HBV Target gene Detail Information

> DUX4 Gene Search Result


Gene Information
Gene Name DUX4
Gene ID 100288687
Gene Full Name double homeobox 4
Gene Alias DUX4L
Transcripts ENSG00000260596
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nucleoli;Golgi apparatus, Cytosol;
Membrane Info Disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters
Uniport_ID Q9UBX2
HGNC ID HGNC:50800
OMIM ID 606009
Summary This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Target gene [DUX4] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1020260 chr18 188 197 103 488 View
1024449 chr10 1 0 0 1 View

Target gene [DUX4] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
GSE131257 ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE100400 - DUX4 peak across samples

Peak Plot