Gene Name	ANXA2
Gene ID	302
Gene Full Name	annexin A2
Gene Alias	ANX2|ANX2L4|CAL1H|HEL-S-270|LIP2|LPC2|LPC2D|P36|PAP-IV
Transcripts	ENSG00000182718
Virus	HEV
Gene Type	protein-coding
HPA Location Info	Plasma membrane;Cytosol;Secreted to blood;
Membrane Info	Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters
Uniport_ID	P07355
HGNC ID	HGNC:537
OMIM ID	151740
Summary	This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	39793027	C18A	ORF3	ORF3	Cell line	G T	View
2	39793027	C18S	ORF3	ORF3	Cell line	G T	View
3	39793027	C21A	ORF3	ORF3	Cell line	G T	View
4	39793027	C21S	ORF3	ORF3	Cell line	G T	View

Data ID	Experiment type	Sample number	Platform
GSE262469	RNA-seq	15	Illumina NovaSeq 6000 (Homo sapiens)
GSE251924	RNA-seq	6	Illumina NovaSeq 6000 (Homo sapiens)
GSE274780	RNA-seq	12	Illumina NextSeq 500 (Homo sapiens)