XMRV Target gene Detail Information

> EDN2 Gene Search Result


Gene Information
Gene Name EDN2
Gene ID 1907
Gene Full Name endothelin 2
Gene Alias ET-2|ET2|PPET2
Transcripts ENSG00000127129
Virus XMRV
Gene Type protein-coding
HPA Location Info Cytosol;Secreted to blood;
Membrane Info Predicted secreted proteins
Uniport_ID P20800
HGNC ID HGNC:3177
OMIM ID 131241
Summary This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Target gene [EDN2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
8000057 chr1 2407 616 127 3150 View