Overview of SARS-CoV-2 associated Cell line (Mutation)

ID Literature Title Group
1 34403732 Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry
Mutation
2 34433426 Investigation of Interaction between the Spike Protein of SARS-CoV-2 and ACE2-Expressing Cells Using an In Vitro Cell Capturing System
Mutation
3 34445669 Molecular Masks for ACE2 to Effectively and Safely Block SARS-CoV-2 Virus Entry
Mutation
4 34467913 An innovative approach for the non-invasive surveillance of communities and early detection of SARS-CoV-2 via solid waste analysis
Mutation
5 36149962 Role for N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity
Mutation
6 36153659 Pathogen-host adhesion between SARS-CoV-2 spike proteins from different variants and human ACE2 studied at single-molecule and single-cell levels
Mutation
7 36204651 Comparison of Intracellular Transcriptional Response of NHBE Cells to Infection with SARS-CoV-2 Washington and New York Strains
Mutation
8 36563151 The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation
Mutation
9 36590900 Network analysis uncovers the communication structure of SARS-CoV-2 spike protein identifying sites for immunogen design
Mutation
10 37809871 SARS-CoV-2 spike protein-derived immunogenic peptides that are promiscuously presented by several HLA-class II molecules and their potential for inducing acquired immunity
Mutation
11 37929963 SARS-CoV-2 NSP12 associates with TRiC and the P323L substitution acts as a host adaption
Mutation
12 37963924 Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes
Mutation
13 33968806 SARS CoV-2 Nucleoprotein Enhances the Infectivity of Lentiviral Spike Particles
Mutation
14 40253323 Tradeoffs between proliferation and transmission in virus evolution- insights from evolutionary and functional analyses of SARS-CoV-2
Mutation
15 39657661 Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity
Mutation
16 38548763 The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86
Mutation
17 37382441 Adaptive variations in SARS-CoV-2 spike proteins: effects on distinct virus-cell entry stages
Mutation
18 34226895 A bivalent recombinant vaccine targeting the S1 protein induces neutralizing antibodies against both SARS-CoV-2 variants and wild-type of the virus
Mutation
19 34214467 Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
Mutation
20 34228597 Human immunoglobulin from transchromosomic bovines hyperimmunized with SARS-CoV-2 spike antigen efficiently neutralizes viral variants
Mutation
21 34985974 Nanobody-Functionalized Cellulose for Capturing SARS-CoV-2
Mutation
22 32756549 SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness
Mutation
23 34464596 A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants
Mutation
24 33353101 SARS-CoV-2 Spike Alterations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus
Mutation
25 33524990 BNT162b vaccines protect rhesus macaques from SARS-CoV-2
Mutation
26 34367128 CAR-NK Cells Effectively Target SARS-CoV-2-Spike-Expressing Cell Lines In Vitro
Mutation
27 34417590 mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates
Mutation
28 34465913 Mechanical activation of spike fosters SARS-CoV-2 viral infection
Mutation
29 38005972 Gag Virus-like Particles Functionalized with SARS-CoV-2 Variants: Generation, Characterization and Recognition by COVID-19 Convalescent Patients' Sera
Mutation
30 38257736 Susceptibility and Resistance of SARS-CoV-2 Variants to LCB1 and Its Multivalent Derivatives
Mutation
31 38399999 Stabilization of the Metastable Pre-Fusion Conformation of the SARS-CoV-2 Spike Glycoprotein through N-Linked Glycosylation of the S2 Subunit
Mutation
32 38424106 Altered receptor binding, antibody evasion and retention of T cell recognition by the SARS-CoV-2 XBB.1.5 spike protein
Mutation
33 39048693 An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals
Mutation
34 38557175 Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike
Mutation
35 36852863 Systematic Exploration of SARS-CoV-2 Adaptation to Vero E6, Vero E6/TMPRSS2, and Calu-3 Cells
Mutation
36 36539656 Isolation and characterization of a SARS-CoV-2 variant with a Q677H mutation in the spike protein
Mutation
37 36084746 Identification of hACE2-interacting sites in SARS-CoV-2 spike receptor binding domain for antiviral drugs screening
Mutation
38 40062404 The Compensatory Effect of S375F on S371F Is Vital for Maintaining the Infectivity of SARS-CoV-2 Omicron Variants
Mutation
39 39772238 Development and Evaluation of a Newcastle Disease Virus-like Particle Vaccine Expressing SARS-CoV-2 Spike Protein with Protease-Resistant and Stability-Enhanced Modifications
Mutation
40 39379400 Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogens
