XMRV Target gene Detail Information

> APPBP2 Gene Search Result


Gene Information
Gene Name APPBP2
Gene ID 10513
Gene Full Name amyloid beta precursor protein binding protein 2
Gene Alias APP-BP2|HS.84084|PAT1
Transcripts ENSG00000062725
Virus XMRV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID Q92624
HGNC ID HGNC:622
OMIM ID 605324
Summary The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Target gene [APPBP2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
8000014 chr17 11 22 23 56 View