Gene Information
|
Gene Name
|
TNFRSF9 |
|
Gene ID
|
3604
|
|
Gene Full Name
|
TNF receptor superfamily member 9 |
|
Gene Alias
|
4-1BB|CD137|CDw137|ILA|IMD109 |
|
Transcripts
|
ENSG00000049249
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Nucleoli; 
|
|
Membrane Info
|
Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
Q07011
|
|
HGNC ID
|
HGNC:11924
|
|
OMIM ID
|
602250 |
|
Summary
|
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008] |
Target gene [TNFRSF9] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1001732 |
chr1 |
420 |
87 |
4 |
511 |
View |
| 1022212 |
chr1 |
420 |
87 |
4 |
511 |
View |
Target gene [TNFRSF9] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE68402 - TNFRSF9 peak across samples
|
Peak Plot
|
> Dataset: GSE100400 - TNFRSF9 peak across samples
|
Peak Plot
|
|
|
HBV Target gene Detail Information