Mutation
41 39805865 mRNA vaccines with RBD mutations have broad-spectrum activity against SARS-CoV-2 variants in mice
Mutation
42 37300832 Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail
Mutation
43 34537241 Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection
Mutation
44 37804113 Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus
Mutation
45 33567448 mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
Mutation
46 34430803 Epitope diversity of SARS-CoV-2 hyperimmune intravenous human immunoglobulins and neutralization of variants of concern
Mutation
47 39675720 The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery
Mutation
48 33097660 SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
Mutation
49 39905220 SARS-CoV-2 ORF3a accessory protein is a water-permeable channel that induces lysosome swelling
Mutation
50 33205709 Loss of orf3b in the circulating SARS-CoV-2 strains
Mutation
51 39841800 The R203M and D377Y mutations of the nucleocapsid protein promote SARS-CoV-2 infectivity by impairing RIG-I-mediated antiviral signaling
Mutation
52 39827186 Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera
Mutation
53 39470577 Structural insight into broadening SARS-CoV-2 neutralization by an antibody cocktail harbouring both NTD and RBD potent antibodies
Mutation
54 40062859 Potent antiviral activity of simnotrelvir against key epidemic SARS-CoV-2 variants with a high resistance barrier
Mutation
55 33907518 SARS-CoV-2 main protease suppresses type I interferon production by preventing nuclear translocation of phosphorylated IRF3
Mutation
56 37487098 Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence
Mutation
57 40132472 A live attenuated SARS-CoV-2 vaccine constructed by dual inactivation of NSP16 and ORF3a
Mutation
58 39932973 A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses
Mutation
59 39047088 In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance
Mutation
60 35317858 SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1
Mutation
61 36357440 Intranasal delivery of a rationally attenuated SARS-CoV-2 is immunogenic and protective in Syrian hamsters
Mutation
62 37842619 SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8(+) T cell responses
Mutation
63 33837182 GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein
Mutation
64 39567830 Viral N protein hijacks deaminase-containing RNA granules to enhance SARS-CoV-2 mutagenesis
Mutation
65 36059866 A DNA-based non-infectious replicon system to study SARS-CoV-2 RNA synthesis
Mutation
66 39571001 SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation
Mutation
67 35380892 Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2
Mutation
68 39259728 A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system
Mutation
69 39424074 Replication capacity and susceptibility of nirmatrelvir-resistant mutants to next-generation Mpro inhibitors in a SARS-CoV-2 replicon system
Mutation
70 37957287 Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors
Mutation
71 39319611 Miniaturized Modular Click Chemistry-enabled Rapid Discovery of Unique SARS-CoV-2 M(pro) Inhibitors With Robust Potency and Drug-like Profile
Mutation
72 37390404 Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease
Mutation
73 39616206 TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication
Mutation
74 37637734 Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir
Mutation
75 36689809 Ensitrelvir is effective against SARS-CoV-2 3CL protease mutants circulating globally
Mutation
76 33991487 Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant
Mutation
77 39983708 Respiratory Shedding of Infectious SARS-CoV-2 Omicron XBB.1.41.1 Lineage among Captive White-Tailed Deer, Texas, USA
Mutation
78 40135879 Role of glycosylation mutations at the N-terminal domain of SARS-CoV-2 XEC variant in immune evasion, cell-cell fusion, and spike stability
Mutation
79 33159417 Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection
Mutation
80 35403837 Potent Anti-SARS-CoV-2 Efficacy of COVID-19 Hyperimmune Globulin from Vaccine-Immunized Plasma
Mutation
81 39494911 A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation
Mutation
82 39684303 Features of Highly Homologous T-Cell Receptor Repertoire in the Immune Response to Mutations in Immunogenic Epitopes
Mutation
83 33558635 Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody
Mutation
84 36029764 Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites
Mutation
85 36351451 Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir
Mutation
86 35862965 Human ACE2 Genetic Polymorphism Affecting SARS-CoV and SARS-CoV-2 Entry into Cells
Mutation
87 35585971 Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection
