HBV Target gene Detail Information

> CHRM3 Gene Search Result


Gene Information
Gene Name CHRM3
Gene ID 1131
Gene Full Name cholinergic receptor muscarinic 3
Gene Alias EGBRS|HM3|PBS|m3AChR
Transcripts ENSG00000133019
Virus HBV
Gene Type protein-coding
HPA Location Info Plasma membrane;
Membrane Info Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins
Uniport_ID P20309
HGNC ID HGNC:1952
OMIM ID 118494
Summary The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Target gene [CHRM3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002582 chr1 104 84 54 242 View
1008952 chr1 18 0 0 18 View
1010760 chr1 0 11 0 11 View
1011106 chr1 0 10 0 10 View
1011861 chr1 0 6 2 8 View
1011862 chr1 0 8 0 8 View
1012841 chr1 0 5 1 6 View
1013441 chr1 0 5 0 5 View
1013442 chr1 0 5 0 5 View
1014117 chr1 0 4 0 4 View
1014118 chr1 0 4 0 4 View
1015825 chr1 0 2 0 2 View
1016433 chr1 0 0 1 1 View
1017092 chr1 0 1 0 1 View
1019231 chr1 0 0 0 0 View
1019232 chr1 0 0 0 0 View
1019233 chr1 0 0 0 0 View
1019234 chr1 0 0 0 0 View
1019235 chr1 0 0 0 0 View
1019236 chr1 0 0 0 0 View
1041780 chr1 7 0 1 8 View
1041781 chr1 34 3 1 38 View

Target gene [CHRM3] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - CHRM3 expression across samples

Volcano Plot

Bar Plot