HSV2 Target gene Detail Information

> EEF1D Gene Search Result


Gene Information
Gene Name EEF1D
Gene ID 1936
Gene Full Name eukaryotic translation elongation factor 1 delta
Gene Alias EF-1D|EF1D|FP1047|NEDTCHAL
Transcripts ENSG00000104529
Virus HSV2
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nucleoli fibrillar center;
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P29692
HGNC ID HGNC:3211
OMIM ID 130592
Summary This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010]
Target gene [EEF1D] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 29899106 S18A
UL13
UL13
Cell line
T
View
2 29899106 S18D
UL13
UL13
Cell line
T
View
3 29899106 S91A
UL13
UL13
Cell line
T
View
4 29899106 K176M
UL13
UL13
Cell line
T
View

Target gene [EEF1D] related to Omics data
Data ID Experiment type Sample number Platform
GSE241702 RNA-seq 8 Illumina HiSeq 4000 (Homo sapiens)
GSE229390 RNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)