Overview of CHIKV associated Chikungunya Fever (Mutation)

ID Literature Title Group
1 20417142 An outbreak of chikungunya in southern Thailand from 2008 to 2009 caused by African strains with A226V mutation
Mutation
2 30126424 Differences in genome characters and cell tropisms between two chikungunya isolates of Asian lineage and Indian Ocean lineage
Mutation
3 31292455 Genomic epidemiology of Chikungunya virus in Colombia reveals genetic variability of strains and multiple geographic introductions in outbreak, 2014
Mutation
4 27423270 Two novel epistatic mutations (E1:K211E and E2:V264A) in structural proteins of Chikungunya virus enhance fitness in Aedes aegypti
Mutation
5 27430542 Genetic Characterization of Northwestern Colombian Chikungunya Virus Strains from the 2014-2015 Epidemic
Mutation
6 35062275 Genetic Diversity and Spatiotemporal Dynamics of Chikungunya Infections in Mexico during the Outbreak of 2014-2016
Mutation
7 35385544 Molecular and biological characterization of an Asian-American isolate of Chikungunya virus
Mutation
8 26781948 Identification of Asian genotype of chikungunya virus isolated in Mexico
Mutation
9 30860010 Global Outbreaks and Origins of a Chikungunya Virus Variant Carrying Mutations Which May Increase Fitness for Aedes aegypti: Revelations from the 2016 Mandera, Kenya Outbreak
Mutation
10 28480053 Understanding the evolution and spread of chikungunya virus in the Americas using complete genome sequences
Mutation
11 19683467 Chikungunya virus of Asian and Central/East African genotypes in Malaysia
Mutation
12 26201250 Independent Emergence of the Cosmopolitan Asian Chikungunya Virus, Philippines 2012
Mutation
13 24951535 Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral
Mutation
14 19851853 Genetic characterization of 2006-2008 isolates of Chikungunya virus from Kerala, South India, by whole genome sequence analysis
Mutation
15 24465661 A novel 2006 Indian outbreak strain of Chikungunya virus exhibits different pattern of infection as compared to prototype strain
Mutation
16 29348674 Variation at position 350 in the Chikungunya virus 6K-E1 protein determines the sensitivity of detection in a rapid E1-antigen test
Mutation
17 23725047 Chikungunya virus with E1-A226V mutation causing two outbreaks in 2010, Guangdong, China
Mutation
18 33690657 Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019
Mutation
19 34592442 Chikungunya viruses containing the A226V mutation detected retrospectively in Cameroon form a new geographical subclade
Mutation
20 37029884 The First Genomic Characterization of the Chikungunya Virus in Saudi Arabia
Mutation
21 18632966 A226V mutation in virus during the 2007 chikungunya outbreak in Kerala, India
Mutation
22 19955565 Re-emergence of Chikungunya virus in South-east Asia: virological evidence from Sri Lanka and Singapore
Mutation
23 20704755 Molecular characterization of Chikungunya virus isolates from clinical samples and adult Aedes albopictus mosquitoes emerged from larvae from Kerala, South India
Mutation
24 21395419 Entomological investigation and control of a chikungunya cluster in Singapore
Mutation
25 22299053 Chikungunya virus infection of cell lines: analysis of the East, Central and South African lineage
Mutation
26 22363413 Chikungunya infection in India: results of a prospective hospital based multi-centric study
Mutation
27 22484761 Molecular investigations of chikungunya virus during outbreaks in Orissa, Eastern India in 2010
Mutation
28 22925018 Detection of Chikungunya virus in wild populations of Aedes albopictus in Kerala State, India
Mutation
29 23965757 Outbreak of chikungunya virus infection, Vanimo, Papua New Guinea
Mutation
30 24126361 Differential regulation of TLR mediated innate immune response of mouse neuronal cells following infection with novel ECSA genotype of Chikungunya virus with and without E1:A226V mutation
Mutation
31 24166737 Chikungunya emergency in China: microevolution and genetic analysis for a local outbreak
Mutation
32 24829346 Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes
Mutation
33 25113745 Chikungunya virus was isolated in Thailand, 2010
Mutation
34 26752630 Long-Lasting Immune Protection and Other Epidemiological Findings after Chikungunya Emergence in a Cambodian Rural Community, April 2012
Mutation
35 26943997 Identification and genetic characterization of chikungunya virus from Aedes mosquito vector collected in the Lucknow district, North India
Mutation
