Gene Information
|
Gene Name
|
PTPRR |
|
Gene ID
|
5801
|
|
Gene Full Name
|
protein tyrosine phosphatase receptor type R |
|
Gene Alias
|
EC-PTP|PCPTP1|PTP-SL|PTPBR7|PTPRQ |
|
Transcripts
|
ENSG00000153233
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Cell Junctions, Cytosol;Secreted - unknown location; 
|
|
Membrane Info
|
Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q15256
|
|
HGNC ID
|
HGNC:9680
|
|
OMIM ID
|
602853 |
|
Summary
|
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011] |
Target gene [PTPRR] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1001721 |
chr12 |
373 |
45 |
97 |
515 |
View |
| 1006966 |
chr12 |
23 |
9 |
0 |
32 |
View |
| 1010282 |
chr12 |
11 |
2 |
0 |
13 |
View |
| 1011185 |
chr12 |
10 |
0 |
0 |
10 |
View |
| 1011416 |
chr12 |
6 |
3 |
0 |
9 |
View |
Target gene [PTPRR] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE35465
|
Chip-seq;RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE35465 - PTPRR peak across samples
|
Peak Plot
|
> Dataset: GSE68402 - PTPRR peak across samples
|
Peak Plot
|
> Dataset: GSE100400 - PTPRR peak across samples
|
Peak Plot
|
> Dataset: GSE131257 - PTPRR peak across samples
|
Peak Plot
|
|
|
HBV Target gene Detail Information
