Overview of HBV associated Hepatitis B Virus Infection

ID Literature Title Group
1 35415256 Precore/core mutations of hepatitis B virus genotype D arising in different states of infection
Mutation
2 31189581 Characterization and Clinical Significance of Natural Variability in Hepatitis B Virus Reverse Transcriptase in Treatment-Naive Chinese Patients by Sanger Sequencing and Next-Generation Sequencing
Mutation
3 19817965 Occult hepatitis B virus infection and lamivudine-resistant mutations in isolates from renal patients undergoing hemodialysis
Mutation
4 26457811 Occult HBV Infection May Be Transmitted through Close Contact and Manifest as an Overt Infection
Mutation
5 19800842 Hepatitis B precore/core promoter mutations in isolates from HBV-monoinfected and HBV-HIV coinfected patients: a 3-yr prospective study
Mutation
6 26390290 Detection of Hepatitis B Virus (HBV) Genomes and HBV Drug Resistant Variants by Deep Sequencing Analysis of HBV Genomes in Immune Cell Subsets of HBV Mono-Infected and/or Human Immunodeficiency Virus Type-1 (HIV-1) and HBV Co-Infected Individuals
Mutation
7 27354181 HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia
Mutation
8 2304145 Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen
Mutation
9 9519838 Proline-138 is essential for the assembly of hepatitis B virus core protein
Mutation
10 9751010 Incidence and clinical significance of hepatitis B virus precore gene translation initiation mutations in e antigen-negative patients
Mutation
11 9828233 Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro
Mutation
12 9841851 Identification of hepatitis B surface antigen variants with alterations outside the "a" determinant in immunized Singapore infants
Mutation
13 9875378 The hepatitis B virus M539V polymerase variation responsible for 3TC resistance also confers cross-resistance to other nucleoside analogues
Mutation
14 10091998 Functional analysis of mutations conferring lamivudine resistance on hepatitis B virus
Mutation
15 10320044 Hepatitis B virus variants with lamivudine-related mutations in the DNA polymerase and the 'a' epitope of the surface antigen are sensitive to ganciclovir
Mutation
16 10353255 Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues
Mutation
17 10364324 The mechanism of an immature secretion phenotype of a highly frequent naturally occurring missense mutation at codon 97 of human hepatitis B virus core antigen
Mutation
18 10377169 Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors
Mutation
19 10385663 Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under HBIg immunoglobulin after liver transplantation
Mutation
20 10430358 Liver graft infection by HBV S-gene mutants in transplant patients receiving long-term HBIg prophylaxis
Mutation
21 10534721 Hepatitis B virus core promoter mutations in children with multiple anti-HBe/HBeAg reactivations result in enhanced promoter activity
Mutation
22 10559327 Subtype-independent immature secretion and subtype-dependent replication deficiency of a highly frequent, naturally occurring mutation of human hepatitis B virus core antigen
Mutation
23 10573159 Hepatitis B virus maturation is affected by the incorporation of core proteins having a C-terminal substitution of arginine or lysine stretches
Mutation
24 10596008 Effect of variation in the common "a" determinant on the antigenicity of hepatitis B surface antigen
Mutation
25 10613749 In vitro evaluation of hepatitis B virus polymerase mutations associated with famciclovir resistance
Mutation
26 10628774 Fulminant hepatic failure resulting from lamivudine-resistant hepatitis B virus in a renal transplant recipient: durable response after orthotopic liver transplantation on adefovir dipivoxil and hepatitis B immune globulin
Mutation
27 10669360 Selection of multiresistant hepatitis B virus during sequential nucleoside-analogue therapy
Mutation
28 10682123 Analysis of hepatitis B virus quasispecies changes during emergence and reversion of lamivudine resistance in liver transplantation
Mutation
29 10760047 Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir
Mutation
30 10775637 A frequent, naturally occurring mutation (P130T) of human hepatitis B virus core antigen is compensatory for immature secretion phenotype of another frequent variant (I97L)
Mutation
31 10827158 Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy
Mutation
32 10982356 Low-level secretion of human hepatitis B virus virions caused by two independent, naturally occurring mutations (P5T and L60V) in the capsid protein
Mutation
33 11120616 Intra-familial evidence of horizontal transmission of hepatitis B virus surface antigen mutant G145R
Mutation
34 11181644 The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance
Mutation
35 11208474 Analysis of HBs antigen negative variant of hepatitis B virus: unique substitutions, Glu129 to Asp and Gly145 to Ala in the surface antigen gene
Mutation
36 11230757 Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region
Mutation
37 11287420 Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway
Mutation
38 11312349 Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC)
Mutation
39 11395201 Anti-HBs after hepatitis B immunization with plasma-derived and recombinant DNA-derived vaccines: binding to mutant HBsAg
Mutation
40 11509998 Effectiveness of hepatitis B vaccination in babies born to hepatitis B surface antigen-positive mothers in Italy
Mutation
41 11526151 Phylogenetic origin of hepatitis B virus strains with precore C-1858 variant
Mutation
42 11596084 Residual hepatitis B virus particles in liver transplant recipients receiving lamivudine: PCR quantitation of HBV DNA and ELISA of preS1 antigen
Mutation
43 11696228 Characterization of a novel hepatitis B virus mutant: demonstration of mutation-induced hepatitis B virus surface antigen group specific "a" determinant conformation change and its application in diagnostic assays
Mutation
44 11780452 Hepatitis B virus S gene mutants in infants infected despite immunoprophylaxis
Mutation
45 11851835 Prevalence of vaccine-induced escape mutants of hepatitis B virus in the adult population in China: a prospective study in 176 restaurant employees
Mutation
46 11886250 Reduced antigenicity of the hepatitis B virus HBsAg protein arising as a consequence of sequence changes in the overlapping polymerase gene that are selected by lamivudine therapy
Mutation
47 12050364 Influence of a putative intermolecular interaction between core and the pre-S1 domain of the large envelope protein on hepatitis B virus secretion
Mutation
48 12089278 Sensitive detection of HBsAg mutants by a gap ligase chain reaction assay
Mutation
49 12121939 Novel nucleoside analogue MCC-478 (LY582563) is effective against wild-type or lamivudine-resistant hepatitis B virus
Mutation
50 12167344 Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the "fingers" subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene
Mutation
51 12171302 Identification of a new variant in the YMDD motif of the hepatitis B virus polymerase gene selected during lamivudine therapy
Mutation
52 12414948 Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus
Mutation
53 12448687 Hepatitis B virus resistance to lamivudine and its clinical implications
Mutation
