Gene Information
|
Gene Name
|
HPRT1 |
|
Gene ID
|
3251
|
|
Gene Full Name
|
hypoxanthine phosphoribosyltransferase 1 |
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Gene Alias
|
HGPRT|HPRT |
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Transcripts
|
ENSG00000165704
|
|
Virus
|
CHIKV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;Mid piece, Principal piece, End piece, Annulus; 
|
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Membrane Info
|
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
P00492
|
|
HGNC ID
|
HGNC:5157
|
|
OMIM ID
|
308000 |
|
Summary
|
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009] |
Target gene [HPRT1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
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CHIKV Target gene Detail Information
