Gene Information
|
Gene Name
|
GABRG3 |
|
Gene ID
|
2567
|
|
Gene Full Name
|
gamma-aminobutyric acid type A receptor subunit gamma3 |
|
Gene Alias
|
- |
|
Transcripts
|
ENSG00000182256
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Microtubules;Nucleoli; 
|
|
Membrane Info
|
FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q99928
|
|
HGNC ID
|
HGNC:4088
|
|
OMIM ID
|
600233 |
|
Summary
|
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012] |
Target gene [GABRG3] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1004657 |
chr15 |
28 |
28 |
17 |
73 |
View |
| 1016004 |
chr15 |
2 |
0 |
0 |
2 |
View |
| 1017167 |
chr15 |
1 |
0 |
0 |
1 |
View |
Target gene [GABRG3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE68402 - GABRG3 peak across samples
|
Peak Plot
|
> Dataset: GSE100400 - GABRG3 peak across samples
|
Peak Plot
|
> Dataset: GSE131257 - GABRG3 peak across samples
|
Peak Plot
|
|
|
HBV Target gene Detail Information