54 12457969 Presence of hepatitis B surface antigen mutant G145R DNA in the peripheral blood leukocytes of the family members of an asymptomatic carrier and evidence of its horizontal transmission
Mutation
55 12526951 Genotypic and phenotypic resistance: longitudinal and sequential analysis of hepatitis B virus polymerase mutations in patients with lamivudine resistance after liver transplantation
Mutation
56 12667359 [The prevalence of hepatitis B virus precore mutant isolated from asymptomatic carriers in Guangxi]
Mutation
57 12747252 Development of peptide nucleic acid mediated polymerase chain reaction clamping (PMPC)--direct sequencing method for detecting lamivudine-resistant hepatitis B virus (HBV) variants with high sensitivity and specificity
Mutation
58 12757503 High frequency of hepatitis B virus infection in patients with beta-thalassemia receiving multiple transfusions
Mutation
59 12760870 Generation of stable cell lines expressing Lamivudine-resistant hepatitis B virus for antiviral-compound screening
Mutation
60 12780567 Characterization of hepatitis B virus surface antigen and polymerase mutations in liver transplant recipients pre- and post-transplant
Mutation
61 12823591 YSDD: a novel mutation in HBV DNA polymerase confers clinical resistance to lamivudine
Mutation
62 12870011 [Analysis of three lamivudine-resistant HBV mutants with the method of restriction enzyme digestion and its application]
Mutation
63 12885906 Endocytosis of hepatitis B immune globulin into hepatocytes inhibits the secretion of hepatitis B virus surface antigen and virions
Mutation
64 12918112 Novel assay of competitively differentiated polymerase chain reaction for screening point mutation of hepatitis B virus
Mutation
65 12966541 Evolution of hepatitis B virus sequence from a liver transplant recipient with rapid breakthrough despite hepatitis B immune globulin prophylaxis and lamivudine therapy
Mutation
66 14557667 The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro
Mutation
67 14578867 Deficiency in virion secretion and decreased stability of the hepatitis B virus immune escape mutant G145R
Mutation
68 14638401 Mutations of the surface protein of hepatitis B virus
Mutation
69 14642631 Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient
Mutation
70 14645551 Stability and morphology comparisons of self-assembled virus-like particles from wild-type and mutant human hepatitis B virus capsid proteins
Mutation
71 14688448 Classifying hepatitis B virus genotypes
Mutation
72 14742682 Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates
Mutation
73 14748061 Clade analysis and surface antigen polymorphism of hepatitis B virus American genotypes
Mutation
74 14968937 Mechanism of antiviral activities of 3'-substituted L-nucleosides against 3TC-resistant HBV polymerase: a molecular modelling approach
Mutation
75 14981758 Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping
Mutation
76 14987532 Detection of hepatitis B virus variants resistant to lamivudine and famciclovir among randomly selected chronic carriers from Spain
Mutation
77 15016847 Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene
Mutation
78 15158343 Real-time quantification of hepatitis B virus core-promoter and pre-core mutants during hepatitis E antigen seroconversion
Mutation
79 15239096 Usefulness of dried blood samples for quantification and molecular characterization of HBV-DNA
Mutation
80 15261293 Molecular mechanisms of adefovir sensitivity and resistance in HBV polymerase mutants: a molecular dynamics study
Mutation
81 15280461 Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of Lamivudine-resistant mutants
Mutation
82 15328117 Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine
Mutation
83 15361503 Survey of hepatitis B surface variant infection in children 15 years after a nationwide vaccination programme in Taiwan
Mutation
84 15469692 Increased DNA polymerase fidelity of the Lamivudine resistant variants of human hepatitis B virus DNA polymerase
Mutation
85 15472342 Pyrosequencing for detection of lamivudine-resistant hepatitis B virus
Mutation
86 15564475 Nucleolar localization of human hepatitis B virus capsid protein
Mutation
87 15872296 Prevalence, incidence, and clinical relevance of the reverse transcriptase V207I mutation outside the YMDD motif of the hepatitis B virus polymerase during lamivudine therapy
Mutation
88 15915463 Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir
Mutation
89 15918335 Evaluation of methods for monitoring drug resistance in chronic hepatitis B patients during lamivudine therapy based on mass spectrometry and reverse hybridization
Mutation
90 15962387 Optimization of competitively differentiated polymerase chain reaction in detection of HBV basal core promoter mutation
Mutation
91 15968333 Hepatitis B Virus e Antigen Variants
Mutation
92 15968338 Natural History and Clinical Consequences of Hepatitis B Virus Infection
Mutation
93 15980328 Emergence of a novel mutation in the FLLA region of hepatitis B virus during lamivudine therapy
Mutation
94 15993954 Validation and comparison of different PCR-based methods for detection of hepatitis B virus precore region mutants
Mutation
95 16094714 Biological impacts of "hot-spot" mutations of hepatitis B virus X proteins are genotype B and C differentiated
Mutation
96 16246191 Community-based epidemiology of hepatitis B virus infection in West Bengal, India: prevalence of hepatitis B e antigen-negative infection and associated viral variants
Mutation
97 16273841 [Characterisation of an HBsAg mutant of hepatitis B virus (HBV) isolated from a dialysed patient involved in an occupational accident]
Mutation
98 16299725 Frequency of hepatitis B virus 'a' determinant variants in unselected Spanish chronic carriers
Mutation
99 16372296 Characteristics of hepatitis B virus in Ghana: full length genome sequences indicate the endemicity of genotype E in West Africa
Mutation
100 16373428 Genotypic resistance to lamivudine among hepatitis B virus isolates in Mexico
Mutation
101 16378961 Point mutations upstream of hepatitis B virus core gene affect DNA replication at the step of core protein expression
Mutation
102 16378967 Dynamics of hepatitis B virus resistance to lamivudine
Mutation
103 16380661 [The incidence rate of hepatitis B virus surface gene variants in Korean children with immunoprophylaxis failure of perinatal infection]
Mutation
104 16419112 Fatal liver failure with the emergence of hepatitis B surface antigen variants with multiple stop mutations after discontinuation of lamivudine therapy
Mutation
105 16419114 Hepatitis B virus genotyping, core promoter, and precore/core mutations among Afghan patients infected with hepatitis B: a preliminary report
Mutation
106 16461214 Mechanism of HBV genome variability and replication of HBV mutants
Mutation
107 16461216 The current management of HBV drug resistance
Mutation
108 16517839 Phylogenetic, virological, and clinical characteristics of genotype C hepatitis B virus with TCC at codon 15 of the precore region
Mutation
109 16553556 HBsAg diagnostic kits in the detection of hepatitis B virus mutation within "a" determinant
Mutation
110 16571836 Hepatitis B virus particle formation in the absence of pregenomic RNA and reverse transcriptase
