XMRV Target gene Detail Information

> APOL1 Gene Search Result


Gene Information
Gene Name APOL1
Gene ID 8542
Gene Full Name apolipoprotein L1
Gene Alias APO-L|APOL|APOL-I|FSGS4
Transcripts ENSG00000100342
Virus XMRV
Gene Type protein-coding
HPA Location Info Secreted to blood;
Membrane Info Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters
Uniport_ID O14791
HGNC ID HGNC:618
OMIM ID 603743
Summary This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Target gene [APOL1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
8000044 chr22 1091 1956 1275 4322 View