Gene Information
|
Gene Name
|
ADRA1A |
|
Gene ID
|
148
|
|
Gene Full Name
|
adrenoceptor alpha 1A |
|
Gene Alias
|
ADRA1C|ADRA1L1|ALPHA1AAR |
|
Transcripts
|
ENSG00000120907
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;Nucleoplasm, Vesicles; 
|
|
Membrane Info
|
FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins |
|
Uniport_ID
|
P35348
|
|
HGNC ID
|
HGNC:277
|
|
OMIM ID
|
104221 |
|
Summary
|
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008] |
Target gene [ADRA1A] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1001338 |
chr8 |
171 |
247 |
413 |
831 |
View |
| 1008866 |
chr8 |
13 |
5 |
1 |
19 |
View |
| 1017439 |
chr8 |
0 |
1 |
0 |
1 |
View |
| 1020106 |
chr8 |
35 |
0 |
0 |
35 |
View |
| 1024347 |
chr8 |
1 |
2 |
0 |
3 |
View |
Target gene [ADRA1A] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
E GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE100400 - ADRA1A expression across samples
|
Volcano Plot
|
Bar Plot
|
> Dataset: GSE94660 - ADRA1A expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
HBV Target gene Detail Information
