Overview of EBV associated Cell line (Mutation)

ID Literature Title Group
1 23221557 Pin1 interacts with the Epstein-Barr virus DNA polymerase catalytic subunit and regulates viral DNA replication
Mutation
2 33106493 Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment
Mutation
3 16406456 Regulation of the expression of the Epstein-Barr virus early gene BFRF1
Mutation
4 20704565 Key motifs in EBV (Epstein-Barr virus)-encoded protein kinase for phosphorylation activity and nuclear localization
Mutation
5 25166506 A locus encompassing the Epstein-Barr virus bglf4 kinase regulates expression of genes encoding viral structural proteins
Mutation
6 19321754 Epstein-Barr virus protein kinase BGLF4 interacts with viral transactivator BZLF1 and regulates its transactivation activity
Mutation
7 30647152 Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation
Mutation
8 19119421 The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation
Mutation
9 21123379 The Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting major histocompatibility complex class I molecules trafficking on both the exocytic and endocytic pathways
Mutation
10 24872582 Uracil DNA glycosylase BKRF3 contributes to Epstein-Barr virus DNA replication through physical interactions with proteins in viral DNA replication complex
Mutation
11 23326445 An RS motif within the Epstein-Barr virus BLRF2 tegument protein is phosphorylated by SRPK2 and is important for viral replication
Mutation
12 20926567 Tetrameric ring formation of Epstein-Barr virus polymerase processivity factor is crucial for viral replication
Mutation
13 19394065 EBV BMRF-2 facilitates cell-to-cell spread of virus within polarized oral epithelial cells
Mutation
14 25933165 Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population
Mutation
15 19244336 The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activity
Mutation
16 38875930 Epstein-Barr virus deubiquitinating enzyme BPLF1 is involved in EBV carcinogenesis by affecting cellular genomic stability
Mutation
17 19232420 Two phenylalanines in the C-terminus of Epstein-Barr virus Rta protein reciprocally modulate its DNA binding and transactivation function
Mutation
18 22379087 Genome-wide analysis of Epstein-Barr virus Rta DNA binding
Mutation
19 21697476 Cellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latency
Mutation
20 23077295 Essential role of Rta in lytic DNA replication of Epstein-Barr virus
Mutation
21 28729695 The Epstein-Barr Virus BRRF1 Gene Is Dispensable for Viral Replication in HEK293 cells and Transformation
Mutation
22 25900136 RanBPM regulates Zta-mediated transcriptional activity in Epstein-Barr virus
Mutation
23 20808903 A subset of replication proteins enhances origin recognition and lytic replication by the Epstein-Barr virus ZEBRA protein
Mutation
24 20516063 Transcriptional repression by sumoylation of Epstein-Barr virus BZLF1 protein correlates with association of histone deacetylase
Mutation
25 18937960 Mutations of amino acids in the DNA-recognition domain of Epstein-Barr virus ZEBRA protein alter its sub-nuclear localization and affect formation of replication compartments
Mutation
26 18369464 Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein
Mutation
27 18305033 Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication
Mutation
28 15919888 BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186
Mutation
29 10559298 Role of the epstein-barr virus RTA protein in activation of distinct classes of viral lytic cycle genes
Mutation
30 24705134 Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(A)-binding protein are distinct processes mediated by two Epstein Barr virus proteins
Mutation
31 9123876 The bZip dimerization domain of the Epstein-Barr virus BZLF1 (Z) protein mediates lymphoid-specific negative regulation
Mutation
32 12388679 Disruption of Epstein-Barr virus latency in the absence of phosphorylation of ZEBRA by protein kinase C
Mutation
33 16940523 Amino acids in the basic domain of Epstein-Barr virus ZEBRA protein play distinct roles in DNA binding, activation of early lytic gene expression, and promotion of viral DNA replication
Mutation
34 17215287 Phosphoacceptor site S173 in the regulatory domain of Epstein-Barr Virus ZEBRA protein is required for lytic DNA replication but not for activation of viral early genes
Mutation
35 19325883 Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promoters
Mutation
36 21233201 Efficient induction of nuclear aggresomes by specific single missense mutations in the DNA-binding domain of a viral AP-1 homolog
Mutation
37 23625009 Latency of Epstein-Barr virus is disrupted by gain-of-function mutant cellular AP-1 proteins that preferentially bind methylated DNA
Mutation
38 21550622 Investigation of the function of the putative self-association site of Epstein-Barr virus (EBV) glycoprotein 42 (gp42)
Mutation
39 32176739 STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency
Mutation
40 28077791 Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency
Mutation
41 27009860 ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation
Mutation
42 21857817 C-terminal region of EBNA-2 determines the superior transforming ability of type 1 Epstein-Barr virus by enhanced gene regulation of LMP-1 and CXCR7
Mutation
43 31283782 Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity
Mutation
44 26751214 EBNA3C Directs Recruitment of RBPJ (CBF1) to Chromatin during the Process of Gene Repression in EBV Infected B Cells
Mutation
45 21440926 Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth
Mutation
46 26336822 Dissecting the contribution of EBNA3C domains important for EBV-induced B-cell growth and proliferation
Mutation
47 9733827 Role of the TRAF binding site and NF-kappaB activation in Epstein-Barr virus latent membrane protein 1-induced cell gene expression
Mutation
48 29134204 Latent Membrane Protein 1 Is a Novel Determinant of Epstein-Barr Virus Genome Persistence and Reactivation
Mutation
49 24886620 Difference in cytokine production and cell cycle progression induced by Epstein-Barr virus Lmp1 deletion variants in Kmh2, a Hodgkin lymphoma cell line
Mutation
50 32038504 Epstein-Barr Virus Latent Membrane Protein 1 Regulates Host B Cell MicroRNA-155 and Its Target FOXO3a via PI3K p110alpha Activation
Mutation
51 18986987 Tumor-derived variants of Epstein-Barr virus latent membrane protein 1 induce sustained Erk activation and c-Fos
Mutation
52 24682154 Genome-wide analysis of wild-type Epstein-Barr virus genomes derived from healthy individuals of the 1,000 Genomes Project
Mutation
53 21209116 Roscovitine inhibits EBNA1 serine 393 phosphorylation, nuclear localization, transcription, and episome maintenance
Mutation
54 35740565 Epstein-Barr Virus (EBV) Is Mostly Latent and Clonal in Angioimmunoblastic T Cell Lymphoma (AITL)
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.