Gene Information
|
Gene Name
|
DYNLL1 |
|
Gene ID
|
8655
|
|
Gene Full Name
|
dynein light chain LC8-type 1 |
|
Gene Alias
|
DLC1|DLC8|DNCL1|DNCLC1|LC8|LC8a|PIN|hdlc1 |
|
Transcripts
|
ENSG00000088986
|
|
Virus
|
RABV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
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Nucleoplasm, Cytosol, Mid piece, Principal piece; 
|
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Membrane Info
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Cancer-related genes, Plasma proteins, Predicted intracellular proteins |
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Uniport_ID
|
P63167
|
|
HGNC ID
|
HGNC:15476
|
|
OMIM ID
|
601562 |
|
Summary
|
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |
Target gene [DYNLL1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
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RABV Target gene Detail Information
