Gene Name	OSBPL2
Gene ID	9885
Gene Full Name	oxysterol binding protein like 2
Gene Alias	DFNA67|DNFA67|ORP-2|ORP2
Transcripts	ENSG00000130703
Virus	XMRV
Gene Type	protein-coding
HPA Location Info	Cytosol;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID	Q9H1P3
HGNC ID	HGNC:15761
OMIM ID	606731
Summary	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
8000045	chr20	4169	1852	1415	7436	View