Gene Name	TKTL1
Gene ID	8277
Gene Full Name	transketolase like 1
Gene Alias	TKR|TKT2
Transcripts	ENSG00000007350
Virus	XMRV
Gene Type	protein-coding
HPA Location Info	Cytosol;
Membrane Info	Enzymes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID	P51854
HGNC ID	HGNC:11835
OMIM ID	300044
Summary	The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
8000046	chrX	4991	3932	2008	10931	View