Overview of HPV associated Uterine Cervical Neoplasms

ID Literature Title Group
1 35086475 Genetic diversity in L1 ORF of human papillomavirus in women with cervical cancer with and without human immunodeficiency virus in Botswana and Kenya
Mutation
2 32986347 Phylogeny and In Silico Structure Analysis of Major Capsid Protein (L1) Human Papillomavirus 45 from Indonesian Isolates
Mutation
3 23451059 Sequence variation analysis of HPV-18 isolates in southwest China
Mutation
4 25111286 Prevalence of HPV and variation of HPV 16/HPV 18 E6/E7 genes in cervical cancer in women in South West China
Mutation
5 28036379 Different Association of Human Papillomavirus 16 Variants with Early and Late Presentation of Cervical Cancer
Mutation
6 29783960 Performance of OncoE6 cervical test with collection methods enabling self-sampling
Mutation
7 30981880 Human papillomavirus type 16 E6 and E7 gene variations associated with cervical cancer in a Han Chinese population
Mutation
8 32308546 Association of Human Papillomavirus Type 16 Long Control Region Variations with Cervical Cancer in a Han Chinese Population
Mutation
9 35193568 HPV16 E6 gene polymorphisms and the functions of the mutation site in cervical cancer among Uygur ethnic and Han nationality women in Xinjiang, China
Mutation
10 36680149 Genetic Variability in the E6, E7, and L1 Genes of Human Papillomavirus Types 16 and 18 among Women in Saudi Arabia
Mutation
11 38520797 Distribution of human papillomavirus among Vietnamese women with cervical cancer and unusual genetic variability of HPV16
Mutation
12 38158635 Decoding the Genetic and Structural Features of HPV16 E5 Oncogene in Cervical Cancer Isolates from Pakistan: A Pilot Study
Mutation
13 22524831 Whole genome analysis of human papillomavirus type 16 multiple infection in cervical cancer patients
Mutation
14 30008422 The association of human papillomavirus type 16 E2 variations with cervical cancer in a Han Chinese population
Mutation
15 33324377 High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer
Mutation
16 31341418 Human Papillomavirus Type 16 E1 Mutations Associated with Cervical Cancer in a Han Chinese Population
Mutation
17 39154329 HPV-16 E6 mutation and viral integration related host DNA methylation implicate the development and progression of cervical cancer
Mutation
18 12820481 Co-mutation of HPV16 E6 and E7 genes in Thai squamous cervical carcinomas
Mutation
19 33909391 Sequence variation analysis of the E1 and E2 genes of human papillomavirus type 16 in cervical lesions in women from the south of Poland
Mutation
20 24601042 Research on sequence variations analysis of HPV-16 type in Southwestern China
Mutation
21 28441787 Codon Usage Optimization and Construction of Plasmid Encoding Iranian Human Papillomavirus Type 16 E7 Oncogene for Lactococcus Lactis Subsp. Cremoris MG1363
Mutation
22 10783118 Absence of antibody against human papillomavirus type 16 E6 and E7 in patients with cervical cancer is independent of sequence variations
Mutation
23 1655963 Sequencing data on the long control region of human papillomavirus type 16
Mutation
24 9264576 Major sequence variants in E7 gene of human papillomavirus type 16 from cervical cancerous and noncancerous lesions of Korean women
Mutation
25 20870281 Distribution of human papillomavirus 58 and 52 E6/E7 variants in cervical neoplasia in Chinese women
Mutation
26 40192871 Genetic analysis of HPV-16 L1 gene mutations and computational screening of therapeutic inhibitors for cervical cancer treatment
Mutation
27 28794033 Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants
Mutation
28 32448303 Fifteen new nucleotide substitutions in variants of human papillomavirus 18 in Korea : Korean HPV18 variants and clinical manifestation
Mutation
29 18512138 A non-radioactive PCR-SSCP analysis allows to distinguish between HPV 16 European and Asian-American variants in squamous cell carcinomas of the uterine cervix in Colombia
Mutation
30 22571619 Human papillomavirus type 58: the unique role in cervical cancers in East Asia
Mutation
31 24368255 Genetic variability of HPV-58 E6 and E7 genes in Southwest China
Mutation