Mutation
88 35164548 Genome-Wide Characterization of SARS-CoV-2 Cytopathogenic Proteins in the Search of Antiviral Targets
Mutation
89 35632693 SARS-CoV-2 Virion Infectivity and Cytokine Production in Primary Human Airway Epithelial Cells
Mutation
90 35062211 SARS-CoV-2 Spike Expression at the Surface of Infected Primary Human Airway Epithelial Cells
Mutation
91 35166573 Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection
Mutation
92 35215988 Influenza A(H1N1)pdm09 Virus but Not Respiratory Syncytial Virus Interferes with SARS-CoV-2 Replication during Sequential Infections in Human Nasal Epithelial Cells
Mutation
93 33336251 Multisystem Inflammatory Syndrome in Children in February 2020 and Implications of Genomic Sequencing for SARS-CoV-2
Mutation
94 37796123 Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics
Mutation
95 38168680 Adaptation of SARS-CoV-2 to ACE2(H353K) mice reveals new spike residues that drive mouse infection
Mutation
96 34746689 Functional differences among the spike glycoproteins of multiple emerging severe acute respiratory syndrome coronavirus 2 variants of concern
Mutation
97 38124756 Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant
Mutation
98 38421180 The SARS-CoV-2 Spike is a virulence determinant and plays a major role on the attenuated phenotype of Omicron virus in a feline model of infection
Mutation
99 38172120 TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Mutation
100 36062074 The neutralization of B.1.617.1 and B.1.1.529 sera from convalescent patients and BBIBP-CorV vaccines
Mutation
101 38332154 Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant
Mutation
102 38365933 SARS-CoV-2 rapidly evolves lineage-specific phenotypic differences when passaged repeatedly in immune-naive mice
Mutation
103 37651466 A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo
Mutation
104 37738983 Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
Mutation
105 38415690 Vero cell-adapted SARS-CoV-2 strain shows increased viral growth through furin-mediated efficient spike cleavage
Mutation
106 35849637 In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding
Mutation
107 36851122 Humoral Responses against BQ.1.1 Elicited after Breakthrough Infection and SARS-CoV-2 mRNA Vaccination
Mutation
108 34856891 A second functional furin site in the SARS-CoV-2 spike protein
Mutation
109 34855904 Niclosamide shows strong antiviral activity in a human airway model of SARS-CoV-2 infection and a conserved potency against the Alpha (B.1.1.7), Beta (B.1.351) and Delta variant (B.1.617.2)
Mutation
110 34859134 Production, Titration, Neutralisation, Storage and Lyophilisation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lentiviral Pseudotypes
Mutation
111 34843105 SARS-CoV-2 Neutralization in Convalescent Plasma and Commercial Lots of Plasma-Derived Immunoglobulin
Mutation
112 35609088 Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron
Mutation
113 34435953 Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics
Mutation
114 34603303 A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine
Mutation
115 34311587 B.1.526 SARS-CoV-2 Variants Identified in New York City are Neutralized by Vaccine-Elicited and Therapeutic Monoclonal Antibodies
Mutation
116 34060334 Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes
Mutation
117 33917138 The Impact on Infectivity and Neutralization Efficiency of SARS-CoV-2 Lineage B.1.351 Pseudovirus
Mutation
118 34414884 N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2
Mutation
119 34578354 SARS-CoV-2 Delta Variant Pathogenesis and Host Response in Syrian Hamsters
Mutation
120 33579792 The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2
Mutation
121 33860605 Polysulfates Block SARS-CoV-2 Uptake through Electrostatic Interactions*
Mutation
122 34311586 D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Virus Titer via Enhanced Furin-Mediated Spike Cleavage
Mutation
123 34406867 Natural and Recombinant SARS-CoV-2 Isolates Rapidly Evolve In Vitro to Higher Infectivity through More Efficient Binding to Heparan Sulfate and Reduced S1/S2 Cleavage
Mutation
124 34541573 Potent neutralizing RBD-specific antibody cocktail against SARS-CoV-2 and its mutant
Mutation
125 34307830 In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1
Mutation
126 38112266 The impact of S2 mutations on Omicron SARS-CoV-2 cell surface expression and fusogenicity
Mutation
127 38194968 Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants
Mutation
128 37452031 Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants
Mutation
129 37777967 Continued evasion of neutralizing antibody response by Omicron XBB.1.16
Mutation
