Gene Name	IGFBP5
Gene ID	3488
Gene Full Name	insulin like growth factor binding protein 5
Gene Alias	IBP5
Transcripts	ENSG00000115461
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Vesicles;Secreted to blood;
Membrane Info	Plasma proteins, Predicted secreted proteins
Uniport_ID	P24593
HGNC ID	HGNC:5474
OMIM ID	146734
Summary	Enables insulin-like growth factor I binding activity and receptor ligand activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007486	chr2	19	7	1	27	View
1042627	chr2	8	2	0	10	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
S   GSE199850	scRNA-seq	1	HiSeq X Ten (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
E   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Expression profiling
• scRNA data

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE100400 - IGFBP5 expression across samples

Volcano Plot

Bar Plot