Gene Information
|
Gene Name
|
OAS3 |
|
Gene ID
|
4940
|
|
Gene Full Name
|
2'-5'-oligoadenylate synthetase 3 |
|
Gene Alias
|
p100|p100OAS |
|
Transcripts
|
ENSG00000111331
|
|
Virus
|
CHIKV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Cytosol;Plasma membrane; 
|
|
Membrane Info
|
Enzymes, Predicted intracellular proteins |
|
Uniport_ID
|
Q9Y6K5
|
|
HGNC ID
|
HGNC:8088
|
|
OMIM ID
|
603351 |
|
Summary
|
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq, Jul 2008] |
Target gene [OAS3] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
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|
CHIKV Target gene Detail Information
