HTLV1 Target gene Detail Information

> ACVR1C Gene Search Result


Gene Information
Gene Name ACVR1C
Gene ID 130399
Gene Full Name activin A receptor type 1C
Gene Alias ACVRLK7|ALK7
Transcripts ENSG00000123612
Virus HTLV1
Gene Type protein-coding
HPA Location Info Intracellular and membrane;
Membrane Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8NER5
HGNC ID HGNC:18123
OMIM ID 608981
Summary ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
Target gene [ACVR1C] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6006857 chr2 54 6 2 62 View

Target gene [ACVR1C] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ACVR1C peak across samples

Peak Plot