Gene Information
|
Gene Name
|
APOL1 |
|
Gene ID
|
8542
|
|
Gene Full Name
|
apolipoprotein L1 |
|
Gene Alias
|
APO-L|APOL|APOL-I|FSGS4 |
|
Transcripts
|
ENSG00000100342
|
|
Virus
|
XMRV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Secreted to blood;
|
|
Membrane Info
|
Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters |
|
Uniport_ID
|
O14791
|
|
HGNC ID
|
HGNC:618
|
|
OMIM ID
|
603743 |
|
Summary
|
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] |
Target gene [APOL1] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 8000044 |
chr22 |
1091 |
1956 |
1275 |
4322 |
View |
|
|