32 33155930 Human Papillomavirus E7 Oncoprotein Promotes Proliferation and Migration through the Transcription Factor E2F1 in Cervical Cancer Cells
Mutation
33 12189229 Association of human papillomavirus type 58 variant with the risk of cervical cancer
Mutation
34 30676312 Oncogenicitiy Comparison of Human Papillomavirus Type 52 E6 Variants
Mutation
35 23977318 Evolution and taxonomic classification of alphapapillomavirus 7 complete genomes: HPV18, HPV39, HPV45, HPV59, HPV68 and HPV70
Mutation
36 36950084 Polymorphism of E6 and E7 Genes in Human Papillomavirus Types 31 and 33 in Northeast China
Mutation
37 10917543 Uneven distribution of HPV 16 E6 prototype and variant (L83V) oncoprotein in cervical neoplastic lesions
Mutation
38 9485042 Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype
Mutation
39 29142126 Human Papillomavirus Replication Regulation by Acetylation of a Conserved Lysine in the E2 Protein
Mutation
40 38970084 Genetic variability of human papillomavirus type 18 based on E6, E7 and L1 genes in central China
Mutation
41 10880765 Enhanced oncogenicity of human papillomavirus type 16 (HPV16) variants in Japanese population
Mutation
42 16099904 Differential splicing of E6 within human papillomavirus type 18 variants and functional consequences
Mutation
43 15670304 Polymorphism in the E6 gene of human papillomavirus type 16 in the cervical tissues of Korean women
Mutation
44 15491758 E2 sequence variations of HPV 16 among patients with cervical neoplasia seen in the Indian subcontinent
Mutation
45 34209097 Mutation Profiles, Glycosylation Site Distribution and Codon Usage Bias of Human Papillomavirus Type 16
Mutation
46 1321216 Geographical dependence of sequence variation in the E7 gene of human papillomavirus type 16
Mutation
47 12195358 Human papillomavirus type 16 intratypic variant infection and risk for cervical neoplasia in southern China
Mutation
48 27030265 The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC
Mutation
49 27693214 Identification of the impact on T- and B- cell epitopes of human papillomavirus type-16 E6 and E7 variant in Southwest China
Mutation
50 33573298 Modeling and Molecular Dynamics of the 3D Structure of the HPV16 E7 Protein and Its Variants
Mutation
51 19015633 A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells
Mutation
52 30930693 Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in Xinjiang, China
Mutation
53 29893470 CIP2A facilitates the G1/S cell cycle transition via B-Myb in human papillomavirus 16 oncoprotein E6-expressing cells
Mutation
54 18986660 Human papillomavirus 16 E6 variants differ in their dysregulation of human keratinocyte differentiation and apoptosis
Mutation
55 20383192 The immortalizing and transforming ability of two common human papillomavirus 16 E6 variants with different prevalences in cervical cancer
Mutation
56 24150786 Functional effects of sequence variations in the E6 and E2 genes of human papillomavirus 16 European and Asian variants
Mutation
57 31426742 In silico prediction of structural changes in human papillomavirus type 16 (HPV16) E6 oncoprotein and its variants
Mutation
58 33374731 High Risk alpha-HPV E6 Impairs Translesion Synthesis by Blocking POLeta Induction
Mutation
59 38048896 The E6 gene polymorphism of Human papillomavirus 16 in relation to the risk of cervical cancer in Tunisian women
Mutation
60 24456830 Replication interference between human papillomavirus types 16 and 18 mediated by heterologous E1 helicases
Mutation
61 2543768 A novel deletion within the upstream regulatory region of episomal human papillomavirus type 16
Mutation
62 22558401 Human papillomavirus (HPV) 16 E6 variants in tonsillar cancer in comparison to those in cervical cancer in Stockholm, Sweden
Mutation
63 31552532 Mutational landscape and intra-host diversity of human papillomavirus type 16 long control region and E6 variants in cervical samples
Mutation
64 27610192 Molecular analysis of human Papillomavirus detected among women positive for cervical lesions by visual inspection with acetic acid/Lugol's iodine (VIA/VILI) in Libreville, Gabon
Mutation
65 24236186 Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing
