Overview of HTLV1 associated Cell line (Mutation)

ID Literature Title Group
1 8011162 A spontaneous point mutation in the human T-cell leukemia virus type 1 pX gene leads to expression of a novel doubly spliced pX-mRNA that encodes a 25-kD, amino-terminal deleted rex protein
Mutation
2 25340740 HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation
Mutation
3 9710589 An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300
Mutation
4 11080799 Kinase-inducible domain-like region of HTLV type 1 tax is important for NF-kappaB activation
Mutation
5 8970957 Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat
Mutation
6 10567539 PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner
Mutation
7 10698501 Functional impairment of p73 and p51, the p53-related proteins, by the human T-cell leukemia virus type 1 Tax oncoprotein
Mutation
8 10734308 HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration
Mutation
9 10766811 p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex
Mutation
10 19356250 Induction of p21(CIP1/WAF1) expression by human T-lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilization
Mutation
11 10516045 Amino acid changes at positions 173 and 187 in the human T-cell leukemia virus type 1 surface glycoprotein induce specific neutralizing antibodies
Mutation
12 18480461 Intersubunit disulfide isomerization controls membrane fusion of human T-cell leukemia virus Env
Mutation
13 34343702 The N93D mutation of the human T-cell leukemia virus type 1 envelope glycoprotein found in symptomatic patients enhances neuropilin-1 b1 domain binding
Mutation
14 34298060 Structural Insights into the Mechanism of Human T-cell Leukemia Virus Type 1 Gag Targeting to the Plasma Membrane for Assembly
Mutation
15 9971764 Multiple functions for the basic amino acids of the human T-cell leukemia virus type 1 matrix protein in viral transmission
Mutation
16 29695435 Critical Role of the Human T-Cell Leukemia Virus Type 1 Capsid N-Terminal Domain for Gag-Gag Interactions and Virus Particle Assembly
Mutation
17 17577584 An N-terminal glycine-rich sequence contributes to retrovirus trimer of hairpins stability
Mutation
18 24284316 Palmitoylation and p8-mediated human T-cell leukemia virus type 1 transmission
Mutation
19 33562087 Biochemical Characterization, Specificity and Inhibition Studies of HTLV-1, HTLV-2, and HTLV-3 Proteases
Mutation
20 11000222 In vivo analysis of human T-cell leukemia virus type 1 reverse transcription accuracy
Mutation
21 19919707 Phosphorylation regulates human T-cell leukemia virus type 1 Rex function
Mutation
22 23785214 Human T lymphotropic virus type 1 SU residue 195 plays a role in determining the preferential CD4+ T cell immortalization/transformation tropism
Mutation
23 8756622 Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA
Mutation
24 10343169 Analysis of potential phosphorylation sites in human T cell leukemia virus type 1 Tax
Mutation
25 11070166 Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling
Mutation
26 14645559 The central region of human T-cell leukemia virus type 1 Tax protein contains distinct domains involved in subunit dimerization
Mutation
27 11046153 Distinct p300-responsive mechanisms promote caspase-dependent apoptosis by human T-cell lymphotropic virus type 1 Tax protein
Mutation
28 17535428 HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex
Mutation
29 21552325 NF-kappaB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ
Mutation
30 31299491 The human T-cell leukemia virus type-1 tax oncoprotein dissociates NF-kappaB p65(RelA)-Stathmin complexes and causes catastrophic mitotic spindle damage and genomic instability
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.