130 38224840 Divergent pathogenetic outcomes in BALB/c mice following Omicron subvariant infection
Mutation
131 37789046 Effects of tea, catechins and catechin derivatives on Omicron subvariants of SARS-CoV-2
Mutation
132 35114110 Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display
Mutation
133 37196033 Spike substitution T813S increases Sarbecovirus fusogenicity by enhancing the usage of TMPRSS2
Mutation
134 36992294 Deep Mutational Scanning to Predict Escape from Bebtelovimab in SARS-CoV-2 Omicron Subvariants
Mutation
135 37219999 Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination
Mutation
136 36940324 Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor
Mutation
137 37243215 SARS-CoV-2 Omicron Specific Mutations Affecting Infectivity, Fusogenicity, and Partial TMPRSS2-Independency
Mutation
138 37192725 SARS-CoV-2 omicron sub-lineages differentially modulate interferon response in human lung epithelial cells
Mutation
139 37175863 Analysis of SARS-CoV-2 Spike Protein Variants with Recombinant Reporter Viruses Created from a Bacmid System
Mutation
140 37236995 Phase I randomized, observer-blinded, placebo-controlled study of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B
Mutation
141 37653342 Original SARS-CoV-2 monovalent and Omicron BA.4/BA.5 bivalent COVID-19 mRNA vaccines: phase 2/3 trial interim results
Mutation
142 37341536 A Noncoding A-to-U Kozak Site Change Related to the High Transmissibility of Alpha, Delta, and Omicron VOCs
Mutation
143 37502147 S373P Mutation Stabilizes the Receptor-Binding Domain of the Spike Protein in Omicron and Promotes Binding
Mutation
144 36288106 Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants
Mutation
145 39531918 A substitution at the cytoplasmic tail of the spike protein enhances SARS-CoV-2 infectivity and immunogenicity
Mutation
146 39408868 Insights into the Replication Kinetics Profiles of Malaysian SARS-CoV-2 Variant Alpha, Beta, Delta, and Omicron in Vero E6 Cell Line
Mutation
147 38026181 Impact of mutations defining SARS-CoV-2 Omicron subvariants BA.2.12.1 and BA.4/5 on Spike function and neutralization
Mutation
148 37943512 Evolution of SARS-CoV-2 Spikes shapes their binding affinities to animal ACE2 orthologs
Mutation
149 38320601 Predicting potential SARS-CoV-2 mutations of concern via full quantum mechanical modelling
Mutation
150 36155070 Repurposing of HIV/HCV protease inhibitors against SARS-CoV-2 3CL(pro)
Mutation
151 39609459 Machine learning-enhanced immunopeptidomics applied to T-cell epitope discovery for COVID-19 vaccines
Mutation
152 40157604 The SARS-CoV-2 NSP4 T492I mutation promotes double-membrane vesicle formation to facilitate transmission
Mutation
153 37947496 Discovery of Nirmatrelvir Resistance Mutations in SARS-CoV-2 3CLpro: A Computational-Experimental Approach
Mutation
154 35405385 Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern
Mutation
155 40298448 Comparative analysis of replication and immune evasion among SARS-CoV-2 subvariants BA.2.86, JN.1, KP.2, and KP.3
Mutation
156 39379369 Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3
Mutation
157 38048640 The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant
Mutation
158 39830514 S6P mutation in Delta and Omicron variant spike protein significantly enhances the efficacy of mRNA COVID-19 vaccines
Mutation
159 37676771 SARS-CoV-2 variants with NSP12 P323L/G671S mutations display enhanced virus replication in ferret upper airways and higher transmissibility
Mutation
160 38279353 Differential Ability of Spike Protein of SARS-CoV-2 Variants to Downregulate ACE2
Mutation
161 39631784 Differential Impact of Spike Protein Mutations on SARS-CoV-2 Infectivity and Immune Evasion: Insights from Delta and Kappa Variants
Mutation
162 38680520 A chimeric adenovirus-vectored vaccine based on Beta spike and Delta RBD confers a broad-spectrum neutralization against Omicron-included SARS-CoV-2 variants
Mutation
163 40299982 Variant mutation G215C in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation
Mutation
164 39684353 Exploring the Replication and Pathogenic Characteristics of Alpha, Delta, and Omicron Variants of SARS-CoV-2
Mutation
165 40358207 The NSP6-L260F substitution in SARS-CoV-2 BQ.1.1 and XBB.1.16 lineages compensates for the reduced viral polymerase activity caused by mutations in NSP13 and NSP14
Mutation
166 38675799 Engineered Multivalent Nanobodies Efficiently Neutralize SARS-CoV-2 Omicron Subvariants BA.1, BA.4/5, XBB.1 and BQ.1.1
Mutation
167 37731621 N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody
Mutation
168 37915256 Distinctive Combinations of RBD Mutations Contribute to Antibody Evasion in the Case of the SARS-CoV-2 Beta Variant
Mutation
