Overview of HCMV Mutation, Integration-Cistrome Factor Overlap and Target gene

Human Cytomegalovirus (HCMV) also called human herpesvirus 5 (HHV-5), is a species of virus in the genus Cytomegalovirus, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is also commonly called CMV. CMV is a double-stranded DNA virus.
Size: 236kb
Encoding: gB, IE2, Pol, protease, UL18, UL27, UL54, UL56, UL89, UL97, US28, etc.
Human Disease: HCMV Antigenaemia, HCMV DNAemia, Pneumonia, Enterocolitis, Cytomegalovirus Retinitis, Esophagitis, Hepatitis, Gastritis, Colitis, etc.
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HCMV Mutation Info
Only show 100 info Click here to see all HCMV Mutation Sites
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 9721800 C607Y
UL97
UL97
Cytomegalovirus infections
D
R
C
View
2 11160752 M499I
pp65
UL83
Cytomegalovirus infections
I
View
3 11505446 M460V
UL97
UL97
Cytomegalovirus infections
D
R
View
4 11888658 A594V
UL97
UL97
Cytomegalovirus infections
D
L
View
5 11888658 C592G
UL97
UL97
Cytomegalovirus infections
D
L
View
6 11888658 C607Y
UL97
UL97
Cytomegalovirus infections
D
L
View
7 11888658 G598S
UL97
UL97
Cytomegalovirus infections
D
L
View
8 11888658 H520Q
UL97
UL97
Cytomegalovirus infections
D
L
View
9 11888658 L595F
UL97
UL97
Cytomegalovirus infections
D
L
View
10 11888658 L595S
UL97
UL97
Cytomegalovirus infections
D
L
View
11 11888658 M460I
UL97
UL97
Cytomegalovirus infections
D
L
View
12 11888658 M460V
UL97
UL97
Cytomegalovirus infections
D
L
View
13 14739146 A594V
UL97
UL97
Cytomegalovirus infections
D
I
C
T
View
14 14739146 H520Q
UL97
UL97
Cytomegalovirus infections
D
I
C
T
View
15 14739146 P522S
UL54
UL54
Cytomegalovirus infections
D
I
C
T
View
16 15793144 601del
UL97
UL97
Cytomegalovirus infections
D
R
S
C
View
17 16000504 H520Q
UL97
UL97
Cytomegalovirus infections
D
C
View
18 16962820 L397R
UL97
UL97
Cytomegalovirus infections
D
View
19 17112867 D605E
UL97
UL97
Cytomegalovirus infections
R
L
View
20 17157554 D413A
Pol
UL54
Cytomegalovirus infections
D
C
View
21 17157554 M460V
UL97
UL97
Cytomegalovirus infections
D
C
View
22 17161359 A594V
UL97
UL97
Cytomegalovirus infections
S
C
L
View
23 17161359 A595F
UL97
UL97
Cytomegalovirus infections
S
C
L
View
24 17161359 L595F
UL97
UL97
Cytomegalovirus infections
S
C
L
View
25 17161359 L595S
UL97
UL97
Cytomegalovirus infections
S
C
L
View
26 17538888 T409M
UL97
UL97
Cytomegalovirus infections
D
R
View
27 17538888 V353A
UL97
UL97
Cytomegalovirus infections
D
R
View
28 17605746 A594V
UL97
UL97
Cytomegalovirus infections
D
C
View
29 17709468 C592G
UL97
UL97
Cytomegalovirus infections
D
View
30 17709468 G841A
Pol
UL54
Cytomegalovirus infections
D
View
31 17709468 L845P
Pol
UL54
Cytomegalovirus infections
View
32 17709468 T813S
Pol
UL54
Cytomegalovirus infections
D
View
33 18419454 L776M
Pol
UL54
Cytomegalovirus infections
D
C
View
34 19147520 A594V
UL97
UL97
Cytomegalovirus infections
D
R
C
View
35 19147520 D605E
UL97
UL97
Cytomegalovirus infections
R
C
View
36 19147520 H602Y
UL97
UL97
Cytomegalovirus infections
R
C
View
37 19147520 M460V
UL97
UL97
Cytomegalovirus infections
D
R
C
View
38 19147520 M526I
UL97
UL97
Cytomegalovirus infections
R
C
View
39 19152402 C592G
UL97
UL97
Cytomegalovirus infections
D
R
C
View
40 19152402 N597D
UL97
UL97
Cytomegalovirus infections
R
C
View
41 19812447 G296S
UL44
UL44
Cytomegalovirus infections
R
View
42 19812447 L319I
UL44
UL44
Cytomegalovirus infections
R
View
43 20138805 C603R
UL97
UL97
Cytomegalovirus infections
D
R
C
View
44 20138805 M615V
UL97
UL97
Cytomegalovirus infections
D
R
C
View
45 20138805 V466G
UL97
UL97
Cytomegalovirus infections
R
C
View
46 20504236 H411Y
UL97
UL97
Cytomegalovirus infections
D
R
View
47 20504236 T409M
UL97
UL97
Cytomegalovirus infections
D
R
View
48 21070537 D485N
UL54
UL54
Cytomegalovirus infections
R
S
View
49 21070537 F412S
UL54
UL54
Cytomegalovirus infections
R
S
View
50 21199205 M460I
UL97
UL97
Cytomegalovirus infections
D
L
View
51 21199205 M460V
UL97
UL97
Cytomegalovirus infections
D
L
View
52 21362026 D605E
UL97
UL97
Cytomegalovirus infections
L
View
53 22237003 C592G
UL97
UL97