Mutation
111 16611347 Case report of lamivudine-resistant hepatitis B virus infection post liver transplantation from a hepatitis B core antibody donor
Mutation
112 16622880 Diagnostic impact of the genetic variability of the hepatitis B virus surface antigen gene
Mutation
113 16622882 Infections by hepatitis B surface antigen gene mutants in Europe and North America
Mutation
114 16673294 Antiviral drug resistance: clinical consequences and molecular aspects
Mutation
115 16789016 Detection of a hepatitis B surface antigen variant emerging in a patient with chronic lymphocytic leukaemia treated with fludarabine
Mutation
116 16801428 Intracellular metabolism and in vitro activity of tenofovir against hepatitis B virus
Mutation
117 16954295 Detection of hepatitis B virus (HBV) genotype E carried--even in the presence of high titers of anti-HBs antibodies--by an Argentinean patient of African descent who had received vaccination against HBV
Mutation
118 17020942 Analysis of the cytosolic domains of the hepatitis B virus envelope proteins for their function in viral particle assembly and infectivity
Mutation
119 17063521 A low rate of hepatitis B virus vaccine breakthrough infections in Mongolia
Mutation
120 17115304 Analysis of hepatitis B surface antigen mutations in Mongolia: molecular epidemiology and implications for mass vaccination
Mutation
121 17201657 Hepatitis B virus DNA in unusual serological profiles of hepatitis B surface antigen-positive sera
Mutation
122 17210268 A new hepatitis B virus vaccine escape mutation in a renal transplant recipient
Mutation
123 17215289 In vitro study of the effects of precore and lamivudine-resistant mutations on hepatitis B virus replication
Mutation
124 17217533 Molecular analysis of hepatitis B virus "a" determinant in asymptomatic and symptomatic Mexican carriers
Mutation
125 17259736 G1862T mutation among hepatitis B virus-infected individuals: association with viral genotypes and disease outcome in Kolkata, Eastern India
Mutation
126 17352033 Fatal liver failure caused by reactivation of lamivudine-resistant hepatitis B virus: a case report
Mutation
127 17573951 Changes in viral loads of lamivudine-resistant mutants during entecavir therapy
Mutation
128 17576389 Long-term surveillance of haematopoietic stem cell recipients with resolved hepatitis B: high risk of viral reactivation even in a recipient with a vaccinated donor
Mutation
129 17591025 In vitro susceptibility of adefovir-associated hepatitis B virus polymerase mutations to other antiviral agents
Mutation
130 17601044 [Impact of amino acid sequence variation of a determinant(s) on the antigenic properties of hepatitis B virus HBsAg]
Mutation
131 17607789 Virological features of hepatitis B virus-associated nephropathy in Japan
Mutation
132 17622616 Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53
Mutation
133 17666334 [Construction of whole-genome lamivudine-resistant hepatitis B virus mutant and its replication and expression in HepG2 cells]
Mutation
134 17682718 [A case of chronic hepatitis B with primary adefovir resistance]
Mutation
135 17692425 Pooled analysis of amino acid changes in the HBV polymerase in patients from four major adefovir dipivoxil clinical trials
Mutation
136 17711443 Molecular epidemiological study of hepatitis B virus in Thailand based on the analysis of pre-S and S genes
Mutation
137 17763322 Replicative competence of the T131I, K141E, and G145R surface variants of hepatitis B Virus
Mutation
138 17900990 The high prevalence of the I27 mutant HBcAg18-27 epitope in Chinese HBV-infected patients and its cross-reactivity with the V27 prototype epitope
Mutation
139 17935165 Successful treatment of an entecavir-resistant hepatitis B virus variant
Mutation
140 18008227 Hepatitis B virus containing the I233V mutation in the polymerase reverse-transcriptase domain remains sensitive to inhibition by adefovir
Mutation
141 18205223 Naturally occurring MHR variants in Turkish patients infected with hepatitis B virus
Mutation
142 18283732 [Algorithm of serologic screening and assessment of prevalence of serologically meaningful mutations of HBsAg in hepatitis B virus carriers]
Mutation
143 18331765 Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure
Mutation
144 18343830 Effect of basal core promoter and pre-core mutations on hepatitis B virus replication
Mutation
145 18373168 Hepatitis B caused by a hepatitis B surface antigen escape mutant
Mutation
146 18431229 Viral persistence after liver transplantation for hepatitis B virus: a cross-sectional study
Mutation
147 18434744 A unique amino acid substitution, L215Q, in the hepatitis B virus small envelope protein of a genotype F isolate that inhibits secretion of hepatitis B virus subviral particles
Mutation
148 18435459 Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance
Mutation
149 18647234 Expression of hepatitis B virus nuclear core antigen in young cirrhotic patients is associated with an unfavourable long-term outcome
Mutation
150 18649345 Envelope protein variability among HBV-Infected asymptomatic carriers and immunized children with breakthrough infections
Mutation
151 18713056 Supportive role played by precore and preS2 genomic changes in the establishment of lamivudine-resistant hepatitis B virus
Mutation
152 18765256 Understanding the molecular basis of HBV drug resistance by molecular modeling
Mutation
153 18803358 Clinical, virologic and phylogenetic features of hepatitis B infection in Iranian patients
Mutation
154 18813870 Mutation spectra of the surface-protein-coding region of the HBV genome in HBV-vaccinated and non-vaccinated individuals in Hungary
Mutation
155 18837083 Virologic characteristics of hepatitis B virus in patients infected via maternal-fetal transmission
Mutation
156 18952249 Analysis of hepatitis B virus X gene phylogeny, genetic variability and its impact on pathogenesis: implications in Eastern Indian HBV carriers
Mutation
157 19028525 Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir
Mutation
158 19041149 The profile of mutational clusters associated with lamivudine resistance can be constrained by HBV genotypes
Mutation
159 19196007 A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly
Mutation
160 19212700 Influence of HBV gene heterogeneity on the failure of immunization with HBV vaccines in eastern China
Mutation
161 19222103 Hepatitis B virus mutations potentially conferring adefovir/tenofovir resistance in treatment-naive patients
Mutation
162 19263474 The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains
Mutation
163 19272629 Association between genomic heterogeneity of hepatitis B virus and intrauterine infection
Mutation
164 19302908 Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues
Mutation
165 19327810 Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations
Mutation
166 19382250 Frequent detection of hepatitis B virus variants associated with lamivudine resistance in treated South African patients infected chronically with different HBV genotypes
Mutation
167 19383566 trans-Complementation of HBV rtM204I mutant replication by HBV wild-type polymerase
Mutation
168 19386834 Complete genome sequence and phylogenetic relatedness of hepatitis B virus isolates in Papua, Indonesia
