295 74 2476 View
6000285 chr1 1819 302 226 2347 View
6000304 chr1 603 857 781 2241 View
6000308 chr1 2124 39 29 2192 View
6000315 chr1 2107 37 4 2148 View
6000322 chr1 1396 343 393 2132 View
6000323 chr1 1758 210 155 2123 View
6000325 chr1 56 1088 969 2113 View
6000329 chr1 1857 121 117 2095 View
6000332 chr1 1513 257 307 2077 View
6000341 chr1 408 872 755 2035 View
6000349 chr1 1778 96 138 2012 View
6000358 chr1 1784 198 9 1991 View
6033629 chr1 1225 444 273 1942 View
6000383 chr1 611 503 715 1829 View
6000384 chr1 96 1025 701 1822 View
6000396 chr1 1224 256 286 1766 View
6000401 chr1 368 674 703 1745 View
6000411 chr1 1027 366 313 1706 View
6000442 chr1 1257 135 200 1592 View
6000456 chr1 1117 256 185 1558 View
6000464 chr1 7 915 590 1512 View
6000486 chr1 1130 186 127 1443 View
6000487 chr1 592 460 383 1435 View
6000500 chr1 318 477 612 1407 View
6000505 chr1 516 679 201 1396 View
6000512 chr1 282 443 636 1361 View
6000515 chr1 30 794 531 1355 View
6000578 chr1 959 117 122 1198 View
6000614 chr1 772 321 35 1128 View
6000617 chr1 29 655 442 1126 View
6000619 chr1 138 433 541 1112 View
6000668 chr1 899 69 31 999 View
6000680 chr1 682 161 151 994 View
6000688 chr1 45 692 241 978 View
6000690 chr1 13 667 296 976 View
6033623 chr1 184 534 221 939 View
6000716 chr1 788 59 87 934 View
6033565 chr1 181 529 199 909 View
6000758 chr1 753 68 60 881 View
6000764 chr1 278 333 265 876 View
6000783 chr1 534 160 166 860 View
6000790 chr1 789 56 8 853 View
6000810 chr1 340 282 211 833 View
6000821 chr1 448 315 54 817 View
6000826 chr1 620 61 132 813 View
6000841 chr1 485 222 92 799 View
6000842 chr1 787 11
0
798 View
6000866 chr1 485 179 101 765 View
6000874 chr1 619 39 103 761 View
6000903 chr1 10 564 155 729 View
6000944 chr1 659 32 4 695 View
6000955 chr1 680 4
0
684 View
6000978 chr1 639 22
0
661 View
6000987 chr1 42 242 372 656 View
6000990 chr1 550 48 57 655 View
6000991 chr1 43 242 370 655 View
6001032 chr1 16 526 94 636 View
6001033 chr1 200 159 276 635 View
6001034 chr1 465 131 31 627 View
6001061 chr1 475 78 56 609 View
6001103 chr1 389 64 130 583 View
6001109 chr1 337 161 81 579 View
6001123 chr1 34 379 164 577 View
6001133 chr1 415 50 106 571 View

Click to see histogram of VIS-Factor Overlap by chromosome of HTLV1

Click to see the overlap count of three factors and HTLV1 intergration fragments on the human chromosomes


