Gene Information
|
Gene Name
|
EEF1D |
|
Gene ID
|
1936
|
|
Gene Full Name
|
eukaryotic translation elongation factor 1 delta |
|
Gene Alias
|
EF-1D|EF1D|FP1047|NEDTCHAL |
|
Transcripts
|
ENSG00000104529
|
|
Virus
|
HSV2 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nucleoli fibrillar center;
|
|
Membrane Info
|
Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
P29692
|
|
HGNC ID
|
HGNC:3211
|
|
OMIM ID
|
130592 |
|
Summary
|
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010] |
Target gene [EEF1D] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [EEF1D] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE241702
|
RNA-seq |
8 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE229390
|
RNA-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
|