Mutation
169 19413519 Perinatal transmission of hepatitis B virus: an Australian experience
Mutation
170 19486254 Characterization of hepatitis B virus reverse transcriptase sequences in Chinese treatment naive patients
Mutation
171 19550344 Monitoring of therapy in patients with chronic hepatitis B virus
Mutation
172 19570861 A function essential to viral entry underlies the hepatitis B virus "a" determinant
Mutation
173 19586679 Prevalence, viral replication efficiency and antiviral drug susceptibility of rtQ215 polymerase mutations within the hepatitis B virus genome
Mutation
174 19626618 A serological and molecular survey of hepatitis B in children 15 years after inception of the national hepatitis B vaccination program in eastern China
Mutation
175 19669299 Primary resistance, multidrug resistance, and cross-resistance pathways in HBV as a consequence of treatment failure
Mutation
176 19691824 Hepatitis B virus genotypes/subgenotypes in voluntary blood donors in Makassar, South Sulawesi, Indonesia
Mutation
177 19710138 Functional surfaces of the hepatitis B virus capsid
Mutation
178 19759159 The pre-S1 and antigenic loop infectivity determinants of the hepatitis B virus envelope proteins are functionally independent
Mutation
179 19812261 Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
Mutation
180 19889778 Differential impact of immune escape mutations G145R and P120T on the replication of lamivudine-resistant hepatitis B virus e antigen-positive and -negative strains
Mutation
181 19940057 Molecular characteristics of occult hepatitis B virus from blood donors in southeast China
Mutation
182 19950231 PreS deletion mutations of hepatitis B virus in chronically infected patients with simultaneous seropositivity for hepatitis-B surface antigen and anti-HBS antibodies
Mutation
183 20034521 Characterization of potential antiviral resistance mutations in hepatitis B virus reverse transcriptase sequences in treatment-naive Chinese patients
Mutation
184 20068337 Impacts of vaccination on hepatitis B viral infections in Korea over a 25-year period
Mutation
185 20074155 Prevalence and clinical characterization of patients with acute hepatitis B induced by lamivudine-resistant strains
Mutation
186 20087936 Molecular evolutionary analysis and mutational pattern of full-length genomes of hepatitis B virus isolated from Belgian patients with different clinical manifestations
Mutation
187 20169198 Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir
Mutation
188 20173647 T1653 mutation in the enhancer II region of the hepatitis B virus genome in southern African Blacks with hepatocellular carcinoma
Mutation
189 20184927 Molecular characteristics and functional analysis of full-length hepatitis B virus quasispecies from a patient with chronic hepatitis B virus infection
Mutation
190 20196797 Diversity of hepatitis B virus infecting Malaysian candidate blood donors is driven by viral and host factors
Mutation
191 20210630 No increase in prevalence of hepatitis B surface antigen mutant in a population of children and adolescents who were fully covered by universal infant immunization
Mutation
192 20222172 Establishment of a new quantitative detection approach to adefovir-resistant HBV and its clinical application
Mutation
193 20231988 Expression of Hepatitis B virus surface antigen (HBsAg) from genotypes A, D and F and influence of amino acid variations related or not to genotypes on HBsAg detection
Mutation
194 20337225 T3098C and T53C mutations of HBV genotype C is associated with HBV infection progress
Mutation
195 20347609 Establishment of an HBsAg mixed titer performance panel and HBsAg working standard for quality control of HBsAg diagnostic kits in Korea
Mutation
196 20367795 Four-year study of lamivudine and adefovir combination therapy in lamivudine-resistant hepatitis B patients: influence of hepatitis B virus genotype and resistance mutation pattern
Mutation
197 20374224 Main mutations in the hepatitis B virus basic core promoter (A1762T/G1764A) before HBeAg loss are markers that identify patients who will require long-term treatment
Mutation
198 20409073 Hepatitis B virus transfusion risk in China: proficiency testing for the detection of hepatitis B surface antigen
Mutation
199 20492719 A novel nucleotide insertion in S gene of hepatitis B virus in a chronic carrier
Mutation
200 20513074 Molecular and clinical characteristics of hepatitis B virus in Korea
Mutation
201 20546502 Factors associated with vaccine failure and vertical transmission of hepatitis B among a cohort of Canadian mothers and infants
Mutation
202 20553432 National survey of hepatitis B virus (HBV) polymorphism in asymptomatic HBV blood donors from 1999 to 2007 in France
Mutation
203 20572086 Molecular epidemiological study of hepatitis B virus among migrant workers from Cambodia, Laos, and Myanmar to Thailand
Mutation
204 20573234 Infection with hepatitis B virus carrying novel pre-S/S gene mutations in female siblings vaccinated at birth: two case reports
Mutation
205 20580309 Acute hepatitis B infection associated with drug-resistant hepatitis B virus
Mutation
206 20586936 rtE218G, a novel hepatitis B virus mutation with resistance to adefovir dipivoxil in patients with chronic hepatitis B
Mutation
207 20595500 Serologic and molecular characteristics of hepatitis B virus among school children in East Java, Indonesia
Mutation
208 20638744 HBV reactivation after fludarabine chemotherapy identified on investigation of suspected transfusion-transmitted Hepatitis B virus
Mutation
209 20875460 Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
Mutation
210 20881037 Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site
Mutation
211 20887378 Impact of hepatitis B e antigen-suppressing mutations on the replication efficiency of entecavir-resistant hepatitis B virus strains
Mutation
212 20932594 Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion
Mutation
213 20937597 A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads
Mutation
214 20959021 Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon alpha
Mutation
215 21087462 Prediction of conformational changes by single mutation in the hepatitis B virus surface antigen (HBsAg) identified in HBsAg-negative blood donors
Mutation
216 21181917 Molecular characterization of hepatitis B virus isolates from Zimbabwean blood donors
Mutation
217 21311172 Antiviral resistance mutations and genotype-associated amino acid substitutions in treatment-naive hepatitis B virus-infected individuals from the Indian subcontinent
Mutation
218 21360549 Impact of universal vaccination on intrafamilial transmission of hepatitis B virus
Mutation
219 21494570 Geographical and ethnic distribution of the HBV C/D recombinant on the Qinghai-Tibet Plateau
Mutation
220 21503905 Full genome characterization of hepatitis B virus strains from blood donors in Iran
Mutation
221 21503906 Clinical course and predictive factors of virological response in long-term lamivudine plus adefovir dipivoxil combination therapy for lamivudine-resistant chronic hepatitis B patients
Mutation
222 21520137 Analysis of carriers of hepatitis B virus from a tertiary referral hospital: does the viral load change during the natural course of infection?
