HBV Target gene Detail Information

> LXN Gene Search Result


Gene Information
Gene Name LXN
Gene ID 56925
Gene Full Name latexin
Gene Alias ECI|TCI
Transcripts ENSG00000079257
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cytosol;
Membrane Info Predicted intracellular proteins
Uniport_ID Q9BS40
HGNC ID HGNC:13347
OMIM ID 609305
Summary This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020]
Target gene [LXN] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000147 chr3 3302 936 1090 5328 View
1000148 chr3 3302 936 1090 5328 View
1000149 chr3 3302 936 1090 5328 View
1000150 chr3 3302 936 1090 5328 View
1000153 chr3 3300 931 1080 5311 View
1000154 chr3 3300 931 1080 5311 View
1000155 chr3 3301 927 1077 5305 View

Target gene [LXN] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - LXN peak across samples

Peak Plot

> Dataset: GSE131257 - LXN peak across samples

Peak Plot