36 27571254 Antigenic Variation of East/Central/South African and Asian Chikungunya Virus Genotypes in Neutralization by Immune Sera
Mutation
37 29076806 Molecular Characterization of Autochthonous Chikungunya Cluster in Latium Region, Italy
Mutation
38 30073419 Genetic characterization of chikungunya viruses isolated during the 2015-2017 outbreaks in different states of India, based on their E1 and E2 genes
Mutation
39 30192396 Epidemiological trends and molecular dynamics of dengue, chikungunya virus infection, coinfection, and other undifferentiated fever during 2015-2016 in Odisha, India
Mutation
40 30424530 Following in the Footsteps of the Chikungunya Virus in Brazil: The First Autochthonous Cases in Amapa in 2014 and Its Emergence in Rio de Janeiro during 2016
Mutation
41 30666947 East/Central/South African Genotype in a Chikungunya Outbreak, Dhaka, Bangladesh, 2017
Mutation
42 30729309 Genome sequences of chikungunya virus isolates circulating in midwestern Brazil
Mutation
43 31247338 Molecular and phylogenetic analysis of Chikungunya virus in Central India during 2016 and 2017 outbreaks reveal high similarity with recent New Delhi and Bangladesh strains
Mutation
44 31382507 Genetic Characterization of Chikungunya Virus in Field-Caught Aedes aegypti Mosquitoes Collected during the Recent Outbreaks in 2019, Thailand
Mutation
45 31496530 Differential susceptibility & replication potential of Vero E6, BHK-21, RD, A-549, C6/36 cells & Aedes aegypti mosquitoes to three strains of chikungunya virus
Mutation
46 31834526 Genome sequences of chikungunya virus isolates from an outbreak in southwest Bangkok in 2018
Mutation
47 31900943 Continual circulation of ECSA genotype and identification of a novel mutation I317V in the E1 gene of Chikungunya viral strains in southern India during 2015-2016
Mutation
48 31976828 Long-Term Persistence of Chikungunya Virus-Associated Manifestations and Anti-Chikungunya Virus Antibody in Southern Thailand: 5 Years After an Outbreak in 2008-2009
Mutation
49 32787529 Molecular characterization of chikungunya virus during the 2019 outbreak in the Democratic Republic of the Congo
Mutation
50 32933109 Chikungunya Outbreak in the Republic of the Congo, 2019-Epidemiological, Virological and Entomological Findings of a South-North Multidisciplinary Taskforce Investigation
Mutation
51 33156857 Emergence of a novel chikungunya virus strain bearing the E1:V80A substitution, out of the Mombasa, Kenya 2017-2018 outbreak
Mutation
52 33213040 A Novel Sub-Lineage of Chikungunya Virus East/Central/South African Genotype Indian Ocean Lineage Caused Sequential Outbreaks in Bangladesh and Thailand
Mutation
53 33236121 Molecular characterization and phylogenetic analysis of Chikungunya virus during the 2016 outbreak in Sergipe, northeastern Brazil
Mutation
54 33755229 Epidemiology of Chikungunya virus isolates 2016-2018 in Pakistan
Mutation
55 34339381 Chikungunya Fever in Southern Thailand, 2018
Mutation
56 34623503 Genetic characterization of chikungunya virus isolates from Aedes aegypti mosquitoes collected during a recent outbreak in Bangkok, Thailand
Mutation
57 34935436 Emerging Chikungunya Virus Variants at the E1-E1 Interglycoprotein Spike Interface Impact Virus Attachment and Inflammation
Mutation
58 35032014 Genetic characterization of Chikungunya virus circulating in individuals from Parana, Brazil
Mutation
59 35348916 Molecular characterization of chikungunya virus from the first cluster of patients during the 2020 outbreak in Chad
Mutation
60 35475905 Molecular aspects of Chikungunya virus infections in cancer patients
Mutation
61 36016427 Virological, Serological and Clinical Analysis of Chikungunya Virus Infection in Thai Patients
Mutation
62 36298867 Genomic Epidemiology Reveals the Circulation of the Chikungunya Virus East/Central/South African Lineage in Tocantins State, North Brazil
Mutation
63 36441828 Chikungunya virus (CHIKV) seroprevalence in the South Pacific populations of the Cook Islands and Vanuatu with associated environmental and social factors
Mutation
64 36774411 The evolution of chikungunya virus circulating in Indonesia: Sequence analysis of the orf2 gene encoding the viral structural proteins
Mutation
65 37030472 Coinfection and circulation of chikungunya virus and dengue virus in pediatric patients in Myanmar, 2019
Mutation
66 37184895 Genomic Characterization of Mosquito Isolates of Chikungunya Virus (Outbreak Strains 2022) Using Next-Generation Sequencing
Mutation
