Gene Information
|
Gene Name
|
MX2 |
|
Gene ID
|
4600
|
|
Gene Full Name
|
MX dynamin like GTPase 2 |
|
Gene Alias
|
MXB |
|
Transcripts
|
ENSG00000183486
|
|
Virus
|
CHIKV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Plasma proteins, Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
P20592
|
|
HGNC ID
|
HGNC:7533
|
|
OMIM ID
|
147890 |
|
Summary
|
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008] |
Target gene [MX2] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
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CHIKV Target gene Detail Information
