HTLV1 Target gene Detail Information

> ASXL3 Gene Search Result


Gene Information
Gene Name ASXL3
Gene ID 80816
Gene Full Name ASXL transcriptional regulator 3
Gene Alias BRPS|KIAA1713
Transcripts ENSG00000141431
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q9C0F0
HGNC ID HGNC:29357
OMIM ID 615115
Summary This gene encodes a protein containing a plant homeodomain (PHD) zinc finger domain that plays a role in the regulation of gene transcription. The encoded protein has been shown to negatively regulate lipogenesis by binding to and inhibiting the transcriptional activity of two nuclear hormone receptors, oxysterols receptor LXR-alpha (LXRalpha) and thyroid hormone receptor beta (TRbeta). The encoded protein may also inhibit histone deubiquitination. Mutations in this gene have been identified in human patients with Bainbridge-Ropers syndrome, which is characterized by feeding difficulties, developmental delay and other features. [provided by RefSeq, May 2017]
Target gene [ASXL3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001785 chr18 286 35 27 348 View
6007866 chr18 51 0 0 51 View

Target gene [ASXL3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ASXL3 peak across samples

Peak Plot