Mutation
66 25889023 Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico
Mutation
67 33660963 Distribution of human papillomavirus genotypes in women with high-grade cervical intraepithelial lesions and cervical carcinoma and analysis of human papillomavirus-16 genomic variants
Mutation
68 37759219 Genetic variation of E6 and E7 genes of human papillomavirus type 16 from central China
Mutation
69 40243019 Patterns of Co-infection of HPV52 With Other HPV Genotypes and Their Risks of Cervical Precancer and Carcinoma
Mutation
70 27977741 Analysis of Sequence Variation and Risk Association of Human Papillomavirus 52 Variants Circulating in Korea
Mutation
71 36557745 Characterization of Human Papillomavirus 16 from Kinshasa (Democratic Republic of the Congo)-Implications for Pathogenicity and Vaccine Effectiveness
Mutation
72 30081093 HPV16 E2 variants correlated with radiotherapy treatment and biological significance in cervical cell carcinoma
Mutation
73 21593270 Human papillomavirus type 16 variant analysis of E6, E7, and L1 [corrected] genes and long control region in [corrected] cervical carcinomas in patients in northeast China
Mutation
74 34217247 Association of cervical carcinogenesis risk with HPV16 E6 and E7 variants in the Taizhou area, China
Mutation
75 34203053 E6/E7 Variants of Human Papillomavirus 16 Associated with Cervical Carcinoma in Women in Southern Mexico
Mutation
76 10567656 Human papillomavirus type 16 E6 variants in cervical carcinoma: relationship to host genetic factors and clinical parameters
Mutation
77 15363193 [Analysis of human papillomavirus 16 E6 oncogene mutation in Xinjiang Uygur women with cervical carcinoma]
Mutation
78 15929080 Interaction of host and viral risk factors for development of cervical carcinoma in situ
Mutation
79 21552834 Polymorphism of the hpv-16 e6 gene of cervical-carcinoma
Mutation
80 23762404 Differential expression of HPV16 L2 gene in cervical cancers harboring episomal HPV16 genomes: influence of synonymous and non-coding region variations
Mutation
81 23203106 Genomic polymorphism of human papillomavirus type 52 in women from Northeast China
Mutation
82 37179021 Diversity of cervicovaginal human papillomavirus (HPV) genotypes and naturally occurring E6/E7 DNA polymorphisms of HPV-16 in Ghana
Mutation
83 28270859 Genetic variability in E6, E7 and L1 genes of Human Papillomavirus 62 and its prevalence in Mexico
Mutation
84 11870518 Variants of the long control region and the E6 oncogene in European human papillomavirus type 16 isolates: implications for cervical disease
Mutation
85 11745467 Human papillomavirus 16 E6 polymorphisms in cervical lesions from different European populations and their correlation with human leukocyte antigen class II haplotypes
Mutation
86 21051983 Distribution of human papillomavirus 16 E6/E7 variants in cervical cancer and intraepithelial neoplasia in Chinese women
Mutation
87 31289133 The HPV16 Genome Is Stable in Women Who Progress to In Situ or Invasive Cervical Cancer: A Prospective Population-Based Study
Mutation
88 26192265 Distribution of human papilloma virus type 16 E6/E7 gene mutation in cervical precancer or cancer: A case control study in Guizhou Province, China
Mutation
89 25143263 Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients
Mutation
90 28959092 Naturally occurring capsid protein variants L1 of human papillomavirus genotype 16 in Morocco
Mutation
91 30995759 Whole-Genome Analysis of Human Papillomavirus Type 16 Prevalent in Japanese Women with or without Cervical Lesions
Mutation
92 19256739 Distribution of HPV-16 intratypic variants among women with cervical intraepithelial neoplasia and invasive cervical cancer in Mongolia
Mutation
93 10389753 Uniform distribution of HPV 16 E6 and E7 variants in patients with normal histology, cervical intra-epithelial neoplasia and cervical cancer
Mutation
94 24099556 Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China
Mutation
95 25991921 Genetic variability in E6 and E7 oncogenes of human papillomavirus Type 16 from Congolese cervical cancer isolates
Mutation