Mutation
223 21665530 Quantification of complex precore mutations of hepatitis B virus by SimpleProbe real time PCR and dual melting analysis
Mutation
224 21685535 De novo activation of HBV with escape mutations from hepatitis B surface antibody after living donor liver transplantation
Mutation
225 21723325 Development and validation of a hepatitis B virus DNA sequencing assay for assessment of antiviral resistance, viral genotype and surface antigen mutation status
Mutation
226 21765983 Genomic analysis of hepatitis B virus reveals antigen state and genotype as sources of evolutionary rate variation
Mutation
227 21831732 Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
Mutation
228 21840251 Mutations in hepatitis B virus DNA from patients with coexisting HBsAg and anti-HBs
Mutation
229 22001270 Identification of hepatitis B virus rtS117F substitution as a compensatory mutation for rtM204I during lamivudine therapy
Mutation
230 22097597 [Detection and analysis of gene polymorphism in hepatitis B virus C region]
Mutation
231 22138369 Late hepatitis B virus reactivation after lamivudine prophylaxis interruption in an anti-HBs-positive and anti-HBc-negative patient treated with rituximab-containing therapy
Mutation
232 22138714 Prevalence, virology and antiviral drugs susceptibility of hepatitis B virus rtN238H polymerase mutation from 1865 Chinese patients with chronic hepatitis B
Mutation
233 22173170 Quantitative dynamics of hepatitis B basal core promoter and precore mutants before and after HBeAg seroconversion
Mutation
234 22233650 Hepatitis B surface gene 145 mutant as a minor population in hepatitis B virus carriers
Mutation
235 22274739 Mutations in the S gene region of hepatitis B virus genotype D in Golestan Province-Iran
Mutation
236 22363813 Large fragment pre-S deletion and high viral load independently predict hepatitis B relapse after liver transplantation
Mutation
237 22383959 A high variability of mixed infections and recent recombinations of hepatitis B virus in Laos
Mutation
238 22500577 Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China
Mutation
239 22510694 Convergence and coevolution of hepatitis B virus drug resistance
Mutation
240 22669316 Molecular epidemiological study of hepatitis B virus in blood donors from five Chinese blood centers
Mutation
241 22711345 Molecular analysis of hepatitis B virus associated with vaccine failure in infants and mothers: a case-control study in Thailand
Mutation
242 22882650 Prevalence and significance of Hepatitis B reverse transcriptase mutants in different disease stages of untreated patients
Mutation
243 22892524 Evolution of adefovir-resistant HBV polymerase gene variants after switching to tenofovir disoproxil fumarate monotherapy
Mutation
244 22967103 Mutations associated with occult hepatitis B virus infection result in decreased surface antigen expression in vitro
Mutation
245 22967107 Specific primer sets used to amplify by PCR the hepatitis B virus overlapping S/Pol region select different viral variants
Mutation
246 23114756 Low-level persistence of drug resistance mutations in hepatitis B virus-infected subjects with a past history of Lamivudine treatment
Mutation
247 23254298 Hepatitis B virus surface antigen (HBsAg)-positive and HBsAg-negative hepatitis B virus infection among mother-teenager pairs 13 years after neonatal hepatitis B virus vaccination
Mutation
248 23265059 [The panels of serums, containing various subtypes and mutant forms of HBsAg, to evaluate the diagnostics sensitivity of kits oa reagents detecting HBsAg]
Mutation
249 23296324 Epidemiology of HBV S-gene mutants in the Liguria Region, Italy: Implications for surveillance and detection of new escape variants
Mutation
250 23336976 High prevalence of hepatitis B virus genotype C/C1 in the Minangkabau ethnic group in Indonesia
Mutation
251 23346148 Investigation of DNA sequence in the Basal core promoter, precore, and core regions of hepatitis B virus from Tunisia shows a shift in genotype prevalence
Mutation
252 23408582 High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates
Mutation
253 23409946 Characterization of antiviral resistance mutations among the Eastern Indian Hepatitis B virus infected population
Mutation
254 23432545 Molecular epidemiology of hepatitis B in the Indigenous people of northern Australia
Mutation
255 23454647 Combination of allele-specific detection techniques to quantify minority resistance variants in hepatitis B infection: a novel approach
Mutation
256 23547448 [Significance of the double mutations of C1673T/C1799G in HBV C promoter]
Mutation
257 23679074 Late HBsAg seroreversion of mutated hepatitis B virus after bone marrow transplantation
Mutation
258 23796863 Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen
Mutation
259 23804383 Ultrasensitive amplification refractory mutation system real-time PCR (ARMS RT-PCR) assay for detection of minority hepatitis B virus-resistant strains in the era of personalized medicine
Mutation
260 23903967 Molecular characterisation of hepatitis B virus in the resident Chinese population in Panama City
Mutation
261 24006443 Change in hepatitis B virus large surface antigen variant prevalence 13 years after implementation of a universal vaccination program in China
Mutation
262 24031448 Prevalence of the precore G1896A mutation in Chinese patients with e antigen negative hepatitis B virus infection and its relationship to pre-S1 antigen
Mutation
263 24053482 Decreased antigenicity profiles of immune-escaped and drug-resistant hepatitis B surface antigen (HBsAg) double mutants
Mutation
264 24076590 Construction and expression of hepatitis B surface antigen escape variants within the "a" determinant by site directed mutagenesis
Mutation
265 24118725 HBV clinical isolates expressing adefovir resistance mutations show similar tenofovir susceptibilities across genotypes B, C and D
Mutation
266 24157033 Analysis of S gene mutation of the hepatitis B virus in adult liver transplant recipients showing resistance to hepatitis B immunoglobulin therapy
Mutation
267 24165277 Detection of lamivudine-resistant variants and mutations related to reduced antigenicity of HBsAg in individuals from the cities of Santos and Sao Paulo, Brazil
Mutation
268 24249691 Variability in the precore and core promoter region of the hepatitis B virus genome
Mutation
269 24265811 High endemicity and low molecular diversity of hepatitis B virus infections in pregnant women in a rural district of North Cameroon
Mutation
270 24273041 The impact of hepatitis B virus precore/core gene carboxyl terminal mutations on viral biosynthesis and the host immune response
Mutation
271 24282423 The N-Glycosylation Modification of LHBs (Large Surface Proteins of HBV) Effects on Endoplasmic Reticulum Stress, Cell Proliferation and its Secretion
Mutation
272 24329944 Short duration of lamivudine for the prevention of hepatitis B virus transmission in pregnancy: lack of potency and selection of resistance mutations
Mutation
273 24342744 Mutations in HBV DNA polymerase associated with nucleos(t)ide resistance are rare in treatment-naive patients
Mutation
274 24369590 [Clinical evaluation of a newly developed high-sensitive detection of hepatitis B virus surface antigen by a semi-automated immune complex transfer chemiluminescent enzyme immunoassay]
Mutation
275 24379746 Naturally occurring hepatitis B virus B-cell and T-cell epitope mutants in hepatitis B vaccinated children
Mutation
