Gene Information
|
Gene Name
|
PDE1C |
|
Gene ID
|
5137
|
|
Gene Full Name
|
phosphodiesterase 1C |
|
Gene Alias
|
DFNA74|Hcam3|cam-PDE 1C|hCam-3 |
|
Transcripts
|
ENSG00000154678
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Mitochondria, Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q14123
|
|
HGNC ID
|
HGNC:8776
|
|
OMIM ID
|
602987 |
|
Summary
|
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016] |
Target gene [PDE1C] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1009478 |
chr7 |
13 |
0 |
2 |
15 |
View |
| 1009725 |
chr7 |
6 |
3 |
5 |
14 |
View |
| 1012529 |
chr7 |
2 |
4 |
0 |
6 |
View |
| 1014827 |
chr7 |
0 |
3 |
0 |
3 |
View |
| 1014828 |
chr7 |
0 |
3 |
0 |
3 |
View |
| 1018861 |
chr7 |
0 |
0 |
0 |
0 |
View |
| 1022533 |
chr7 |
13 |
0 |
2 |
15 |
View |
| 1022534 |
chr7 |
2 |
4 |
0 |
6 |
View |
| 1022535 |
chr7 |
6 |
3 |
5 |
14 |
View |
| 1043226 |
chr7 |
60 |
1 |
4 |
65 |
View |
| 1043227 |
chr7 |
8 |
5 |
0 |
13 |
View |
Target gene [PDE1C] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE35465
|
Chip-seq;RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE199850
|
scRNA-seq |
1 |
HiSeq X Ten (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE100400 - PDE1C expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
HBV Target gene Detail Information