HTLV1 Target Gene Info
Only show 100 info Click here to see all HTLV1 Target Gene
ID Target gene Virus Impact Literature Count Description Detail
1 A2ML1 HTLV1
I
1
E
C
M
View
2 A4GALT HTLV1
I
3
E
C
M
View
3 A4GNT HTLV1
I
1
E
C
M
View
4 AACS HTLV1
I
1
E
C
M
View
5 AACSP1 HTLV1
I
1
E
C
M
View
6 AADACL2-AS1 HTLV1
I
1
C
M
View
7 AADAT HTLV1
I
1
E
C
M
View
8 AAGAB HTLV1
I
2
E
C
M
View
9 AAK1 HTLV1
I
2
E
C
M
View
10 AAMDC HTLV1
I
2
E
C
M
View
11 AATF HTLV1
I
1
E
C
M
View
12 ABAT HTLV1
I
1
E
C
M
View
13 ABCA1 HTLV1
I
2
E
C
M
View
14 ABCA13 HTLV1
I
2
E
C
M
View
15 ABCA17P HTLV1
I
1
E
C
M
View
16 ABCA2 HTLV1
I
1
E
C
M
View
17 ABCA4 HTLV1
I
1
E
C
M
View
18 ABCA5 HTLV1
I
2
E
C
M
View
19 ABCB1 HTLV1
I
1
E
C
M
View
20 ABCB4 HTLV1
I
2
E
C
M
View
21 ABCB5 HTLV1
I
1
E
C
M
View
22 ABCB7 HTLV1
I
1
E
C
M
View
23 ABCB9 HTLV1
I
1
E
C
M
View
24 ABCC1 HTLV1
I
2
E
C
M
View
25 ABCC11 HTLV1
I
3
E
C
M
View
26 ABCC12 HTLV1
I
1
E
C
M
View
27 ABCC13 HTLV1
I
2
E
C
M
View
28 ABCC3 HTLV1
I
1
E
C
M
View
29 ABCC4 HTLV1
I
3
E
C
M
View
30 ABCC5 HTLV1
I
2
E
C
M
View
31 ABCC8 HTLV1
I
2
E
C
M
View
32 ABCC9 HTLV1
I
1
E
C
M
View
33 ABCD2 HTLV1
I
1
E
C
M
View
34 ABCD3 HTLV1
I
1
E
C
M
View
35 ABCF2 HTLV1
I
1
E
C
M
View
36 ABCG1 HTLV1
I
2
E
C
M
View
37 ABHD10 HTLV1
I
1
E
C
M
View
38 ABHD12 HTLV1
I
1
E
C
M
View
39 ABHD17A HTLV1
I
1
E
C
View
40 ABHD18 HTLV1
I
1
E
C
View
41 ABHD2 HTLV1
I
1
E
C
M
View
42 ABHD3 HTLV1
I
1
E
C
M
View
43 ABHD6 HTLV1
I
1
E
C
M
View
44 ABHD8 HTLV1
I
1
E
C
M
View
45 ABI1 HTLV1
I
1
E
C
M
View
46 ABI2 HTLV1
I
1
E
C
M
View
47 ABI3BP HTLV1
I
3
E
C
M
View
48 ABITRAM HTLV1
I
2
E
C
View
49 ABL2 HTLV1
I
2
E
C
M
View
50 ABLIM1 HTLV1
I
4
E
C
M
View
51 ABLIM2 HTLV1
I
2
E
C
M
View
52 ABLIM3 HTLV1
I
1
E
C
M
View
53 ABR HTLV1
I
2
E
C
M
View
54 ABRA HTLV1
I
1
E
C
M
View
55 ABTB1 HTLV1
I
1
E
C
M
View
56 ABTB2 HTLV1
I
2
E
C
M
View
57 ABTB3 HTLV1
I
3
E
C
View
58 ACAA2 HTLV1
I
1
E
C
M
View
59 ACACA HTLV1
I
2
E
C
M
View
60 ACACB HTLV1
I
1
E
C
M
View
61 ACAD10 HTLV1
I
1
E
C
M
View
62 ACAD9 HTLV1
I
1
E
C
M
View
63 ACAP1 HTLV1
I
1
E
C
M
View
64 ACBD3 HTLV1
I
1
E
C
M
View
65 ACBD5 HTLV1
I
1
E
C
M
View
66 ACBD6 HTLV1
I
1
E
C
M
View
67 ACCS HTLV1
I
1
E
C
M
View
68 ACE2 HTLV1
I
1
E
C
M
View
69 ACER2 HTLV1
I
1
E
C
M
View
70 ACER3 HTLV1
I
1
E
C
M
View
71 ACIN1 HTLV1
I
1
E
C
M
View
72 ACO2 HTLV1
I
2
E
C
M
View
73 ACOT12 HTLV1
I
1
E
C
M
View
74 ACOT13 HTLV1
I
1
E
C
M
View
75 ACOT7 HTLV1
I
1
E
C
M
View
76 ACOX2 HTLV1
I
1
E
C
M
View
77 ACOX3 HTLV1
I
2
E
C
M
View
78 ACOXL HTLV1
I
1
E
C
M
View
79 ACP1 HTLV1
I
1
E
C
M
View
80 ACP5 HTLV1
I
1
E
C
M
View
81 ACP6 HTLV1
I
1
E
C
M
View
82 ACSBG1 HTLV1
I
1
E
C
M
View
83 ACSL3 HTLV1
I
1
E
C
M
View
84 ACSL4 HTLV1
I
1
E
C
M
View
85 ACSL6 HTLV1
I
1
E
C
M
View
86 ACSM1 HTLV1
I
1
E
C
M
View
87 ACSM2A HTLV1
I
1
E
C
M
View
88 ACSM2B HTLV1
I
1
E
C
M
View
89 ACSS1 HTLV1
I
1
E
C
M
View
90 ACSS2 HTLV1
I
1
E
C
M
View
91 ACSS3 HTLV1
I
2
E
C
M
View
92 ACTA2 HTLV1
I
2
E
C
M
View
93 ACTA2-AS1 HTLV1
I
1
E
C
M
View
94 ACTB HTLV1
I
1
E
C
M
View
95 ACTE1P HTLV1
I
1
E
C
View
96 ACTG1 HTLV1
I
1
E
C
M
View
97 ACTL8 HTLV1
I
1
E
C
M
View
98 ACTMAP HTLV1
I
1
E
C
View
99 ACTN1 HTLV1
I
2
E
C
M
View
100 ACTR10 HTLV1
I
1
E
C
M
View
Contents Description and
Data Download
Table Note
I
Target gene is affected by virus integration.
M
Target gene is associated with the virus gene/protein/region.
E
Target gene is detected in the expression profiling data.
S
Target gene is detected in the single-cell transcriptome data.
C
Target gene is detected in the genome binding/occupancy profiling data.
M
Target gene is detected in the methylation profiling data.
F
Target gene provides figures to visualize the analysis results.
F indicates that this gene has visualization results on at least one type of sequencing data.