169 34688376 Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner
Mutation
170 40248367 Heparan sulfate proteoglycans remodel SARS-CoV-2 spike conformation to allow integrin interaction and infection of endothelial cells
Mutation
171 38377136 Effectiveness of a broad-spectrum bivalent mRNA vaccine against SARS-CoV-2 variants in preclinical studies
Mutation
172 37479708 Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants
Mutation
173 38812550 Rapid spread of the SARS-CoV-2 JN.1 lineage is associated with increased neutralization evasion
Mutation
174 38793644 COVID-19 Serum Drives Spike-Mediated SARS-CoV-2 Variation
Mutation
175 38057313 Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant
Mutation
176 36240764 Evasion of neutralizing antibody responses by the SARS-CoV-2 BA.2.75 variant
Mutation
177 36039901 Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2
Mutation
178 39753670 Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic
Mutation
179 39660912 Combined mutations in nonstructural protein 14, envelope, and membrane proteins mitigate the neuropathogenicity of SARS-CoV-2 Omicron BA.1 in K18-hACE2 mice
Mutation
180 34225487 Replicative Fitness of a SARS-CoV-2 20I/501Y.V1 Variant from Lineage B.1.1.7 in Human Reconstituted Bronchial Epithelium
Mutation
181 38088562 High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1
Mutation
182 37402789 In vitro and in vivo characterization of SARS-CoV-2 strains resistant to nirmatrelvir
Mutation
183 34192518 Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease
Mutation
184 36870749 An ultrastructural and genomic study on the SARS-CoV-2 variant B.1.210 circulating during the first wave of COVID-19 pandemic in India
Mutation
185 37090707 Different configurations of SARS-CoV-2 spike protein delivered by integrase-defective lentiviral vectors induce persistent functional immune responses, characterized by distinct immunogenicity profiles
Mutation
186 34726473 A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice
Mutation
187 34688034 Evidence for retained spike-binding and neutralizing activity against emerging SARS-CoV-2 variants in serum of COVID-19 mRNA vaccine recipients
Mutation
188 38400128 Immune Evasion of SARS-CoV-2 Omicron Subvariants XBB.1.5, XBB.1.16 and EG.5.1 in a Cohort of Older Adults after ChAdOx1-S Vaccination and BA.4/5 Bivalent Booster
Mutation
189 36121299 The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 Variants
Mutation
190 38568894 Infection kinetics, syncytia formation, and inflammatory biomarkers as predictive indicators for the pathogenicity of SARS-CoV-2 Variants of Concern in Calu-3 cells
Mutation
191 36350154 The P681H Mutation in the Spike Glycoprotein of the Alpha Variant of SARS-CoV-2 Escapes IFITM Restriction and Is Necessary for Type I Interferon Resistance
Mutation
192 39412257 SARS-CoV-2 N protein coordinates viral particle assembly through multiple domains
Mutation
193 32730807 The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity
Mutation
194 38651897 The TRAF3-DYRK1A-RAD54L2 complex maintains ACE2 expression to promote SARS-CoV-2 infection
Mutation
195 40353671 Determinants of susceptibility to SARS-CoV-2 infection in murine ACE2
Mutation
196 39791910 Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D
Mutation
197 34488225 SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion
Mutation
198 39535372 Inactivation of Pseudovirus Expressing the D614G Spike Protein Mutation using Nitric Oxide-Plasma Activated Water
Mutation
199 34061377 Inhibitory effect on SARS-CoV-2 infection of neferine by blocking Ca(2+) -dependent membrane fusion
Mutation
200 37037866 High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike
Mutation
201 37041132 High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2
Mutation
202 37132357 Impaired potency of neutralizing antibodies against cell-cell fusion mediated by SARS-CoV-2
Mutation
203 37331111 An in vitro workflow to create and modify infectious clones using replication cycle reaction
Mutation
204 37338298 A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance
Mutation
205 32991842 Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant
Mutation
206 33243994 SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
Mutation
207 33326798 An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2
Mutation
208 33436577 A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein
Mutation
209 33521163 Comprehensive and systemic optimization for improving the yield of SARS-CoV-2 spike pseudotyped virus
Mutation
210 34204754 Previous SARS-CoV-2 Infection Increases B.1.1.7 Cross-Neutralization by Vaccinated Individuals
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.