Gene Name	TFEC
Gene ID	22797
Gene Full Name	transcription factor EC
Gene Alias	TCFEC|TFE-C|TFEC-L|TFECL|bHLHe34|hTFEC-L
Transcripts	ENSG00000105967
Virus	XMRV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Cytosol;
Membrane Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	O14948
HGNC ID	HGNC:11754
OMIM ID	604732
Summary	This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
8000039	chr7	2936	1596	1150	5682	View