Gene Name	CPAP
Gene ID	55835
Gene Full Name	centrosome assembly and centriole elongation protein
Gene Alias	BM032|CENP-J|CENPJ|LAP|LIP1|MCPH6|SASS4|SCKL4|Sas-4
Transcripts	ENSG00000151849
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Centrosome;Acrosome;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID	Q9HC77
HGNC ID	HGNC:17272
OMIM ID	609279
Summary	This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5006972	chr13	32	0	1	33	View