Cytomegalovirus infections
D
R
View
54 22237003 C603W
UL97
UL97
Cytomegalovirus infections
D
R
View
55 22237003 M460V
UL97
UL97
Cytomegalovirus infections
D
R
View
56 22237003 P522S
UL54
UL54
Cytomegalovirus infections
D
R
View
57 22293247 L595S
UL97
UL97
Cytomegalovirus infections
R
C
View
58 22300656 C592G
UL97
UL97
Cytomegalovirus infections
D
S
View
59 22300656 H520Q
UL97
UL97
Cytomegalovirus infections
D
S
View
60 22381918 A594T
UL97
UL97
Cytomegalovirus infections
D
C
View
61 22381918 A594V
UL97
UL97
Cytomegalovirus infections
D
C
View
62 22381918 C592G
UL97
UL97
Cytomegalovirus infections
D
C
View
63 22381918 C607S
UL97
UL97
Cytomegalovirus infections
D
C
View
64 22381918 597_600del
UL97
UL97
Cytomegalovirus infections
D
C
View
65 22381918 M460I
UL97
UL97
Cytomegalovirus infections
D
C
View
66 22381918 M460V
UL97
UL97
Cytomegalovirus infections
D
C
View
67 22664236 D534Y
UL27
UL27
Cytomegalovirus infections
D
R
View
68 22664236 H411L
UL97
UL97
Cytomegalovirus infections
R
View
69 22664236 H411N
UL97
UL97
Cytomegalovirus infections
D
R
View
70 22664236 H411Y
UL97
UL97
Cytomegalovirus infections
D
R
View
71 22664236 I324V
UL97
UL97
Cytomegalovirus infections
R
View
72 22664236 L337M
UL97
UL97
Cytomegalovirus infections
D
R
View
73 22664236 L397R
UL97
UL97
Cytomegalovirus infections
D
R
View
74 22664236 M460I
UL97
UL97
Cytomegalovirus infections
R
View
75 22664236 Q449K
UL97
UL97
Cytomegalovirus infections
R
View
76 22664236 R233S
UL27
UL27
Cytomegalovirus infections
D
R
View
77 22664236 R448P
UL27
UL27
Cytomegalovirus infections
D
R
View
78 22664236 S334G
UL97
UL97
Cytomegalovirus infections
D
R
View
79 22664236 S386L
UL97
UL97
Cytomegalovirus infections
R
View
80 22664236 V353A
UL97
UL97
Cytomegalovirus infections
D
R
View
81 22939665 A688V
UL54
UL54
Cytomegalovirus infections
R
L
View
82 22939665 A885T
UL54
UL54
Cytomegalovirus infections
R
L
View
83 22939665 D605E
UL97
UL97
Cytomegalovirus infections
R
L
View
84 22939665 N685S
UL54
UL54
Cytomegalovirus infections
R
L
View
85 22939665 N898D
UL54
UL54
Cytomegalovirus infections
R
L
View
86 23011309 C518Y
UL97
UL97
Cytomegalovirus infections
R
L
View
87 23011309 C607F
UL97
UL97
Cytomegalovirus infections
R
L
View
88 23011309 D605E
UL97
UL97
Cytomegalovirus infections
R
L
View
89 23011309 L595W
UL97
UL97
Cytomegalovirus infections
R
L
View
90 23195018 D605E
UL97
UL97
Cytomegalovirus infections
R
C
L
View
91 23195018 M406V
UL97
UL97
Cytomegalovirus infections
D
R
C
L
View
92 23198963 A594V
UL97
UL97
Cytomegalovirus infections
D
C
View
93 23198963 D605E
UL97
UL97
Cytomegalovirus infections
C
View
94 23198963 H469Y
UL97
UL97
Cytomegalovirus infections
C
View
95 23198963 N510S
UL97
UL97
Cytomegalovirus infections
C
View
96 23415883 524del
UL54
UL54
Cytomegalovirus infections
D
C
View
97 23415883 N408S
UL54
UL54
Cytomegalovirus infections
D
C
View
98 23546999 N510S
UL97
UL97
Cytomegalovirus infections
R
C
View
99 23592041 A594V
UL97
UL97
Cytomegalovirus infections
D
S
View
100 23592041 M460I
UL97
UL97
Cytomegalovirus infections
D
S
View
Contents
Description

The table shows all curated mutation sites of HCMV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.


HCMV Target Gene Info
Only show 100 info Click here to see all HCMV Target Gene
ID Target gene Virus Impact Literature Count Description Detail
1 CASP2 HCMV
M
1
E
C
View
2 CCL13 HCMV
M
1
E
C
View
3 CCL2 HCMV
M
1
E
C
View
4 CCL4 HCMV
M
1
E
C
View
5 CCL5 HCMV
M
1
E
C
View
6 CD4 HCMV
M
1
E
C
View
7 MLKL HCMV
M
1
E
C
View
8 PDGFRA HCMV
M
1
E
C
View
9 PML HCMV
M
3
E
C
View
Contents Description and
Data Download
Table Note
I
Target gene is affected by virus integration.
M
Target gene is associated with the virus gene/protein/region.
E
Target gene is detected in the expression profiling data.
S
Target gene is detected in the single-cell transcriptome data.
C
Target gene is detected in the genome binding/occupancy profiling data.
M
Target gene is detected in the methylation profiling data.
F
Target gene provides figures to visualize the analysis results.
F indicates that this gene has visualization results on at least one type of sequencing data.