XMRV Target gene Detail Information

> RPLP0 Gene Search Result


Gene Information
Gene Name RPLP0
Gene ID 6175
Gene Full Name ribosomal protein lateral stalk subunit P0
Gene Alias L10E|LP0|P0|PRLP0|RPP0|uL10
Transcripts ENSG00000089157
Virus XMRV
Gene Type protein-coding
HPA Location Info Endoplasmic reticulum, Cytosol;
Membrane Info Plasma proteins, Predicted intracellular proteins, Ribosomal proteins
Uniport_ID P05388
HGNC ID HGNC:10371
OMIM ID 180510
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Target gene [RPLP0] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
8000062 chr12 444 315 117 876 View