276 24587198 Establishment of real time allele specific locked nucleic acid quantitative PCR for detection of HBV YIDD (ATT) mutation and evaluation of its application
Mutation
277 24632784 Analysis of complete nucleotide sequences of Angolan hepatitis B virus isolates reveals the existence of a separate lineage within genotype E
Mutation
278 24710668 Screening and identification of a novel adefovir dipivoxil resistance associated mutation, rtN236V, of HBV from a large cohort of HBV-infected patients
Mutation
279 24777553 Amino acid polymorphism in the reverse transcriptase region of hepatitis B virus and the relationship with nucleos(t)ide analogues treatment for preventing mother-to-infant transmission
Mutation
280 24797477 Molecular epidemiological study of hepatitis B virus genotypes in Southwest, China
Mutation
281 25323975 Prevalence of mutations in basal core promoter and precore region of hepatitis B virus in vaccinated and nonvaccinated individuals of the aboriginal Nicobarese tribe of Car Nicobar Island, India
Mutation
282 25333524 Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma
Mutation
283 25351410 Single-nucleotide substitution of Hepatitis B virus in intrauterine infection
Mutation
284 25418031 Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression
Mutation
285 25493022 Resistant mutants induced by adefovir dipivoxil in hepatitis B virus isolates
Mutation
286 25503289 Subgenotypes and mutations in the s and polymerase genes of hepatitis B virus carriers in the West Bank, palestine
Mutation
287 25567052 Hepatitis B Virus Core Promoter A1762T/G1764A (TA)/T1753A/T1768A Mutations Contribute to Hepatocarcinogenesis by Deregulating Skp2 and P53
Mutation
288 25593470 Mutations of pre-core and basal core promoter before and after hepatitis B e antigen seroconversion
Mutation
289 25737728 S gene mutants occurrence among hepatitis B carriers in malaysia
Mutation
290 25741368 Mutations of Basal core promoter and precore regions in hepatitis B virus genotypes B and C
Mutation
291 25828947 Upregulation of endoplasmic reticulum stress and reactive oxygen species by naturally occurring mutations in hepatitis B virus core antigen
Mutation
292 25890025 Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles
Mutation
293 26074702 Precore/basal core promoter mutants quantification throughout phases of hepatitis B virus infection by Simpleprobe
Mutation
294 26079809 Increased occurrence of mutant rtI233V of HBV in patients receiving adefovir therapy
Mutation
295 26148052 Occult Hepatitis B Virus Infection in Nigerian Blood Donors and Hepatitis B Virus Transmission Risks
Mutation
296 26209374 Performance of HBsAg point-of-care tests for detection of diagnostic escape-variants in clinical samples
Mutation
297 26283552 Detection and circulation of hepatitis B virus immune escape mutants among asymptomatic community dwellers in Ibadan, southwestern Nigeria
Mutation
298 26300928 YMDD Motif Mutation Profile Among Patients Receiving Liver Transplant Due to Hepatitis B Virus Infection With Long Term Lamivudine/Immunoglobulin Therapy
Mutation
299 26384943 Occult hepatitis B virus infection and S gene escape mutants in HIV-infected patients after hepatitis B virus vaccination
Mutation
300 26420301 Hepatitis B surface gene variants isolated from blood donors with overt and occult HBV infection in north eastern Egypt
Mutation
301 26515673 Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones
Mutation
302 26612031 Epidemiology study of HBV genotypes and antiviral drug resistance in multi-ethnic regions from Western China
Mutation
303 26919858 Reactivation of resolved hepatitis B virus infection with immune escape mutations after long-term corticosteroid therapy
Mutation
304 26997220 Surface gene variants of hepatitis B Virus in Saudi Patients
Mutation
305 27131009 Serologic and molecular characteristics of hepatitis B virus infection in vaccinated schizophrenia patients in China
Mutation
306 27133305 Discordant diagnostic results due to a hepatitis B virus T123A HBsAg mutant
Mutation
307 27280884 Impact of Universal Hepatitis B Vaccination on Prevalence, Infection-Associated Morbidity and Mortality, and Circulation of Immune Escape Variants in Russia
Mutation
308 27402524 Hepatitis B Virus Infection in Indonesia 15 Years After Adoption of a Universal Infant Vaccination Program: Possible Impacts of Low Birth Dose Coverage and a Vaccine-Escape Mutant
Mutation
309 27422771 The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients
Mutation
310 27492206 Different Variants in Reverse Transcriptase Domain Determined by Ultra-deep Sequencing in Treatment-naive and Treated Indonesian Patients Infected with Hepatitis B Virus
Mutation
311 27613286 Low prevalence of hepatitis B vaccine escape mutants among individuals born after the initiation of a nationwide vaccination program in Iran
Mutation
312 27652086 Molecular epidemiology of hepatitis B virus isolated from Bangladesh
Mutation
313 27792585 Comparison of Detection Rate and Mutational Pattern of Drug-Resistant Mutations Between a Large Cohort of Genotype B and Genotype C Hepatitis B Virus-Infected Patients in North China
Mutation
314 27808472 A novel hepatitis B virus subgenotype D10 circulating in Ethiopia
Mutation
315 27882062 Genotyping and Mutation Pattern in the Overlapping MHR Region of HBV Isolates in Southern Khorasan, Eastern Iran
Mutation
316 27920641 Severe de novo Hepatitis B Recovered from Late-Onset Liver Insufficiency with Prolonged Ascites and Hypoalbuminemia due to Hepatitis B Virus Genotype Bj with Precore Mutation
Mutation
317 27998385 Hepatitis B Immunoprophylactic Failure and Characteristics of the Hepatitis B Virus Gene in Mother-Infant Pairs in Parts of China
Mutation
318 28017671 Analysis of the prevalence of drug-resistant hepatitis B virus in patients with antiviral therapy failure in a Chinese tertiary referral liver centre (2010-2014)
Mutation
319 28325923 Clinical features and viral quasispecies characteristics associated with infection by the hepatitis B virus G145R immune escape mutant
Mutation
320 28392234 Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy
Mutation
321 28401569 Influences on viral replication and sensitivity to GLS4, a HAP compound, of naturally occurring T109/V124 mutations in hepatitis B virus core protein
Mutation
322 28566379 Discovery and Mechanistic Study of Benzamide Derivatives That Modulate Hepatitis B Virus Capsid Assembly
Mutation
323 28582431 Hepatitis B genotypes and surface antigen mutants present in Pakistani blood donors
Mutation
324 28607644 Prevalence and Characteristics of Precore Mutation in Iran and Its Correlation with Genotypes of Hepatitis B
Mutation
325 28647474 Antiviral profiling of the capsid assembly modulator BAY41-4109 on full-length HBV genotype A-H clinical isolates and core site-directed mutants in vitro
Mutation
326 28673869 Impact of deletions and mutations in Hepatitis B virus envelope proteins on serological profile and clinical evolution
Mutation
327 28749433 HBV Drug Resistance Substitutions Existed before the Clinical Approval of Nucleos(t)ide Analogues: A Bioinformatic Analysis by GenBank Data Mining
Mutation
328 28751727 Temporal trend of hepatitis B surface mutations in the post-immunization period: 9 years of surveillance (2005-2013) in eastern China
Mutation
329 28753615 Clustering infection of hepatitis B virus genotype B4 among residents in Vietnam, and its genomic characters both intra- and extra-family
Mutation
