Gene Information
|
Gene Name
|
LCAT |
|
Gene ID
|
3931
|
|
Gene Full Name
|
lecithin-cholesterol acyltransferase |
|
Gene Alias
|
- |
|
Transcripts
|
ENSG00000213398
|
|
Virus
|
XMRV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Secreted to blood;
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins |
|
Uniport_ID
|
P04180
|
|
HGNC ID
|
HGNC:6522
|
|
OMIM ID
|
606967 |
|
Summary
|
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq, Jul 2008] |
Target gene [LCAT] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 8000012 |
chr16 |
53 |
11 |
11 |
75 |
View |
|
|