Gene Information
|
Gene Name
|
XPO1 |
|
Gene ID
|
7514
|
|
Gene Full Name
|
exportin 1 |
|
Gene Alias
|
CRM-1|CRM1|emb|exp1 |
|
Transcripts
|
ENSG00000082898
|
|
Virus
|
HDV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nuclear membrane;Vesicles, Cytosol; 
|
|
Membrane Info
|
Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
O14980
|
|
HGNC ID
|
HGNC:12825
|
|
OMIM ID
|
602559 |
|
Summary
|
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015] |
Target gene [XPO1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
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HDV Target gene Detail Information
