CHIKV Target gene Detail Information

> IRF7 Gene Search Result


Gene Information
Gene Name IRF7
Gene ID 3665
Gene Full Name interferon regulatory factor 7
Gene Alias IMD39|IRF-7|IRF-7H|IRF7A|IRF7B|IRF7C|IRF7H
Transcripts ENSG00000185507
Virus CHIKV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q92985
HGNC ID HGNC:6122
OMIM ID 605047
Summary This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses. [provided by RefSeq, Jul 2021]
Target gene [IRF7] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 24126361 A226V
E1
E1
Chikungunya Fever
G
R
I
L
T
View
2 24905288 P23S
C
Capsid
Chikungunya Fever
R
T
View
3 24905288 V27I
C
Capsid
Chikungunya Fever
R
T
View
4 24905288 A226V
E1
E1
Chikungunya Fever
R
L
T
View
5 24905288 T128K
nsP1
nsP1
Chikungunya Fever
R
T
View
6 24905288 T376M
nsP1
nsP1
Chikungunya Fever
R
T
View