Gene Information
|
Gene Name
|
PRMT1 |
|
Gene ID
|
3276
|
|
Gene Full Name
|
protein arginine methyltransferase 1 |
|
Gene Alias
|
ANM1|HCP1|HRMT1L2|IR1B4 |
|
Transcripts
|
ENSG00000126457
|
|
Virus
|
HDV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;
|
|
Membrane Info
|
Enzymes, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q99873
|
|
HGNC ID
|
HGNC:5187
|
|
OMIM ID
|
602950 |
|
Summary
|
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011] |
Target gene [PRMT1] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
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