HBV Target gene Detail Information

> PAPPA2 Gene Search Result


Gene Information
Gene Name PAPPA2
Gene ID 60676
Gene Full Name pappalysin 2
Gene Alias PAPP-A2|PAPP-E|PAPPE|PLAC3|SSDA
Transcripts ENSG00000116183
Virus HBV
Gene Type protein-coding
HPA Location Info Endoplasmic reticulum, Vesicles;Secreted in female reproductive system;
Membrane Info Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID Q9BXP8
HGNC ID HGNC:14615
OMIM ID 619485
Summary This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Target gene [PAPPA2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003486 chr1 34 88 9 131 View
1003707 chr1 26 78 16 120 View
1005605 chr1 5 44 2 51 View
1011423 chr1 9 0 0 9 View
1011424 chr1 9 0 0 9 View
1013104 chr1 3 0 2 5 View
1022131 chr1 3 0 2 5 View
1041744 chr1 138 23 48 209 View

Target gene [PAPPA2] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
S
  GSE199850
scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402
Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100400
Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257
ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.


> Dataset: GSE199850 - Gene expression in cell subsets