Overview of HPV associated (Mutation)

ID Literature Title Group
1 22558401 Human papillomavirus (HPV) 16 E6 variants in tonsillar cancer in comparison to those in cervical cancer in Stockholm, Sweden
Mutation
2 31552532 Mutational landscape and intra-host diversity of human papillomavirus type 16 long control region and E6 variants in cervical samples
Mutation
3 27610192 Molecular analysis of human Papillomavirus detected among women positive for cervical lesions by visual inspection with acetic acid/Lugol's iodine (VIA/VILI) in Libreville, Gabon
Mutation
4 24236186 Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing
Mutation
5 25889023 Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico
Mutation
6 33660963 Distribution of human papillomavirus genotypes in women with high-grade cervical intraepithelial lesions and cervical carcinoma and analysis of human papillomavirus-16 genomic variants
Mutation
7 37759219 Genetic variation of E6 and E7 genes of human papillomavirus type 16 from central China
Mutation
8 40243019 Patterns of Co-infection of HPV52 With Other HPV Genotypes and Their Risks of Cervical Precancer and Carcinoma
Mutation
9 27977741 Analysis of Sequence Variation and Risk Association of Human Papillomavirus 52 Variants Circulating in Korea
Mutation
10 36557745 Characterization of Human Papillomavirus 16 from Kinshasa (Democratic Republic of the Congo)-Implications for Pathogenicity and Vaccine Effectiveness
Mutation
11 32677948 Genetic variability, phylogeny and functional implication of the long control region in human papillomavirus type 16, 18 and 58 in Chengdu, China
Mutation
12 34217247 Association of cervical carcinogenesis risk with HPV16 E6 and E7 variants in the Taizhou area, China
Mutation
13 31511025 E6 and E7 gene polymorphisms in human papillomavirus Type-6 identified in Southwest China
Mutation
14 31832087 Phylogeny and polymorphism in the E6 and E7 of human papillomavirus: alpha-9 (HPV16, 31, 33, 52, 58), alpha-5 (HPV51), alpha-6 (HPV53, 66), alpha-7 (HPV18, 39, 59, 68) and alpha-10 (HPV6, 44) in women from Shanghai
Mutation
15 23203106 Genomic polymorphism of human papillomavirus type 52 in women from Northeast China
Mutation
16 37179021 Diversity of cervicovaginal human papillomavirus (HPV) genotypes and naturally occurring E6/E7 DNA polymorphisms of HPV-16 in Ghana
Mutation
17 28270859 Genetic variability in E6, E7 and L1 genes of Human Papillomavirus 62 and its prevalence in Mexico
Mutation
18 11870518 Variants of the long control region and the E6 oncogene in European human papillomavirus type 16 isolates: implications for cervical disease
Mutation
19 11745467 Human papillomavirus 16 E6 polymorphisms in cervical lesions from different European populations and their correlation with human leukocyte antigen class II haplotypes
Mutation
20 21051983 Distribution of human papillomavirus 16 E6/E7 variants in cervical cancer and intraepithelial neoplasia in Chinese women
Mutation
21 31289133 The HPV16 Genome Is Stable in Women Who Progress to In Situ or Invasive Cervical Cancer: A Prospective Population-Based Study
Mutation
22 26192265 Distribution of human papilloma virus type 16 E6/E7 gene mutation in cervical precancer or cancer: A case control study in Guizhou Province, China
Mutation
23 25143263 Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients
Mutation
24 30995759 Whole-Genome Analysis of Human Papillomavirus Type 16 Prevalent in Japanese Women with or without Cervical Lesions
Mutation
25 19256739 Distribution of HPV-16 intratypic variants among women with cervical intraepithelial neoplasia and invasive cervical cancer in Mongolia
Mutation
26 10389753 Uniform distribution of HPV 16 E6 and E7 variants in patients with normal histology, cervical intra-epithelial neoplasia and cervical cancer
Mutation
27 24099556 Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China
Mutation
28 38745409 Distribution of HPV types among women with HPV-related diseases and exploration of lineages and variants of HPV 52 and 58 among HPV-infected patients in China: A systematic literature review
Mutation
29 31493439 Distribution of HPV 16 E6 gene variants in screening women and its associations with cervical lesions progression
