HBV Target gene Detail Information

> ARHGAP42 Gene Search Result


Gene Information
Gene Name ARHGAP42
Gene ID 143872
Gene Full Name Rho GTPase activating protein 42
Gene Alias AD031|GRAF3|TMEM133
Transcripts ENSG00000165895
Virus HBV
Gene Type protein-coding
HPA Location Info Nuclear speckles;Cytosol;
Membrane Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID A6NI28
HGNC ID HGNC:26545
OMIM ID 615936
Summary This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
Target gene [ARHGAP42] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005912 chr11 18 6 22 46 View
1009729 chr11 0 12 2 14 View
1012699 chr11 6 0 0 6 View
1016266 chr11 1 0 0 1 View
1023286 chr11 1 0 0 1 View
1023659 chr11 0 12 2 14 View
1041924 chr11 1 3 0 4 View
1041925 chr11 3 13 2 18 View

Target gene [ARHGAP42] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - ARHGAP42 expression across samples

Volcano Plot

Bar Plot