HBV Target gene Detail Information

> ALDH18A1 Gene Search Result


Gene Information
Gene Name ALDH18A1
Gene ID 5832
Gene Full Name aldehyde dehydrogenase 18 family member A1
Gene Alias ADCL3|ARCL3A|GSAS|P5CS|PYCS|SPG9|SPG9A|SPG9B
Transcripts ENSG00000059573
Virus HBV
Gene Type protein-coding
HPA Location Info Mitochondria;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P54886
HGNC ID HGNC:9722
OMIM ID 138250
Summary This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]
Target gene [ALDH18A1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1038997 chr10 219 37 40 296 View
1038998 chr10 218 37 38 293 View
1038999 chr10 218 36 37 291 View
1039000 chr10 218 36 37 291 View
1039001 chr10 218 36 37 291 View
1039002 chr10 217 36 37 290 View
1039003 chr10 217 35 37 289 View
1039004 chr10 217 34 37 288 View
1039005 chr10 217 33 37 287 View
1039006 chr10 217 33 36 286 View
1039007 chr10 217 33 35 285 View
1039008 chr10 217 32 32 281 View
1039009 chr10 217 32 31 280 View
1039010 chr10 217 32 31 280 View
1039011 chr10 217 32 31 280 View
1039012 chr10 217 31 30 278 View
1039013 chr10 216 29 28 273 View
1039014 chr10 216 29 27 272 View
1039015 chr10 216 29 26 271 View
1039016 chr10 216 29 26 271 View
1039017 chr10 216 29 25 270 View
1039018 chr10 216 27 25 268 View
1039019 chr10 216 27 20 263 View
1039020 chr10 216 27 20 263 View
1039021 chr10 216 27 20 263 View
1039022 chr10 215 26 18 259 View
1039023 chr10 215 26 16 257 View
1039024 chr10 214 25 16 255 View

Target gene [ALDH18A1] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - ALDH18A1 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE94660 - ALDH18A1 expression across samples

Volcano Plot

Bar Plot