Gene Information
|
Gene Name
|
MARCHF5 |
|
Gene ID
|
54708
|
|
Gene Full Name
|
membrane associated ring-CH-type finger 5 |
|
Gene Alias
|
MARCH-V|MARCH5|MITOL|RNF153 |
|
Transcripts
|
ENSG00000198060
|
|
Virus
|
JEV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Mitochondria;
|
|
Membrane Info
|
Enzymes, Metabolic proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q9NX47
|
|
HGNC ID
|
HGNC:26025
|
|
OMIM ID
|
610637 |
|
Summary
|
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008] |
Target gene [MARCHF5] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
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