67 38009608 Understanding the resurgence of chikungunya virus during 2020-2021 in Pune, India, based on genomic analyses: A seven year study
Mutation
68 38820892 Exploring the Chikungunya virus landscape in a dengue-endemic Brazilian area
Mutation
69 23684629 Genetic characterization of E2 region of Chikungunya virus circulating in Odisha, Eastern India from 2010 to 2011
Mutation
70 29185115 The synergistic effect of nsP2-L(618), nsP3-R(117), and E2-K(187) on the large plaque phenotype of chikungunya virus
Mutation
71 36126430 Regional mutations in CHIKV-ECSA genomes and detection of other viruses in the serum of acute febrile patients by a metagenomic approach in Mato Grosso, Central-Western Brazil, 2018
Mutation
72 26347221 Genetic divergence of Chikungunya virus plaque variants from the Comoros Island (2005)
Mutation
73 34941888 Chikungunya virus: Molecular epidemiology of nonstructural proteins in Pakistan
Mutation
74 30668592 Multiple roles of the non-structural protein 3 (nsP3) alphavirus unique domain (AUD) during Chikungunya virus genome replication and transcription
Mutation
75 40006946 The Chikungunya Virus nsP3 Macro Domain Inhibits Activation of the NF-kappaB Pathway
Mutation
76 28286701 First Report of the East-Central South African Genotype of Chikungunya Virus in Rio de Janeiro, Brazil
Mutation
77 40143357 Phylogenetic Analysis of Chikungunya Virus Eastern/Central/South African-Indian Ocean Epidemic Strains, 2004-2019
Mutation
78 30856200 An epidemic of chikungunya in northwestern Bangladesh in 2011
Mutation
79 34635129 Source-tracking of the Chinese Chikungunya viruses suggests that Indian subcontinent and Southeast Asia act as major hubs for the recent global spread of Chikungunya virus
Mutation
80 39058744 The evolutionary and molecular history of a chikungunya virus outbreak lineage
Mutation
81 37468826 Importation of a novel Indian Ocean lineage carrying E1-K211E and E2-V264A of Chikungunya Virus in Zhejiang Province, China, in 2019
Mutation
82 27108077 Vertical transmission of Indian Ocean Lineage of chikungunya virus in Aedes aegypti and Aedes albopictus mosquitoes
Mutation
83 29871722 Vector competence of Aedes albopictus for the Indian Ocean lineage (IOL) chikungunya viruses of the 2007 and 2017 outbreaks in Italy: a comparison between strains with and without the E1:A226V mutation
Mutation
84 35208808 Spread of a Novel Indian Ocean Lineage Carrying E1-K211E/E2-V264A of Chikungunya Virus East/Central/South African Genotype across the Indian Subcontinent, Southeast Asia, and Eastern Africa
Mutation
85 29785069 Genetic characterization of Chikungunya virus 2009 isolates from South India
Mutation
86 39715491 Emerging West African Genotype Chikungunya Virus in Mosquito Virome
Mutation
87 18069894 A single mutation in chikungunya virus affects vector specificity and epidemic potential
Mutation
88 22386853 pH-dependent entry of chikungunya virus into Aedes albopictus cells
Mutation
89 31167461 RNASeq Analysis of Aedes albopictus Mosquito Midguts after Chikungunya Virus Infection
Mutation
90 20078896 Genetic analysis of chikungunya viruses imported to mainland China in 2008
Mutation
91 39448916 Emergence of ECSA-IOL E1-K211E/E2-V264A Lineage of Chikungunya virus during Malaysian 2021 outbreak
Mutation
92 40196062 Molecular Typing of Chikungunya Virus at a Regional Advanced Healthcare Facility in Central India: A Three-Year Prospective Study
Mutation
93 19066782 Clinical and virological characterization of imported cases of Chikungunya fever
Mutation
94 24905288 TLR3 mediated innate immune response in mice brain following infection with Chikungunya virus
Mutation
95 18940268 Evolutionary rates and timescale comparison of Chikungunya viruses inferred from the whole genome/E1 gene with special reference to the 2005-07 outbreak in the Indian subcontinent
Mutation
96 21344151 Chikungunya virus isolates with/without A226V mutation show different sensitivity to IFN-a, but similar replication kinetics in non human primate cells
Mutation
97 21465340 Chikungunya virus infection
Mutation
98 21801412 Chikungunya virus adaptation to Aedes albopictus mosquitoes does not correlate with acquisition of cholesterol dependence or decreased pH threshold for fusion reaction
Mutation
99 22244786 Origin, evolution, and phylogeography of recent epidemic CHIKV strains
Mutation
100 22246833 Genetic diversity of Chikungunya virus, India 2006-2010: evolutionary dynamics and serotype analyses
Mutation
101 22520648 Cell-based analysis of Chikungunya virus E1 protein in membrane fusion
Mutation
