Gene Name	HAP1
Gene ID	9001
Gene Full Name	huntingtin associated protein 1
Gene Alias	HAP2|HIP5|HLP|hHLP1
Transcripts	ENSG00000173805
Virus	XMRV
Gene Type	protein-coding
HPA Location Info	Cytosol;Nucleoli;
Membrane Info	Predicted intracellular proteins
Uniport_ID	P54257
HGNC ID	HGNC:4812
OMIM ID	600947
Summary	Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
8000053	chr17	629	321	58	1008	View