96 38745409 Distribution of HPV types among women with HPV-related diseases and exploration of lineages and variants of HPV 52 and 58 among HPV-infected patients in China: A systematic literature review
Mutation
97 20423887 [Human papillomavirus type 16 variant analysis of upstream regulatory region and E6, E7 oncogene from cervical cancer patients in Beijing]
Mutation
98 31493439 Distribution of HPV 16 E6 gene variants in screening women and its associations with cervical lesions progression
Mutation
99 28767682 Genetic variability and functional implication of the long control region in HPV-16 variants in Southwest China
Mutation
100 28988982 Phylogenetic analysis of Human papillomavirus 16 variants isolated from Indian Breast cancer patients showed difference in genetic diversity with that of cervical cancer isolates
Mutation
101 30583341 Phylogeny and Classification of Human Papillomavirus (HPV)16 and HPV18 Variants Based on E6 and L1 genes in Tunisian Women with Cervical Lesions
Mutation
102 37376692 Genetic Variability in the E6/E7 Region of Human Papillomavirus 16 in Women from Ecuador
Mutation
103 22659102 Variations of human papillomavirus type 58 E6, E7, L1 genes and long control region in strains from women with cervical lesions in Liaoning province, China
Mutation
104 28141822 E6 and E7 Gene Polymorphisms in Human Papillomavirus Types-58 and 33 Identified in Southwest China
Mutation
105 22622951 Variant lineages of human papillomavirus type 18 in Northeast China populations characterized by sequence analysis of E6, E7, and L1 regions
Mutation
106 21436703 Genetic diversity of HPV-16 E6, E7, and L1 genes in women with cervical lesions in Liaoning Province, China
Mutation
107 27654117 HPV16 variants distribution in invasive cancers of the cervix, vulva, vagina, penis, and anus
Mutation
108 27801430 HPV16 E6 polymorphism and physical state of viral genome in relation to the risk of cervical cancer in women from the south of Poland
Mutation
109 30161236 Differences in the viral genome between HPV-positive cervical and oropharyngeal cancer
Mutation
110 18199779 Human papillomavirus type 16 variant analysis of E6, E7, and L1 genes and long control region in biopsy samples from cervical cancer patients in north India
Mutation
111 29945151 Genetic Variability in E6 and E7 Oncogenes from Human Papillomavirus Type 58 in Mexican Women
Mutation
112 38241590 The difference of transcriptome of HPV-infected patients contributes more to the occurrence of cervical cancer than the mutations of E6 and E7 genes in HPV16
Mutation
113 23946477 Molecular and evolutionary analysis of HPV16 E6 and E7 genes in Greek women
Mutation
114 22131113 Prevalence of HPV 16 genomic variant carrying a 63 bp duplicated sequence within the E1 gene in Slovenian women
Mutation
115 16333213 [Investigation of human papillomavirus, its types and variants]
Mutation
116 23881083 Nucleotide polymorphisms of the human papillomavirus 16 E1 gene
Mutation
117 23343096 Association of human papillomavirus type 16 long control region mutation and cervical cancer
Mutation
118 28325903 Whole-Genome Analysis of Human Papillomavirus Types 16, 18, and 58 Isolated from Cervical Precancer and Cancer Samples in Chinese Women
Mutation
119 15297193 Human papillomavirus type 16 E6, E7, and L1 variants in cervical cancer in Indonesia, Suriname, and The Netherlands
Mutation
120 16603519 Analysis of mutations in the E6/E7 oncogenes and L1 gene of human papillomavirus 16 cervical cancer isolates from China
Mutation
121 19358280 Molecular variants of HPV-16 associated with cervical cancer in Indian population
Mutation
122 15572004 The prevalence of HPV-18 and variants of E6 gene isolated from cervical cancer patients in Taiwan
Mutation
123 16012730 Sequence variation and the transcriptional activity of the upstream regulatory region in human papillomavirus 16 E7 variants in cervical cancer of Korean women
Mutation
124 20104743 [Gene characterization of E6 and E7 gene of human papillomavirus of 15 cervical cancer in Beijing]
Mutation
125 28819444 Association of HLA-DRB1, HLA-DQB1 Polymorphisms with HPV 16 E6 Variants among Young Cervical Cancer Patients in China
Mutation