330 28806922 Hepatitis B reactivation characterized by HBsAg negativity and anti-HbsAg antibodies persistence in haematopoietic stem cell transplanted patient after lamivudine withdrawal
Mutation
331 28939157 Molecular evolution of hepatitis B vaccine escape variants in China, during 2000-2016
Mutation
332 29016603 Characterization of hepatitis B virus in Amerindian children and mothers from Amazonas State, Colombia
Mutation
333 29039614 Substitutions of rtL228 and/or L229 are involved in the regulation of replication and HBsAg secretion in hepatitis B virus, and do not affect susceptibility to nucleos(t)ide analogs
Mutation
334 29096158 Human hepatocytes apoptosis induced by replication of hepatitis B virus subgenotypes F1b and F4: Role of basal core promoter and preCore mutations
Mutation
335 29119303 Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016)
Mutation
336 29248936 Patients with Coexistence of Circulating Hepatitis B Surface Antigen and Its Antibody May Have a Strong Predisposition to Virus Reactivation During Immunosuppressive Therapy: A Hypothesis
Mutation
337 29414186 Substantial variation in the hepatitis B surface antigen (HBsAg) in hepatitis B virus (HBV)-positive patients from South Africa: Reliable detection of HBV by the Elecsys HBsAg II assay
Mutation
338 29479565 Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer
Mutation
339 29604477 Impact of immune escape mutations and N-linked glycosylation on the secretion of hepatitis B virus virions and subviral particles: Role of the small envelope protein
Mutation
340 29609638 The truncated mutant HBsAg expression increases the tumorigenesis of hepatitis B virus by regulating TGF-beta/Smad signaling pathway
Mutation
341 29628773 The mutation of hepatitis B virus and the prognosis of hepatocellular carcinoma after surgery: a pilot study
Mutation
342 29629487 Quasispecies characters of hepatitis B virus in immunoprophylaxis failure infants
Mutation
343 29630974 Hepatitis B virus rtA181T/sW172non-stop mutation may increase resistance fold to adefovir- and entecavir-resistant mutants compared to rtA181T/sW172* mutation
Mutation
344 29654894 Trends in hepatitis B virus resistance to nucleoside/nucleotide analogues in North China from 2009-2016: A retrospective study
Mutation
345 29843851 Fulminant hepatitis B virus (HBV) infection in an infant following mother-to-child transmission of an e-minus HBV mutant: Time to relook at HBV prophylaxis in South African infants
Mutation
346 30377627 Hepatitis B Virus (HBV) Infection and Re-activation During Nucleos(t)ide Reverse Transcriptase Inhibitor-Sparing Antiretroviral Therapy in a High-HBV Endemicity Setting
Mutation
347 30382563 Molecular characterization of hepatitis B virus in blood donors in Botswana
Mutation
348 30417200 Analysis of fitness differences of hepatitis B virus genotypes D and F using a cotransfection assay
Mutation
349 30570771 Hepatitis B virus in Mar del Plata, Argentina: Genomic characterization and evolutionary analysis of subgenotype F1b
Mutation
350 30584239 Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection
Mutation
351 30706588 HBV T1719G mutation reduced HBV replication through mutant Enh II and HBx protein in vitro
Mutation
352 30866789 Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice
Mutation
353 31046787 A substitution in the pre-S1 promoter region is associated with the viral regulation of hepatitis B virus
Mutation
354 31147594 Potential resistant mutations within HBV reverse transcriptase sequences in nucleos(t)ide analogues-experienced patients with hepatitis B virus infection
Mutation
355 31248149 Frequency of Hepatitis B Virus Resistance Mutations in Women Using Tenofovir Gel as Pre-Exposure Prophylaxis
Mutation
356 31434918 High possibility of hepatocarcinogenesis in HBV genotype C1 infected Cambodians is indicated by 340 HBV C1 full-genomes analysis from GenBank
Mutation
357 31558731 Prevalence of Hepatitis B Virus Infection in Shenzhen, China, 2015-2018
Mutation
358 31682960 Detection of circulating hepatitis B virus immune escape and polymerase mutants among HBV-positive patients attending Institut Pasteur de Bangui, Central African Republic
Mutation
359 31752732 Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission
Mutation
360 31952213 PreS1 Mutations Alter the Large HBsAg Antigenicity of a Hepatitis B Virus Strain Isolated in Bangladesh
Mutation
361 32102257 A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in Vitro
Mutation
362 32124248 Conservative Evolution of Hepatitis B Virus Precore and Core Gene During Immune Tolerant Phase in Intrafamilial Transmission
Mutation
363 32519312 Spontaneous reactivation of hepatitis B virus with S gene mutations in an elderly patient with diabetic nephropathy
Mutation
364 32532295 Complete genome analysis of hepatitis B virus in Qinghai-Tibet plateau: the geographical distribution, genetic diversity, and co-existence of HBsAg and anti-HBs antibodies
Mutation
365 32735901 Revisiting HBV resistance to entecavir with a phenotypic approach
Mutation
366 32894807 Characterization of Hepatitis B virus polymerase mutations A194T and CYEI and tenofovir disoproxil fumarate or tenofovir alafenamide resistance
Mutation
367 32978866 Case of hepatitis B virus reactivation after ibrutinib therapy in which the patient remained negative for hepatitis B surface antigens throughout the clinical course
Mutation
368 33055418 Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers
Mutation
369 33090103 Molecular epidemiology of Hepatitis B virus, Hepatitis C virus, and Hepatitis D virus in general population of Afghanistan
Mutation
370 33187530 Seroprevalence and genotypic characterization of HBV among low risk voluntary blood donors in Nairobi, Kenya
Mutation
371 33468062 Molecular characteristics of HBV infection among blood donors tested HBsAg reactive in a single ELISA test in southern China
Mutation
372 33491423 Prevalence of Hepatitis B Virus Infection Among Voluntary Blood Donors from the Northeastern Region of Iran: Genotyping, Viral Load Characterization and Drug Resistance Prediction
Mutation
373 33857724 LCR based quick detection of hotspot G1896A mutation in patients with different spectrum of hepatitis B
Mutation
374 33903819 Entecavir resistance in a patient with treatment-naive HBV: A case report
Mutation
375 33959934 Spontaneous reactivation of hepatitis B virus with a frameshift mutation in the precore region in an elderly hepatitis B virus carrier with lifestyle-related diseases
Mutation
376 34076480 Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations
Mutation
377 34210073 Detection of Q129H Immune Escape Mutation in Apparently Healthy Hepatitis B Virus Carriers in Southwestern Nigeria
Mutation
378 34214504 Evolution and phenotypic characterization of whole HBV genome in compliant patients experiencing unexplained entecavir treatment failure
Mutation
379 34234632 Hepatitis B virus genetic heterogeneity and drug resistance among jaundiced patients at Coast General Teaching and Referral Hospital, Mombasa County, Kenya
Mutation
380 34755817 Hepatitis B in the Northwestern region of Sao Paulo State: genotypes and resistance mutations
Mutation
381 34902556 Analysis of entire hepatitis B virus genomes reveals reversion of mutations to wild type in natural infection, a 15 year follow-up study
Mutation
382 34982798 Genetic diversity in enhancer II region of HBV genotype D and its association with advanced liver diseases
Mutation
383 35102169 Dried blood spot sampling for hepatitis B virus quantification, sequencing and mutation detection
Mutation
