Gene Name	SRGAP2B
Gene ID	647135
Gene Full Name	SLIT-ROBO Rho GTPase activating protein 2B
Gene Alias	SRGAP2L|SRGAP2P2
Transcripts	ENSG00000196369
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Centrosome, Basal body, Cytosol;
Membrane Info	Predicted intracellular proteins
Uniport_ID	P0DMP2
HGNC ID	HGNC:35237
OMIM ID	614703
Summary	This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from incomplete segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2 locus. The encoded protein lacks the GTPase activating protein domain compared to proteins encoded by SLIT-ROBO Rho GTPase activating protein 2. The functionality of the protein encoded by this locus has been questioned, as several normal individuals with homozygous deletions for this locus have been identified, and the expression of this locus appears to be much lower than the similar SLIT-ROBO Rho GTPase activating protein 2C (SRGAP2C) locus. The SRGAP2C locus has been shown to encode a protein that functions antagonistically to SLIT-ROBO Rho GTPase activating protein 2 in cortical neuron development. [provided by RefSeq, Dec 2012]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6012362	chr1	12	5	6	23	View
6024952	chr1	0	0	3	3	View
6033325	chr1	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - SRGAP2B peak across samples

Peak Plot