126 12691704 Association between human papillomavirus 16 E6 variants and human leukocyte antigen class I polymorphism in cervical cancer of Swedish women
Mutation
127 12918070 Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese women with cervical cancer
Mutation
128 19699050 Human papillomavirus type 16 E6 gene variations in Chinese population
Mutation
129 22574185 Whole genome sequencing and evolutionary analysis of human papillomavirus type 16 in central China
Mutation
130 23953248 Analysis of mutations in the E6 oncogene of human papillomavirus 16 in cervical cancer isolates from Moroccan women
Mutation
131 24610458 HPV16 E6 variants: frequency, association with HPV types and in silico analysis of the identified novel variants
Mutation
132 29364907 HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression
Integration
133 24390348 Landscape of genomic alterations in cervical carcinomas
Integration
134 24201445 Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
Integration
135 25581428 Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
Integration
136 26660085 Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer
Integration
137 23740984 Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq
Integration
138 18922896 Characterization of naturally occurring HPV16 integration sites isolated from cervical keratinocytes under noncompetitive conditions
Integration
139 30679491 TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration
Integration
140 24418928 Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing
Integration
141 16682952 MYC activation associated with the integration of HPV DNA at the MYC locus in genital tumors
Integration
142 26735580 Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology
Integration
143 27759101 Genome-wide profiling of the human papillomavirus DNA integration in cervical intraepithelial neoplasia and normal cervical epithelium by HPV capture technology
Integration
144 25485619 A comprehensive transcriptional portrait of human cancer cell lines
Integration
145 32714374 Accurate Detection of HPV Integration Sites in Cervical Cancer Samples Using the Nanopore MinION Sequencer Without Error Correction
Integration
146 33191407 Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
Integration
147 30567904 Comprehensive genomic variation profiling of cervical intraepithelial neoplasia and cervical cancer identifies potential targets for cervical cancer early warning
Integration
148 32025001 The landscape of viral associations in human cancers
Integration
149 29487700 Increased high mobility group A 2 expression promotes transition of cervical intraepithelial neoplasm into cervical cancer
Integration
150 31014281 HPV DNA integration site as proof of the origin of ovarian metastasis from endocervical adenocarcinoma: three case reports
Integration
151 30264502 Nuclear factor I X is a recurrent target for HPV16 insertions in anal carcinomas
Integration
152 30016933 HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data
Integration
153 30728408 Genome-wide profiling of human papillomavirus DNA integration in liquid-based cytology specimens from a Gabonese female population using HPV capture technology
Integration
154 30552977 Characterization of HPV integration, viral gene expression and E6E7 alternative transcripts by RNA-Seq: A descriptive study in invasive cervical cancer
Integration
155 33023834 HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer
Integration
156 33785400 Integrated analysis of virus and host transcriptomes in cervical cancer in Asian and Western populations
Integration
157 38932267 HPV, HBV, and HIV-1 Viral Integration Site Mapping: A Streamlined Workflow from NGS to Genomic Insights of Carcinogenesis
Integration
158 35968887 Genome-wide virus-integration analysis reveals a common insertional mechanism of HPV, HBV and EBV
Integration
159 23824673 Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas
Mutation


Integration
160 32631904 The D2 and D3 Sublineages of Human Papilloma Virus 16-Positive Cervical Cancer in Guatemala Differ in Integration Rate and Age of Diagnosis
Mutation


Integration
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.