102 24294963 Serological correlates of immune protection conferred by Chikungunya virus infection
Mutation
103 24880071 Development and evaluation of baculovirus-expressed Chikungunya virus E1 envelope proteins for serodiagnosis of Chikungunya infection
Mutation
104 26611825 Correlation of phylogenetic clade diversification and in vitro infectivity differences among Cosmopolitan genotype strains of Chikungunya virus
Mutation
105 27383735 Importance of mosquito "quasispecies" in selecting an epidemic arthropod-borne virus
Mutation
106 30385797 Evolution of Chikungunya virus in mosquito cells
Mutation
107 30717086 Analysis of Salivary Glands and Saliva from Aedes albopictus and Aedes aegypti Infected with Chikungunya Viruses
Mutation
108 30924912 Novel Molecular Signatures of Chikungunya Virus in Puerto Rico
Mutation
109 31096054 Re-emergence of chikungunya in the Republic of the Congo in 2019 associated with a possible vector-host switch
Mutation
110 31483508 Chikungunya virus modulates the miRNA expression patterns in human synovial fibroblasts
Mutation
111 33567556 Dynamic Molecular Epidemiology Reveals Lineage-Associated Single-Nucleotide Variants That Alter RNA Structure in Chikungunya Virus
Mutation
112 34048233 Discovery of a Potent and Selective Chikungunya Virus Envelope Protein Inhibitor through Computer-Aided Drug Design
Mutation
113 35416719 Two Conserved Phenylalanine Residues in the E1 Fusion Loop of Alphaviruses Are Essential for Viral Infectivity
Mutation
114 38842335 Changes in the chikungunya virus E1 glycoprotein domain II and hinge influence E2 conformation, infectivity, and virus-receptor interactions
Mutation
115 39469502 Genetic characterization and phylogenetic analysis of Chikungunya Virus: A case from Jeddah during the COVID-19 Pandemic
Mutation
116 40053531 Chikungunya virus in Europe: A retrospective epidemiology study from 2007 to 2023
Mutation
117 21440006 In vitro antiviral activity of arbidol against Chikungunya virus and characteristics of a selected resistant mutant
Mutation
118 28747508 Mutations in the E2 Glycoprotein and the 3' Untranslated Region Enhance Chikungunya Virus Virulence in Mice
Mutation
119 31387277 Genetic Variability of Chikungunya Virus in Southern Mexico
Mutation
120 32191995 Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection
Mutation
121 33437257 Sub-genomic analysis of Chikungunya virus E2 mutations in Pakistani isolates potentially modulating B-cell & T-Cell immune response
Mutation
122 35196388 Chikungunya Virus Vaccine Candidate Incorporating Synergistic Mutations Is Attenuated and Protects Against Virulent Virus Challenge
Mutation
123 35215875 Chikungunya Virus' High Genomic Plasticity Enables Rapid Adaptation to Restrictive A549 Cells
Mutation
124 38229040 Attenuation of neurovirulence of chikungunya virus by a single amino acid mutation in viral E2 envelope protein
Mutation
125 38932154 A 44-Nucleotide Region in the Chikungunya Virus 3' UTR Dictates Viral Fitness in Disparate Host Cells
Mutation
126 30135220 Differential Transmission of Antiviral Drug-Resistant Chikungunya Viruses by Aedes Mosquitoes
Mutation
127 31015278 Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate
Mutation
128 31217251 Design and Use of Chikungunya Virus Replication Templates Utilizing Mammalian and Mosquito RNA Polymerase I-Mediated Transcription
Mutation
129 27845418 Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue
Mutation
130 31000599 Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase
Mutation
131 33903104 Radicicol Inhibits Chikungunya Virus Replication by Targeting Nonstructural Protein 2
Mutation
132 34112897 Facile method for delivering chikungunya viral replicons into mosquitoes and mammalian cells
Mutation
133 39804924 Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine
Mutation
134 38675976 U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing
Mutation
135 21896755 Arbovirus high fidelity variant loses fitness in mosquitoes and mice
Mutation
136 30429348 Chikungunya Virus Fidelity Variants Exhibit Differential Attenuation and Population Diversity in Cell Culture and Adult Mice
Mutation
137 28381577 Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase
Mutation
138 40007036 Attenuation of Chikungunya Virus by a Single Amino Acid Substitution in the nsP1 Component of a Non-Structural Polyprotein
Mutation
139 25814598 Complete genome sequence of a chikungunya virus imported from bali to Germany
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.