XMRV Target gene Detail Information

> RBPJ Gene Search Result


Gene Information
Gene Name RBPJ
Gene ID 3516
Gene Full Name recombination signal binding protein for immunoglobulin kappa J region
Gene Alias AOS3|CBF-1|CBF1|IGKJRB|IGKJRB1|KBF2|RBP-J|RBP-J kappa|RBP-JK|RBPJK|RBPSUH|SUH|csl
Transcripts ENSG00000168214
Virus XMRV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q06330
HGNC ID HGNC:5724
OMIM ID 147183
Summary The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
Target gene [RBPJ] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
8000031 chr4 4408 3922 1625 9955 View