384 35223517 The Effects and Underlying Mechanisms of Hepatitis B Virus X Gene Mutants on the Development of Hepatocellular Carcinoma
Mutation
385 35271684 Prevalence, genotype distribution and mutations of hepatitis B virus and the associated risk factors among pregnant women residing in the northern shores of Persian Gulf, Iran
Mutation
386 35644506 Characterization of the tenofovir resistance-associated mutations in the hepatitis B virus isolates across genotypes A to D
Mutation
387 35715756 Molecular evaluation of hepatitis B virus infection and predominant mutations of pre-core, basal core promoter and S regions in an Iranian population with type 2 diabetes mellitus: a case-control study
Mutation
388 35805045 HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling
Mutation
389 35884942 Susceptibility of Drug Resistant Hepatitis B Virus Mutants to Besifovir
Mutation
390 36037476 Establishment and Characterization of an HBV Viral Spread and Infectious System following Long-Term Passage of an HBV Clinical Isolate in the Primary Human Hepatocyte and Fibroblast Coculture System
Mutation
391 36167927 Core promoter mutation of nucleotides A1762T and G1764A of hepatitis B virus increases core promoter transactivation by hepatocyte nuclear factor 1
Mutation
392 36721514 The mutations frequency of enhancer II/HBx regions of hepatitis B virus in acutely infected Iranian patients: a cross-sectional study
Mutation
393 36815535 Comparative analysis of hepatitis B virus infections in blood donors born before and after the implementation of universal HBV vaccination in southern China
Mutation
394 36825877 Different mutation rates in the basal core promoter and precore regions between hepatitis B virus subgenotype F1b clusters
Mutation
395 36919573 C2729T mutation associated with HBV mother-to-child transmission reduces HBV production via suppressing LHBs expression
Mutation
396 37015318 Decreased expression of HBV surface antigen (HBsAg) with sK122R and sV96A co-mutation is associated with an ineffective antibody response in a chronic hepatitis B patient
Mutation
397 37436414 [Frequency of drug resistance and immune escape mutations in the hepatitis B virus genome detected in pregnant women in the Republic of Guinea]
Mutation
398 37632070 Possible Association between Genetic Diversity of Hepatitis B Virus and Its Effect on the Detection Rate of Hepatitis B Virus DNA in the Placenta and Fetus
Mutation
399 37646026 Host immunity and HBV S gene mutation in HBsAg-negative HBV-infected patients
Mutation
400 37703117 Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Mutation
401 37771603 The central nervous system is a potential reservoir and possible origin of drug resistance in hepatitis B infection
Mutation
402 37963165 Genetic diversity, haplotype analysis, and prevalence of Hepatitis B virus MHR mutations among isolates from Kenyan blood donors
Mutation
403 38004634 Phylogenetic Analysis and Emerging Drug Resistance against Different Nucleoside Analogues in Hepatitis B Virus Positive Patients
Mutation
404 38005866 Detection of Immune Escape and Basal Core Promoter/Precore Gene Mutations in Hepatitis B Virus Isolated from Asymptomatic Hospital Attendees in Two Southwestern States in Nigeria
Mutation
405 38349448 Characterization of a breakthrough vaccine escape strain associated with overt hepatitis B virus infection
Mutation
406 38492851 Precore mutation enhances viral replication to facilitate persistent infection especially in HBeAg-negative patients
Mutation
407 38564936 Characterization of BCP/PreC/C region quasispecies in treatment-naive patients with different phases of HBV infection using next-generation sequencing
Mutation
408 38632180 Characterization of mutations in hepatitis B virus DNA isolated from Japanese HBsAg-positive blood donors in 2021 and 2022
Mutation
409 38654327 Effect of S-region mutations on HBsAg in HBsAg-negative HBV-infected patients
Mutation
410 38679167 The lack of HBsAg secretion does neither facilitate induction of antiviral T cell responses nor Hepatitis B Virus clearance in mice
Mutation
411 38748198 Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection
Mutation
412 39078064 Impaired HBsAg release and antiproliferative/antioxidant cell regulation by HBeAg-negative patient isolates reflects an evolutionary process
Mutation
413 39499382 Molecular epidemiology and genetic characterization of hepatitis B virus in two major provinces of Pakistan
Mutation
414 39525359 Diversity of HBV genotypes and their association with precore/basal core mutations among HBsAg-positive patients in Ibadan, Nigeria
Mutation
415 39749680 Wild-Type and rtA181T/sW172* Mutant Strains of Hepatitis B Virus Drive Hepatocarcinogenesis via Distinct GRP78-Mediated ER Stress Pathways
Mutation
416 39787208 Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene
Mutation
417 39977392 The sV184A Variant in HBsAg Specific to HBV Subgenotype C2 Leads to Enhanced Viral Replication and Apoptotic Cell Death Induced by PERK-eIF2alpha-CHOP-Mediated ER Stress
Mutation
418 40025815 The first case of transfusion-transmitted hepatitis B virus genotype I in Japan
Mutation
419 40055372 The pattern change of hepatitis B virus genetic diversity in Northwestern Tanzania
Mutation
420 40102552 Distinct phylogeographic distributions and frequencies of precore and basal core promoter mutations between HBV subgenotype C1 rt269L and rt269I types
Mutation
421 40283226 Immune Escape and Drug Resistance Mutations in Patients with Hepatitis B Virus Infection: Clinical and Epidemiological Implications
Mutation
422 40310552 Genotypes, subtypes, and genetic variability of hepatitis B virus from blood donors in Timor-Leste
Mutation
423 40358045 High Genetic Variability of Hepatitis B Virus in Blood Donors With Surface Antigen Positive But DNA Negative in Southern China
Mutation
424 19574418 Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis
Mutation
425 19664630 Hepatitis B virus core variants modify natural course of viral infection and hepatocellular carcinoma progression
Mutation
426 19998495 Clinical relevance and public health significance of hepatitis B virus genomic variations
Mutation
427 20160279 Distribution and hepatocellular carcinoma-related viral properties of hepatitis B virus genotypes in Mainland China: a community-based study
Mutation
428 21104161 Association of novel mutations and haplotypes in the preS region of hepatitis B virus with hepatocellular carcinoma
Mutation
429 22014121 Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients
Mutation
430 24973814 Mother-to-child transmission of hepatitis B virus: evolution of hepatocellular carcinoma-related viral mutations in the post-immunization era
Mutation
431 30702819 Analyses of the Genetic Diversities and Mutations of the Hepatitis B Virus Genome BCP/Pre C Region
Mutation
432 34534105 Nucleotide variants in hepatitis B virus preS region predict the recurrence of hepatocellular carcinoma
Mutation
433 30406036 The Correlation Between Hepatitis B Virus Precore/Core Mutations and the Progression of Severe Liver Disease
Mutation
434 31501793 Comparison of pre-S1/S2 variations of hepatitis B virus between asymptomatic carriers and cirrhotic/hepatocellular carcinoma-affected individuals
Mutation
435 22313146 Reactivation of hepatitis B virus with mutated hepatitis B surface antigen in a liver transplant recipient receiving a graft from an antibody to hepatitis B surface antigen- and antibody to hepatitis B core antigen-positive donor
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.