Mutation
30 19508521 Extensive anal condylomatosis: prognosis in relation to viral and host factors
Mutation
31 28988982 Phylogenetic analysis of Human papillomavirus 16 variants isolated from Indian Breast cancer patients showed difference in genetic diversity with that of cervical cancer isolates
Mutation
32 30583341 Phylogeny and Classification of Human Papillomavirus (HPV)16 and HPV18 Variants Based on E6 and L1 genes in Tunisian Women with Cervical Lesions
Mutation
33 37376692 Genetic Variability in the E6/E7 Region of Human Papillomavirus 16 in Women from Ecuador
Mutation
34 22659102 Variations of human papillomavirus type 58 E6, E7, L1 genes and long control region in strains from women with cervical lesions in Liaoning province, China
Mutation
35 28141822 E6 and E7 Gene Polymorphisms in Human Papillomavirus Types-58 and 33 Identified in Southwest China
Mutation
36 22622951 Variant lineages of human papillomavirus type 18 in Northeast China populations characterized by sequence analysis of E6, E7, and L1 regions
Mutation
37 21436703 Genetic diversity of HPV-16 E6, E7, and L1 genes in women with cervical lesions in Liaoning Province, China
Mutation
38 27717385 L1 and L2 gene polymorphisms in HPV-58 and HPV-33: implications for vaccine design and diagnosis
Mutation
39 27654117 HPV16 variants distribution in invasive cancers of the cervix, vulva, vagina, penis, and anus
Mutation
40 27801430 HPV16 E6 polymorphism and physical state of viral genome in relation to the risk of cervical cancer in women from the south of Poland
Mutation
41 30161236 Differences in the viral genome between HPV-positive cervical and oropharyngeal cancer
Mutation
42 12189229 Association of human papillomavirus type 58 variant with the risk of cervical cancer
Mutation
43 29945151 Genetic Variability in E6 and E7 Oncogenes from Human Papillomavirus Type 58 in Mexican Women
Mutation
44 12195358 Human papillomavirus type 16 intratypic variant infection and risk for cervical neoplasia in southern China
Mutation
45 9485042 Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype
Mutation
46 38241590 The difference of transcriptome of HPV-infected patients contributes more to the occurrence of cervical cancer than the mutations of E6 and E7 genes in HPV16
Mutation
47 23946477 Molecular and evolutionary analysis of HPV16 E6 and E7 genes in Greek women
Mutation
48 22131113 Prevalence of HPV 16 genomic variant carrying a 63 bp duplicated sequence within the E1 gene in Slovenian women
Mutation
49 16333213 [Investigation of human papillomavirus, its types and variants]
Mutation
50 23881083 Nucleotide polymorphisms of the human papillomavirus 16 E1 gene
Mutation
51 28325903 Whole-Genome Analysis of Human Papillomavirus Types 16, 18, and 58 Isolated from Cervical Precancer and Cancer Samples in Chinese Women
Mutation
52 39861045 A Conserved Di-Lysine Motif in the E2 Transactivation Domain Regulates MmuPV1 Replication and Disease Progression
Mutation
53 28426749 Molecular characterization, tissue tropism, and genetic variability of the novel Mupapillomavirus type HPV204 and phylogenetically related types HPV1 and HPV63
Mutation
54 32503989 Rational design of a multi-valent human papillomavirus vaccine by capsomere-hybrid co-assembly of virus-like particles
Mutation
55 10639310 HPV11 mutant virus-like particles elicit immune responses that neutralize virus and delineate a novel neutralizing domain
Mutation
56 33941222 The genetic variability, phylogeny and functional significance of E6, E7 and LCR in human papillomavirus type 52 isolates in Sichuan, China
Mutation
57 23588734 E6 and E7 variants of human papillomavirus-16 and -52 in Japan, the Philippines, and Vietnam
Mutation
58 30911096 Characterization of an HPV33 natural variant with enhanced transcriptional activity suggests a role for C/EBPbeta in the regulation of the viral early promoter
Mutation
59 11336560 Induction of type-specific neutralizing antibodies by capsomeres of human papillomavirus type 33
Mutation
60 30842331 Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication
Mutation
61 32350070 Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication
Mutation
62 32493825 Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance
