Gene Name	CAV2
Gene ID	858
Gene Full Name	caveolin 2
Gene Alias	CAV
Transcripts	ENSG00000105971
Virus	XMRV
Gene Type	protein-coding
HPA Location Info	Vesicles;
Membrane Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P51636
HGNC ID	HGNC:1528
OMIM ID	601048
Summary	The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
8000051	chr7	2585	1864	1027	5476	View