Gene Name	SIRT4
Gene ID	23409
Gene Full Name	sirtuin 4
Gene Alias	SIR2L4
Transcripts	ENSG00000089163
Virus	XMRV
Gene Type	protein-coding
HPA Location Info
Membrane Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	Q9Y6E7
HGNC ID	HGNC:14932
OMIM ID	604482
Summary	This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
8000062	chr12	444	315	117	876	View