Mutation
63 20572344 [The enhancement of DNA binding ability of a mutated E2 (A338V) protein of HPV-2]
Mutation
64 25227848 A novel mutant of human papillomavirus type 18 E6E7 fusion gene and its transforming activity
Mutation
65 29630659 STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle
Mutation
66 30322153 HPV-18 E6 Oncoprotein and Its Spliced Isoform E6*I Regulate the Wnt/beta-Catenin Cell Signaling Pathway through the TCF-4 Transcriptional Factor
Mutation
67 17048111 New HPV-16 European and non-European variants in Central Brazil
Mutation
68 25735347 Mutation detection of E6 and LCR genes from HPV 16 associated with carcinogenesis
Mutation
69 19214230 Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes
Mutation
70 20668481 Efficient delivery of DNA vaccines using human papillomavirus pseudovirions
Mutation
71 24928042 The nuclear retention signal of HPV16 L2 protein is essential for incoming viral genome to transverse the trans-Golgi network
Mutation
72 38196081 Whole-genome analysis and evolutionary characterization of cervical and oral human papillomavirus 16
Mutation
73 21811610 Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16
Mutation
74 24918586 Roles for human papillomavirus type 16 l1 cysteine residues 161, 229, and 379 in genome encapsidation and capsid stability
Mutation
75 25096873 Maturation of the human papillomavirus 16 capsid
Mutation
76 26732286 Enhanced expression of soluble human papillomavirus L1 through coexpression of molecular chaperonin in Escherichia coli
Mutation
77 28968823 Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization
Mutation
78 32304786 HPV16 L1 diversity and its potential impact on the vaccination-induced immunity
Mutation
79 32435064 The possible regions to design Human Papilloma Viruses vaccine in Iranian L1 protein
Mutation
80 10861636 Analysis of relative binding affinity of E7-pRB of human papillomavirus 16 clinical variants using the yeast two-hybrid system
Mutation
81 11543887 Determination of the binding affinity of different human papillomavirus E7 proteins for the tumour suppressor pRb by a plate-binding assay
Mutation
82 12196821 [Modification of HPV type 16 E6 and E7 genes, and analysis of stability and immunogenicity of the modified proteins]
Mutation
83 12239337 Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells
Mutation
84 16800784 The human papillomavirus type 16 E7 protein binds human interferon regulatory factor-9 via a novel PEST domain required for transformation
Mutation
85 27829177 A naturally occurring variant of HPV-16 E7 exerts increased transforming activity through acquisition of an additional phospho-acceptor site
Mutation
86 31915229 Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene Transcription
Mutation
87 35348640 HPVMD-C: a disease-based mutation database of human papillomavirus in China
Mutation
88 10400710 The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300
Mutation
89 12551970 Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways
Mutation
90 16519914 HPV16 E6 natural variants exhibit different activities in functional assays relevant to the carcinogenic potential of E6
Mutation
91 17452980 hAda3 regulates p14ARF-induced p53 acetylation and senescence
Mutation
92 17854024 Activities of human papillomavirus 16 E6 natural variants in human keratinocytes
Mutation
93 26318249 The human papillomavirus 16 European-T350G E6 variant can immortalize but not transform keratinocytes in the absence of E7
Mutation
94 27806689 Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology
Mutation
95 28497579 Modulation of basal cell fate during productive and transforming HPV-16 infection is mediated by progressive E6-driven depletion of Notch
Mutation
96 8627680 Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions
Mutation
97 9733858 A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro
Mutation
98 12565157 DNA replicative functions of highly-expressed, codon-optimized human papillomavirus proteins E1 and E2
Mutation
99 18619639 Modification of papillomavirus E2 proteins by the small ubiquitin-like modifier family members (SUMOs)
Mutation
100 9223484 Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.